LOCUS BC028164 2331 bp mRNA linear HUM 01-FEB-2005
DEFINITION Homo sapiens tyrosine kinase, non-receptor, 2, mRNA (cDNA clone
IMAGE:5246061), complete cds.
ACCESSION BC028164
VERSION BC028164.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2331)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2331)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 62 Row: n Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..2331
/db_xref="H-InvDB:HIT000040471"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5246061"
/tissue_type="Brain, fetal, whole pooled"
/clone_lib="NIH_MGC_121"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2331
/gene="TNK2"
/gene_synonym="ACK"
/gene_synonym="ACK1"
/gene_synonym="p21cdc42Hs"
/db_xref="GeneID:10188"
/db_xref="MIM:606994"
CDS 58..1644
/gene="TNK2"
/gene_synonym="ACK"
/gene_synonym="ACK1"
/gene_synonym="p21cdc42Hs"
/codon_start=1
/product="TNK2 protein"
/protein_id="AAH28164.1"
/db_xref="GeneID:10188"
/db_xref="MIM:606994"
/translation="MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNE
DLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTS
PAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCL
KPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLR
KHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRA
LPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGL
NGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTD
MRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLS
AQDISQPLQNSFIHTGHGDSDPRHCWGFPDRIDECPFSAFSPGHPPAETCGQVLWTGR
REACASDPRLHPVSSRTKGL"
BASE COUNT 434 a 767 c 737 g 393 t
ORIGIN
1 cgcggagccg gctgagcgca gggccgagct gcggggcaga ggctgggagg cggcagaatg
61 cagccagagg agggcacagg ctggctgctg gagctgctgt ccgaggtgca gctgcaacag
121 tacttcctgc ggctccgaga cgacctcaac gtcacccgcc tgtcccactt tgagtacgtc
181 aagaatgagg acctggagaa gatcggcatg ggtcggcctg gccagcggcg gctgtgggag
241 gctgtgaaga ggaggaaggc cttgtgcaaa cgcaagtcgt ggatgagtaa ggtgttcagt
301 ggaaagcgac tggaggctga gttcccacct catcactctc agagcacctt ccggaagacc
361 tcgcccgccc ctgggggccc agcaggggag gggcccctgc agagcctcac ctgcctcatt
421 ggggagaagg acctgcgcct cctggagaag ctgggtgatg gttcctttgg cgtggtgcgc
481 aggggcgagt gggacgcgcc ctcagggaag acggtgagtg tggctgtgaa gtgcctgaag
541 cccgatgtcc tgagccagcc agaagccatg gacgacttca tccgggaggt caatgccatg
601 cactcgctcg accaccgaaa cctcatccgc ctctacgggg tggtgctcac gccgcccatg
661 aagatggtga cagagctggc acctctggga tcgttgttgg accggctacg taagcaccag
721 ggccacttcc tcctggggac tctgagccgc tacgctgtgc aggtggctga gggcatgggc
781 tacctggagt ccaagcgctt tattcaccgt gacctggctg cccgcaatct gctgttggct
841 acccgcgacc tggtcaagat cggggacttt gggctgatgc gagcactacc tcagaatgac
901 gaccattacg tcatgcagga acatcgcaag gtgcccttcg cctggtgtgc ccccgagagc
961 ctgaagacac gtaccttctc ccatgccagc gacacctgga tgttcggggt gacactgtgg
1021 gaaatgttca cctacggcca ggagccctgg atcggcctca acggcagtca gatcctgcat
1081 aagatcgaca aggaggggga gcggctgccc cggcccgagg actgtcccca ggacatctac
1141 aacgtcatgg tccagtgctg ggctcacaag ccagaggaca gacccacgtt tgtggccctg
1201 cgggacttcc tgctggaggc ccagcccaca gacatgcggg cccttcagga ctttgaggaa
1261 ccggacaagc tgcacatcca gatgaatgat gtcatcaccg tcatcgaggg aagggccgag
1321 aactactggt ggcgtggcca gaacacacgg acgctgtgtg tggggccctt ccctcgcaac
1381 gtggtgacct ccgtggccgg cctgtcggcc caggacatca gccagcccct gcagaacagc
1441 ttcatccaca cagggcatgg cgacagtgac ccccgccact gctggggctt cccggacagg
1501 attgacgagt gtcctttctc tgccttctct ccaggacacc ccccagctga gacgtgcggt
1561 caggttctgt ggactgggag gcgggaggcc tgtgcttcag acccaagact acacccggtt
1621 tcctccagga cgaaggggct ctgatgagat tctgccaccc ctccacacgc ttcccctgct
1681 ctcttgaccc agctctctcc cccacagact gtatctggga aaccccatgg acccccccga
1741 cctcctgagc gtggaactga gcacctcccg gcccccccag catctaggag gggtgaaaag
1801 ggagcctcca cctcgcccac ctcagcctgc cttcttcact cagaaaccaa cctatgaccc
1861 tgtgagcgag gaccaagacc ccttgtccag cgacttcaag aggctgggcc tgcggaagcc
1921 aggcctgccc cgagggctgt ggctggcgaa gccctcggcg cgggtgccgg gcaccaaggc
1981 cagccgaggc agcggggctg aggtcacgct catcgacttc ggtgaggagc ccgtggtccc
2041 ggccctacgg ccctgcgcgc cctccctggc gcagctggcc atggacgcct gctccctgct
2101 ggacgagacc ccgcctcaga gccccacgcg ggcactgccc cggcccctgc accccacgcc
2161 tgtggtggac tgggacgcac gcccgctgcc ccccccgccc gcctatgacg acgtggccca
2221 ggatgaggat gactttgaga tctgctccat caacagcacc ctcgtgggcg cgggggtccc
2281 tgccgggccc agccagggcc agaccaacta cgcctttgtg cctgagcagg c
//