LOCUS BC030010 3887 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens epidermal growth factor receptor pathway substrate 8,
mRNA (cDNA clone MGC:26317 IMAGE:4820933), complete cds.
ACCESSION BC030010
VERSION BC030010.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3887)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3887)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC030010.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 33 Row: a Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56682952.
FEATURES Location/Qualifiers
source 1..3887
/db_xref="H-InvDB:HIT000040928"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26317 IMAGE:4820933"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3887
/gene="EPS8"
/db_xref="GeneID:2059"
/db_xref="HGNC:HGNC:3420"
/db_xref="MIM:600206"
CDS 250..2718
/gene="EPS8"
/codon_start=1
/product="epidermal growth factor receptor pathway
substrate 8"
/protein_id="AAH30010.1"
/db_xref="GeneID:2059"
/db_xref="HGNC:HGNC:3420"
/db_xref="MIM:600206"
/translation="MNGHISNHPSSFGMYPSQMNGYGSSPTFSQTDREHGSKTSAKAL
YEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWT
QDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMHSCSYDSVLALVCKEPTQNK
PDLHLFQCDEVKANLISEDIESAISDSKGGKQKRRPDALRMISNADPSIPPPPRAPAP
APPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYHEQEETPEMMAARIDRDVQILNHI
LDDIEFFITKLQKAAEAFSELSKRKKNKKGKRKGPGEGVLTLRAKPPPPDEFLDCFQK
FKHGFNLLAKLKSHIQNPSAADLVHFLFTPLNMVVQATGGPELASSVLSPLLNKDTID
FLNYTVNGDERQLWMSLGGTWMKARAEWPKEQFIPPYVPRFRNGWEPPMLNFMGATME
QDLYQLAESVANVAEHQRKQEIKRLSTEHSSVSEYHPADGYAFSSNIYTRGSHLDQGE
AAVAFKPTSNRHIDRNYEPLKTQPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQ
WWKVRNASGDSGFVPNNILDIVRPPESGLGRADPPYTHTIQKQRMEYGPRPADTPPAP
SPPPTPVPVPVPLPPSTPAPVPVSKVPANITRQNSSSSDSGGSIVRDSQRHKQLPVDR
RKSQMEEVQDELIHRLTIGRSAAQKKFHVPRQNVPVINITYDSTPEDVKTWLQSKGFN
PVTVNSLGVLNGAQLFSLNKDELRTVCPEGARVYSQITVQKAALEDSSGSSELQEIMR
RRQEKISAAASDSGVESFDEGSSH"
BASE COUNT 1194 a 793 c 854 g 1046 t
ORIGIN
1 agacttcaca ggcagcagct agcgaggcgg tctcgcccgg cgcgaggccg gcgctgtgct
61 cgcctcggag atcgctgctc tttagctggg tgcagaaggc ggctccgcgg ctcgcggacg
121 actggctggg cgcgaatcag attggggggc tttctcccgg tcccctccca cctcgtctgg
181 gctcgcggcg tctccgggga aagccgtggc cccgagggcg gatccgagaa cacacaagtg
241 aaagacacaa tgaatggtca tatttctaat catcccagta gttttggaat gtacccatct
301 cagatgaatg gctacggatc atcacctacc ttttcccaga cggacagaga acatggttca
361 aaaacaagtg caaaggccct ttatgaacaa aggaagaatt atgcacggga cagtgtcagc
421 agtgtgtcag atatatctca ataccgtgtt gaacacttga ctacctttgt cctggatcgg
481 aaagatgcta tgatcactgt tgatgatgga ataaggaaat tgaaattgct tgatgccaag
541 ggcaaagtgt ggactcaaga tatgattctt caagtggatg acagagctgt gagcctgatt
601 gatttagaat caaagaatga actggagaat tttcctttaa acacaatcca gcactgccaa
661 gctgtgatgc attcatgcag ctatgattca gttcttgcac tggtgtgcaa agagccaacc
721 cagaacaagc cagatcttca tctcttccag tgtgatgagg ttaaggcaaa cctaattagt
781 gaagatattg aaagtgcaat cagtgacagt aaaggaggga aacagaagag gcggcccgac
841 gccctgagga tgatttccaa tgcagaccct agtataccgc ctccacccag agctcctgcc
901 cctgcgcccc ctgggaccgt cacccaggtg gatgttagaa gtcgagtggc agcctggtct
961 gcatgggcag ccgaccaagg ggactttgag aaaccaaggc agtatcatga gcaggaagaa
1021 acacctgaga tgatggcagc ccgcattgac agagatgtgc aaatcttaaa ccacattttg
1081 gatgacattg aattttttat cacaaaactc caaaaagcag cagaagcatt ttctgagctt
1141 tctaaaagga agaaaaacaa gaaaggtaaa aggaaaggac caggagaggg tgttttaacg
1201 ctgcgggcaa aacctccacc tcctgatgaa tttcttgact gtttccaaaa gtttaaacac
1261 ggatttaacc ttctggccaa actgaagtct catattcaga atcctagtgc tgcagatttg
1321 gttcactttt tgtttactcc attaaatatg gtggtgcagg caacaggagg tcctgaacta
1381 gccagttcag tacttagtcc cctattgaat aaggacacaa ttgatttctt aaattatact
1441 gtcaatggtg atgaacggca gctgtggatg tcattgggag gaacttggat gaaagccaga
1501 gcagagtggc caaaagaaca gtttattcca ccatatgttc cacgattccg caatggctgg
1561 gagcccccaa tgctgaactt tatgggagcc acaatggaac aagatcttta tcaactggca
1621 gaatctgtgg caaatgtagc agaacatcag cgcaaacagg aaataaaaag attatccaca
1681 gagcattcca gtgtatcaga gtatcatcca gccgatggct atgcgttcag tagcaacatt
1741 tacacaagag gatcccacct ggaccaaggg gaagctgctg ttgcttttaa gccaacttct
1801 aatcgccata tagatagaaa ttatgaacca ctcaaaacac aacccaagaa atatgccaaa
1861 tccaagtatg actttgtagc aaggaacaac agtgagctct cggttctaaa ggatgatatt
1921 ttagagatac ttgatgatcg gaagcaatgg tggaaagttc gaaatgcaag tggagactct
1981 ggatttgtgc caaataacat tttggatatt gtgagacctc cagaatctgg attggggcgt
2041 gctgatccac cttatactca tactatacag aaacaaagga tggagtatgg cccaagacca
2101 gctgatactc cccctgctcc atcacctcct ccaacaccag ttcctgttcc tgttcccctt
2161 cccccttcca ctccagcacc tgttcctgtg tcaaaggtcc cagcaaatat aacacgtcaa
2221 aacagcagct ccagtgacag tggtggcagt atcgtgcgag acagccagag acacaaacaa
2281 cttccggtgg accgaaggaa atctcagatg gaggaagtgc aagatgaact catccacaga
2341 ctgaccattg gtcggagtgc cgctcagaag aaattccatg tgccacggca gaacgtgcca
2401 gttatcaata tcacttacga ctccacacca gaggatgtga agacgtggtt acagtcaaag
2461 ggattcaacc ctgtgactgt caatagtctt ggagtattaa atggtgcaca acttttctct
2521 ctcaataagg atgaactgag gacagtctgc cctgaagggg cgagagtcta tagccaaatc
2581 actgtacaaa aagctgcatt ggaggatagc agtggcagct ccgagttaca agaaattatg
2641 agaagacgac aggaaaaaat cagtgctgcc gctagtgatt caggagtgga atcttttgat
2701 gaaggaagca gtcactaatt tgtttgtttg tatttaaact ccattgtttt tggcattatt
2761 ccaacatgct ttgttttaag aagccttgaa gggaatgtca gattcatttt tcttgatgta
2821 atttatcacc ataaaaaaaa aacccatgca aacctgagtg agcacaggat ttgcttctag
2881 gcccattatt tttattaaaa ctgaaaaaat ttaaactgaa ttttttgacc ttggaaaata
2941 tttttcttac tttaccaagg tgaagtttcc ttaattagac taattatttt atccccatcc
3001 cagggtataa acaggaattg ttttgatagt ggtggagtta ttcactgcaa caaagcaaca
3061 atgttgtcca tgattcaaaa tctaagcagt ttcgattttg cctgtgaata tggtgtctgt
3121 cattcagggc atagctcact gtaggctagc ctctgcttac ttaagtctct tctctgacat
3181 actcaatgga agaatattta gatttattta aagttcttaa tgccaacagt ttaaaaaaaa
3241 attaaaacat ttgaatgaac tgtaaagtac agccatacct tggacatgca aatataaatc
3301 tatggagcat tctcaagaca gtttgtcatg gctctgttga ttgcaactcc ttgtatagct
3361 tgtattttga tttagtttat attctgctta ttatgtatac tgtgttctta tatatgagaa
3421 agcacaaatg cgaaagaggt catgtcttct caaaatctag caaaggaagt agtctgcatt
3481 ggtgtgcatt acagtatttt gcttaatgaa agcctcagtt ctgaatgttg atatgagtag
3541 ttaaaaggaa gtggggccat tttatgtgtt tatctgtgtc aagtatttct ggtaataaga
3601 agcacttaat ttacacatat tttaatcctg tgaaagattc cacatagaga aaagaaagat
3661 acctaacctt caacaaatgt tatttttgga aacacaattt ttgtcattaa atgttatatt
3721 atttcacata tataaaacag atgttatgta agaatgttgt atattttaac ataaatcatt
3781 tagagaaatt atctagattc attaattttc atagtgcctt tttcacatga gtcagctgga
3841 aagtctgcaa taaacagtat ttgctgtctg ttaaaaaaaa aaaaaaa
//