LOCUS BC028940 3407 bp mRNA linear HUM 29-AUG-2008
DEFINITION Homo sapiens sterol O-acyltransferase 1, mRNA (cDNA clone MGC:29940
IMAGE:4991365), complete cds.
ACCESSION BC028940
VERSION BC028940.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3407)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3407)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 42 Row: i Column: 23.
FEATURES Location/Qualifiers
source 1..3407
/db_xref="H-InvDB:HIT000040651"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29940 IMAGE:4991365"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_10"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3407
/gene="SOAT1"
/gene_synonym="ACACT"
/gene_synonym="ACAT"
/gene_synonym="ACAT1"
/gene_synonym="RP11-215I23.2"
/db_xref="GeneID:6646"
/db_xref="HGNC:HGNC:11177"
/db_xref="MIM:102642"
CDS 64..1716
/gene="SOAT1"
/gene_synonym="ACACT"
/gene_synonym="ACAT"
/gene_synonym="ACAT1"
/gene_synonym="RP11-215I23.2"
/codon_start=1
/product="sterol O-acyltransferase 1"
/protein_id="AAH28940.1"
/db_xref="GeneID:6646"
/db_xref="HGNC:HGNC:11177"
/db_xref="MIM:102642"
/translation="MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDI
KQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEG
EKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVD
YIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLI
RSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVP
RVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCF
FYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAF
AEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAML
AVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLF
LGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF"
BASE COUNT 940 a 628 c 681 g 1158 t
ORIGIN
1 gcttcccggc tctgccctct tggccgaagt gcccgctgcc gggcgcgggc ctcagacaat
61 acaatggtgg gtgaagagaa gatgtctcta agaaaccggc tgtcaaagtc cagggaaaat
121 cctgaggaag atgaagacca gagaaaccct gcaaaggagt ccctagagac acctagtaat
181 ggtcgaattg acataaaaca gttgatagca aagaagataa agttgacagc agaggcagag
241 gaattgaagc cattttttat gaaggaagtt ggcagtcact ttgatgattt tgtgaccaat
301 ctcattgaaa agtcagcatc attagataat ggtgggtgcg ctctcacaac cttttctgtt
361 cttgaaggag agaaaaacaa ccatagagcg aaggatttga gagcacctcc agaacaagga
421 aagattttta ttgcaaggcg ctctctctta gatgaactgc ttgaagtgga ccacatcaga
481 acaatatatc acatgtttat tgccctcctc attctcttta tcctcagcac acttgtagta
541 gattacattg atgaaggaag gctggtgctt gagttcagcc tcctgtctta tgcttttggc
601 aaatttccta ccgttgtttg gacctggtgg atcatgttcc tgtctacatt ttcagttccc
661 tattttctgt ttcaacattg ggccactggc tatagcaaga gttctcatcc gctgatccgt
721 tctctcttcc atggctttct tttcatgatc ttccagattg gagttctagg ttttggacca
781 acatatgttg tgttagcata tacactgcca ccagcttccc ggttcatcat tatattcgag
841 cagattcgtt ttgtaatgaa ggcccactca tttgtcagag agaacgtgcc tcgggtacta
901 aattcagcta aggagaaatc aagcactgtt ccaataccta cagtcaacca gtatttgtac
961 ttcttatttg ctcctaccct tatctaccgt gacagctatc ccaggaatcc cactgtaaga
1021 tggggttatg tcgctatgaa gtttgcacag gtctttggtt gctttttcta tgtgtactac
1081 atctttgaaa ggctttgtgc ccccttgttt cggaatatca aacaggagcc cttcagcgct
1141 cgtgttctgg tcctatgtgt atttaactcc atcttgccag gtgtgctgat tctcttcctt
1201 actttttttg cctttttgca ctgctggctc aatgcctttg ctgagatgtt acgctttggt
1261 gacaggatgt tctataagga ttggtggaac tccacgtcat actccaacta ttatagaacc
1321 tggaatgtgg tggtccatga ctggctatat tactatgctt acaaggactt tctctggttt
1381 ttctccaaga gattcaaatc tgctgccatg ttagctgtct ttgctgtatc tgctgtagta
1441 cacgaatatg ccttggctgt ttgcttgagc tttttctatc ccgtgctctt cgtgctcttc
1501 atgttctttg gaatggcttt caacttcatt gtcaatgata gtcggaaaaa gccgatttgg
1561 aatgttctga tgtggacttc tcttttcttg ggcaatggag tcttactctg cttttattct
1621 caagaatggt atgcacgtca gcactgtcct ctgaaaaatc ccacattttt ggattatgtc
1681 cggccacgtt cctggacttg tcgttacgtg ttttagaagc ttggactttg tttcctcctt
1741 gtcactgaag attgggtagc tccctgattt ggagccagct gtttccagtt gttactgaag
1801 ttatctgtgt tatttggacc actccaggct ttacagatga ctcactccat tcctaggtca
1861 cttgaagcca aactgttgga agttcactgg agtcttgtac acttaagcag agcagaagtt
1921 tttttgtggg gctgggtggg gggagaagac cgactaacag ctgaagtaat gacagattgt
1981 tgctgggtca tatcagcttt atcccttggt aattatatct gttttgtttc ttgactctgt
2041 ccaatcagag aataaacatc atagtttctt ggccactgaa ttagccaaaa cacttaggaa
2101 gaaatcactt aaatacctct ggcttagaaa ttttttcatg cacactgttg gaatgtatgc
2161 taattgaaca tgcaattggg gaagaaaaaa tgtagaatga tttttgctat ttctagtaga
2221 aagaaaatgt ctgttttcca aagataatgt tatacatcct attttgtaat ttttttgaaa
2281 aaagttcaat gttcagtttt ccttagtttt taccttgttt tctctatagg tcatgatttc
2341 tgtgaagcaa aaagatgcct tttaccatga attcttgagt ttacatcaat aatattgtat
2401 attaagggga tcagaagtag gaaggaaaaa ataagagata gcagaggaaa aagaaaaaca
2461 tttcctctta taacttctga agtaatttgt aaaaaagatt tgtagagtca atcatgtgtt
2521 taaattattt tatcacaaac ttaacatgga agatattcct ttttaacttt gtggtaactt
2581 ctttgaagtt atttagaaat atcctttgga acaattattt tattgtctaa taaatattga
2641 cttctcttga attattttgc agactagtga gtctgtaaca taagtattaa tcacctccac
2701 tcatattaaa gtgatcatta agaatccaga agctggcttc tgcatttgct cagttatact
2761 tttaatggta gtatgttttt aggtggaata aattaatatg tgattggttt caaggaaatg
2821 tactctatta tgtaatactt ccattttata agatgcccgt ttctaataca atgtgtgtag
2881 gaattatttg tatgtatgag gtatgattgt aaagattgag cattggaagg ggtatcagag
2941 accatgtagt tcaactttcc actcaaagta agatttatga attatttaaa tgatagttgt
3001 tacttggaac agccacttga gaggctctct tggtattgtt tggaattgtt ttaaagtcag
3061 tttgagtctc acaagaaggt aagtagagtt tcttaatagt cacaacttaa tttgaaccac
3121 aagtatccag cttaatcacg tatcttactc acgataccac tggtccagat gagtttaggt
3181 aattttcaaa cattaaatcc aacttcaacg gaaacaaata cactcaaggg aagttatttt
3241 taaaaaggta ctctgcatgt tcccgcagta atgttctgca caacagtatt gtaattgtaa
3301 tggaatcata acctgctaac tagtttgctt taatatggct tgtaattctt gacatttttc
3361 ttaaaattaa aacgaatttt tattttgaat ttaaaaaaaa aaaaaaa
//