LOCUS BC028733 3194 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens PTK2 protein tyrosine kinase 2, mRNA (cDNA clone
MGC:33483 IMAGE:4812915), complete cds.
ACCESSION BC028733
VERSION BC028733.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3194)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3194)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 25, 2003 this sequence version replaced BC028733.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 46 Row: d Column: 12.
FEATURES Location/Qualifiers
source 1..3194
/db_xref="H-InvDB:HIT000050961"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:33483 IMAGE:4812915"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3194
/gene="PTK2"
/gene_synonym="FADK"
/gene_synonym="FAK"
/gene_synonym="FAK1"
/gene_synonym="pp125FAK"
/db_xref="GeneID:5747"
/db_xref="MIM:600758"
CDS 75..2117
/gene="PTK2"
/gene_synonym="FADK"
/gene_synonym="FAK"
/gene_synonym="FAK1"
/gene_synonym="pp125FAK"
/codon_start=1
/product="PTK2 protein"
/protein_id="AAH28733.1"
/db_xref="GeneID:5747"
/db_xref="MIM:600758"
/translation="MKYQEVRCLTSFNISVSFPAETDDYAEIIDEEDTYTMPSTRDYE
IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALT
MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLST
ALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMA
PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCP
PTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSG
GSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQ
ASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEED
QRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPG
APGHLGSLASLSSPADSYNEGVKLKPQEISPPPTANLDRSNDKVYENVTGLVKAVIEM
SSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGE
LINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRRH"
BASE COUNT 955 a 675 c 715 g 849 t
ORIGIN
1 tggagtaata gtgttttaag aatatttcag cgtagtagag gatttaagca gatcgctttg
61 cctactttaa ttatatgaaa taccaggagg tcagatgttt aacctctttc aacatatctg
121 tttcttttcc tgcagaaaca gatgattatg ctgagattat agatgaagaa gatacttaca
181 ccatgccctc aaccagggat tatgagattc aaagagaaag aatagaactt ggacgatgta
241 ttggagaagg ccaatttgga gatgtacatc aaggcattta tatgagtcca gagaatccag
301 ctttggcggt tgcaattaaa acatgtaaaa actgtacttc ggacagcgtg agagagaaat
361 ttcttcaaga agccttaaca atgcgtcagt ttgaccatcc tcatattgtg aagctgattg
421 gagtcatcac agagaatcct gtctggataa tcatggagct gtgcacactt ggagagctga
481 ggtcattttt gcaagtaagg aaatacagtt tggatctagc atctttgatc ctgtatgcct
541 atcagcttag tacagctctt gcatatctag agagcaaaag atttgtacac agggacattg
601 ctgctcggaa tgttctggtg tcctcaaatg attgtgtaaa attaggagac tttggattat
661 cccgatatat ggaagatagt acttactaca aagcttccaa aggaaaattg cctattaaat
721 ggatggctcc agagtcaatc aattttcgac gttttacctc agctagtgac gtatggatgt
781 ttggtgtgtg tatgtgggag atactgatgc atggtgtgaa gccttttcaa ggagtgaaga
841 acaatgatgt aatcggtcga attgaaaatg gggaaagatt accaatgcct ccaaattgtc
901 ctcctaccct ctacagcctt atgacgaaat gctgggccta tgaccccagc aggcggccca
961 ggtttactga acttaaagct cagctcagca caatcctgga ggaagagaag gctcagcaag
1021 aagagcgcat gaggatggag tccagaagac aggccacagt gtcctgggac tccggagggt
1081 ctgatgaagc accgcccaag cccagcagac cgggttatcc cagtccgagg tccagcgaag
1141 gattttatcc cagcccacag cacatggtac aaaccaatca ttaccaggtt tctggctacc
1201 ctggttcaca tggaatcaca gccatggctg gcagcatcta tccaggtcag gcatctcttt
1261 tggaccaaac agattcatgg aatcatagac ctcaggagat agcaatgtgg cagcccaatg
1321 tggaggactc tacagtattg gacctgcgag ggattgggca agtgttgcca acccatctga
1381 tggaagagcg tctaatccga cagcaacagg aaatggaaga agatcagcgc tggctggaaa
1441 aagaggaaag atttctgaaa cctgatgtga gactctctcg aggcagtatt gacagggagg
1501 atggaagtct tcagggtccg attggaaacc aacatatata tcagcctgtg ggtaaaccag
1561 atcctgcagc tccaccaaag aaaccgcctc gccctggagc tcccggtcat ctgggaagcc
1621 ttgccagcct cagcagccct gctgacagct acaacgaggg tgtcaagctt aagccccagg
1681 aaatcagccc ccctcctact gccaacctgg accggtcgaa tgataaggtg tacgagaatg
1741 tgacgggcct ggtgaaagct gtcatcgaga tgtccagtaa aatccagcca gccccaccag
1801 aggagtatgt ccctatggtg aaggaagtcg gcttggccct gaggacatta ttggccactg
1861 tggatgagac cattcccctc ctaccagcca gcacccaccg agagattgag atggcacaga
1921 agctattgaa ctctgacctg ggtgagctca tcaacaagat gaaactggcc cagcagtatg
1981 tcatgaccag cctccagcaa gagtacaaaa agcaaatgct gactgctgct cacgccctgg
2041 ctgtggatgc caaaaactta ctcgatgtca ttgaccaagc aagactgaaa atgcttgggc
2101 agacgagacg acactgagcc tcccctagga gcacgtcttg ctaccctctt ttgaagatgt
2161 tctctagcct tccaccagca gcgaggaatt aaccctgtgt cctcagtcgc cagcacttac
2221 agctccaact tttttgaatg accatctggt tgaaaaatct ttctcatata agtttaacca
2281 cactttgatt tgggttcatt ttttgttttg tttttttcaa tcatgatatt cagaaaaatc
2341 caggatccaa aatgtggcgt ttttctaaga atgaaaatta tatgtaagct tttaagcatc
2401 atgaagaaca atttatgttc acattaagat acgttctaaa gggggatggc caaggggtga
2461 catcttaatt cctaaactac cttagctgca tagtggaaga ggagagcatg aagcaaagaa
2521 ttccaggaaa cccaagaggc tgagaattct tttgtctacc atagaattat tatccagact
2581 ggaatttttg tttgttagaa cacccttcag ttgcaatatg ctaatcccac tttacaaaga
2641 atataaaagc tatattttga agacttgagt tatttcagaa aaaactacag ccctttttgt
2701 cttacctgcc ttttactttc gtgtggatat gtgaagcatt gggtcgggaa ctagctgtag
2761 aacacaacta aaaactcatg tcttttttca cagaataatg tgccagtttt ttgtagcaat
2821 gttatttctc ttggaagcag aaatgctttg taccagagca cctccaaact gcattgagga
2881 gaagttccag aaccatcccc tttttccatt tttatataat ttataaagaa agattaaagc
2941 catgttgact attttacagc cactggagtt aactaaccct tccttgtatc tgtcttccca
3001 ggagagaatg aagcaaaaca ggaatttggt tttcttttga tgtccagtta caccatccat
3061 tctgttaatt ttgaaaaaat ataccctccc tttagtttgt tgggggatat aaattattct
3121 caggaagaat ataatgaact gtacagttac tttgacctat taaaaaggtg ttaccagtaa
3181 aaaaaaaaaa aaaa
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