LOCUS BC030195 911 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens granzyme B (granzyme 2, cytotoxic
T-lymphocyte-associated serine esterase 1), mRNA (cDNA clone
MGC:34374 IMAGE:5223876), complete cds.
ACCESSION BC030195
VERSION BC030195.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 911)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 911)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: m Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 32483414.
FEATURES Location/Qualifiers
source 1..911
/db_xref="H-InvDB:HIT000040974"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34374 IMAGE:5223876"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..911
/gene="GZMB"
/gene_synonym="CCPI"
/gene_synonym="CGL-1"
/gene_synonym="CGL1"
/gene_synonym="CSP-B"
/gene_synonym="CTSGL1"
/gene_synonym="HLP"
/gene_synonym="SECT"
/db_xref="GeneID:3002"
/db_xref="HGNC:HGNC:4709"
/db_xref="MIM:123910"
CDS 23..766
/gene="GZMB"
/gene_synonym="CCPI"
/gene_synonym="CGL-1"
/gene_synonym="CGL1"
/gene_synonym="CSP-B"
/gene_synonym="CTSGL1"
/gene_synonym="HLP"
/gene_synonym="SECT"
/codon_start=1
/product="granzyme B (granzyme 2, cytotoxic
T-lymphocyte-associated serine esterase 1)"
/protein_id="AAH30195.1"
/db_xref="GeneID:3002"
/db_xref="HGNC:HGNC:4709"
/db_xref="MIM:123910"
/translation="MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQK
SLKRCGGFLIQDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNP
KNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTL
QEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVS
YGRNNGMPPRACTKVSSFVHWIKKTMKRH"
BASE COUNT 272 a 242 c 228 g 169 t
ORIGIN
1 ccagggcagc cttcctgaga agatgcaacc aatcctgctt ctgctggcct tcctcctgct
61 gcccagggca gatgcagggg agatcatcgg gggacatgag gccaagcccc actcccgccc
121 ctacatggct tatcttatga tctgggatca gaagtctctg aagaggtgcg gtggcttcct
181 gatacaagac gacttcgtgc tgacagctgc tcactgttgg ggaagctcca taaatgtcac
241 cttgggggcc cacaatatca aagaacagga gccgacccag cagtttatcc ctgtgaaaag
301 acccatcccc catccagcct ataatcctaa gaacttctcc aacgacatca tgctactgca
361 gctggagaga aaggccaagc ggaccagagc tgtgcagccc ctcaggctac ctagcaacaa
421 ggcccaggtg aagccagggc agacatgcag tgtggccggc tgggggcaga cggcccccct
481 gggaaaacac tcacacacac tacaagaggt gaagatgaca gtgcaggaag atcgaaagtg
541 cgaatctgac ttacgccatt attacgacag taccattgag ttgtgcgtgg gggacccaga
601 gattaaaaag acttccttta agggggactc tggaggccct cttgtgtgta acaaggtggc
661 ccagggcatt gtctcctatg gacgaaacaa tggcatgcct ccacgagcct gcaccaaagt
721 ctcaagcttt gtacactgga taaagaaaac catgaaacgc cactaactac aggaagcaaa
781 ctaagccccc gctgtgatga aacaccttct ctggagccaa gtccagattt acactgggag
841 aggtgccagc aactgaataa atacctctta gctgagtgga aaaaaaaaaa aaaaaaaaaa
901 aaaaaaaaaa a
//