LOCUS BC029795 1598 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens brain-derived neurotrophic factor, mRNA (cDNA clone
MGC:34632 IMAGE:5193877), complete cds.
ACCESSION BC029795
VERSION BC029795.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1598)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1598)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 50 Row: l Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34106708.
FEATURES Location/Qualifiers
source 1..1598
/db_xref="H-InvDB:HIT000040877"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34632 IMAGE:5193877"
/tissue_type="Brain, adult, 6 pooled whole brains"
/clone_lib="NIH_MGC_114"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1598
/gene="BDNF"
/gene_synonym="MGC34632"
/db_xref="GeneID:627"
/db_xref="HGNC:HGNC:1033"
/db_xref="MIM:113505"
CDS 332..1075
/gene="BDNF"
/gene_synonym="MGC34632"
/codon_start=1
/product="brain-derived neurotrophic factor"
/protein_id="AAH29795.1"
/db_xref="GeneID:627"
/db_xref="HGNC:HGNC:1033"
/db_xref="MIM:113505"
/translation="MTILFLTMVISYFGCMKAAPMKEANIRGQGGLAYPGVRTHGTLE
SVNGPKAGSRGLTSLADTFEHMIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPL
EPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMS
GGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRAL
TMDSKKRIGWRFIRIDTSCVCTLTIKRGR"
BASE COUNT 505 a 327 c 365 g 401 t
ORIGIN
1 ggctgctctc gctgccgctc cccccggcga actagcatga aatctccctg cctctgccga
61 gatcaaatgg agcttctcgc tgatggggtg cgagtattac ctccgccatg caatttccac
121 tatcaataat ttaacttctt tgctgcagaa cagaaggagt acataccggg caccaaagac
181 tcgcgccccc tccccccttt aattaagcga agggaacgtg aaaaaataat agagtgtggg
241 agttttgggg ccgaagtctt tcccggagca gctgccttga tggttacttt gacaagtagt
301 gactgaaaag ttccaccagg tgagaagagt gatgaccatc cttttcctta ctatggttat
361 ttcatacttt ggttgcatga aggctgcccc catgaaagaa gcaaacatcc gaggacaagg
421 tggcttggcc tacccaggtg tgcggaccca tgggactctg gagagcgtga atgggcccaa
481 ggcaggttca agaggcttga catcattggc tgacactttc gaacacatga tagaagagct
541 gttggatgag gaccagaaag ttcggcccaa tgaagaaaac aataaggacg cagacttgta
601 cacgtccagg gtgatgctca gtagtcaagt gcctttggag cctcctcttc tctttctgct
661 ggaggaatac aaaaattacc tagacgctgc aaacatgtcc atgagggtcc ggcgccactc
721 tgaccctgcc cgccgagggg agctgagcgt gtgtgacagt attagtgagt gggtaacggc
781 ggcagacaaa aagactgcag tggacatgtc gggcgggacg gtcacagtcc ttgaaaaggt
841 ccctgtatca aaaggccaac tgaagcaata cttctacgag accaagtgca atcccatggg
901 ttacacaaaa gaaggctgca ggggcataga caaaaggcat tggaactccc agtgccgaac
961 tacccagtcg tacgtgcggg cccttaccat ggatagcaaa aagagaattg gctggcgatt
1021 cataaggata gacacttctt gtgtatgtac attgaccatt aaaaggggaa gatagtggat
1081 ttatgttgta tagattagat tatattgaga caaaaattat ctatttgtat atatacataa
1141 cagggtaaat tattcagtta agaaaaaaat aattttatga actgcatgtg taaatgaagt
1201 ttatacagta cagtggttct acaatctatt tattggacat gtccatgacc agaagggaaa
1261 cagtcatttg cgcacaactt aaaaagtctg cattacattc cttgataatg ttgtggtttg
1321 ttgccgttgc caagaactga aaacataaaa agttaaaaaa aataataaat tgcatgctgc
1381 tttaattgtg aattgataat aaactgtcct ctttcagaaa acagaaaaaa acacacacac
1441 acacaacaaa aatttgaacc aaaacattcc gtttacattt tagacagtaa gtatcttcgt
1501 tcttgttagt actatatctg ttttactgct tttaacttct gatagcgttg gaattaaaac
1561 aatgtcaagg tgaaaaaaaa aaaaaaaaaa aaaaaaaa
//