LOCUS BC028983 2668 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens fragile X mental retardation, autosomal homolog 1,
mRNA (cDNA clone MGC:29858 IMAGE:5122574), complete cds.
ACCESSION BC028983
VERSION BC028983.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2668)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2668)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 42 Row: n Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 61835147.
FEATURES Location/Qualifiers
source 1..2668
/db_xref="H-InvDB:HIT000040657"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29858 IMAGE:5122574"
/tissue_type="Cervix, carcinoma"
/clone_lib="NIH_MGC_12"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2668
/gene="FXR1"
/db_xref="GeneID:8087"
/db_xref="HGNC:HGNC:4023"
/db_xref="MIM:600819"
CDS 11..1630
/gene="FXR1"
/codon_start=1
/product="fragile X mental retardation, autosomal homolog
1"
/protein_id="AAH28983.1"
/db_xref="GeneID:8087"
/db_xref="HGNC:HGNC:4023"
/db_xref="MIM:600819"
/translation="MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPF
NEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDAT
YNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIF
YHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAA
FHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKAR
GFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVP
FVFVGTKESIGNVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRG
PNYTSGYGTNSELSNPSETESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGRGRSVS
GGRGRGGPRGGKSSISSVLKDPDSNPYSLLDNTESDQTADTDASESHHSTNRRRRSRR
RRTDEDAVLMDGMTESDTASVNENGLGKRCD"
BASE COUNT 864 a 435 c 615 g 754 t
ORIGIN
1 cggttccaac atggcggagc tgacggtgga ggttcgcggc tctaacgggg ctttctacaa
61 gggatttatc aaagatgttc atgaagactc ccttacagtt gtttttgaaa ataattggca
121 accagaacgc caggttccat ttaatgaagt tagattacca ccaccacctg atataaaaaa
181 agaaattagt gaaggagatg aagtagaggt atattcaaga gcaaatgacc aagagccatg
241 tgggtggtgg ttggctaaag ttcggatgat gaaaggagaa ttttatgtca ttgaatatgc
301 tgcttgtgac gctacttaca atgaaatagt cacatttgaa cgacttcggc ctgtcaatca
361 aaataaaact gtcaaaaaaa ataccttctt taaatgcaca gtggatgttc ctgaggattt
421 gagagaggcg tgtgctaatg aaaatgcaca taaagatttt aagaaagcag taggagcatg
481 cagaattttt taccatccag aaacaacaca gctaatgata ctgtctgcca gtgaagcaac
541 tgtgaagaga gtaaacatct taagtgacat gcatttgcga agtattcgta cgaagttgat
601 gcttatgtcc agaaatgaag aggccactaa gcatttagaa tgcacaaaac aacttgcagc
661 agcttttcat gaggaatttg ttgtgagaga agatttaatg ggcctggcaa taggaacaca
721 tggtagtaac atccagcaag ctaggaaggt tcctggagtt accgccattg agctagatga
781 agatactgga acattcagaa tctacggaga gagtgctgat gctgtaaaaa aggctagagg
841 tttcttggaa tttgtggagg attttattca ggttcctagg aatctcgttg gaaaagtaat
901 tggaaaaaat ggcaaagtta ttcaagaaat agtggacaaa tctggtgtgg ttcgagtgag
961 aattgaaggg gacaatgaaa ataaattacc cagagaagac ggtatggttc catttgtatt
1021 tgttggcact aaagaaagca ttggaaatgt gcaggttctt ctagagtatc atattgccta
1081 tctaaaggaa gtagaacagc taagaatgga acgcctacag attgatgaac agctgcgaca
1141 gattggttct aggtcttata gcggaagagg cagaggtcgt cggggaccta attacacctc
1201 cggttatggt acaaattctg agctgtctaa cccctctgaa acggaatctg agcgtaaaga
1261 cgagctgagt gattggtcat tggcaggaga agatgatcga gacagccgac atcagcgtga
1321 cagcaggaga cgcccaggag gaagaggcag aagtgtttca gggggtcgag gtcgtggtgg
1381 accacgtggt ggcaaatcct ccatcagttc tgtgctcaaa gatccagaca gcaatccata
1441 cagcttactt gataatacag aatcagatca gactgcagac actgatgcca gcgaatctca
1501 tcacagtact aaccgtcgta ggcggtctcg tagacgaagg actgatgaag atgctgttct
1561 gatggatgga atgactgaat ctgatacagc ttcagttaat gaaaatgggc taggcaaaag
1621 atgtgattga agagcatggt ccttcagaaa aggcaataaa cggcccaact agtgcttctg
1681 gcgatgacat ttctaagcta cagcgtactc caggagaaga aaagattaat accttaaaag
1741 aagaaaacac tcaagaagca gcagtcctga atggtgtttc ataaactgaa gaagttccta
1801 gtttacagtt cttttacatt acatttacaa tagtgcttgt acaagcttgc caaagataga
1861 atatggatcg ccagtcttta catcgcactt tcagttcctc catttggaat tcaaaaaggg
1921 gagggatcct gaagaaatca tatgttaaac atactttgac acctactgtg ttataaaata
1981 tatcatcaga tgtgccttga gaatagtata tgtaacatta aaaaaaagtt gctggctata
2041 ggaaatgtta ttttgttttc aaaatatggc agagatgggg ggtggtgggt ggggtgggat
2101 ccctaacgta atattcttta tgaaagcatt agctgctttt gttacatttt taatatgcaa
2161 ccacttcttc acctgaggaa aactagaatg aaatgcagtc taaaatattt tgcactgaat
2221 tgtaatttct tcattagttt agtctggaaa ctggtctgtt ttaatgtgtt ttttaaatgc
2281 tgtatgtaga ggaaaatctg cagaccactg gaatacattt gttaaactct catctgcagg
2341 gacactgggc gatacttggc agtgactgtt ctaccttgag gctttgtttg gtttatttat
2401 taaagtgtac agtatttaaa aatcaaacat agctttagtt aaaacactaa gctgaattag
2461 tcatgtccat tcagacataa cctgaactac tgaaaagatc aatttccaga aggtttattc
2521 tgtataaact acatgttagt cttcagtaga gtatcttttt tttttccttt tttttttttt
2581 tatttcggtt gtttgatgtg caatatgttt ttgtatgcag gtagtaaata aactttgatc
2641 ttccattaaa aaaaaaaaaa aaaaaaaa
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