LOCUS BC027994 2308 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens beta-transducin repeat containing, mRNA (cDNA clone
MGC:40028 IMAGE:5180993), complete cds.
ACCESSION BC027994
VERSION BC027994.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2308)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2308)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 62 Row: e Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 37039615.
FEATURES Location/Qualifiers
source 1..2308
/db_xref="H-InvDB:HIT000040397"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:40028 IMAGE:5180993"
/tissue_type="Brain, Lung, Testis, adult, pooled whole"
/clone_lib="NIH_MGC_115"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2308
/gene="BTRC"
/gene_synonym="BETA-TRCP"
/gene_synonym="betaTrCP"
/gene_synonym="bTrCP"
/gene_synonym="bTrCP1"
/gene_synonym="FBW1A"
/gene_synonym="FBXW1A"
/gene_synonym="FWD1"
/gene_synonym="MGC4643"
/db_xref="GeneID:8945"
/db_xref="HGNC:HGNC:1144"
/db_xref="MIM:603482"
CDS 38..1855
/gene="BTRC"
/gene_synonym="BETA-TRCP"
/gene_synonym="betaTrCP"
/gene_synonym="bTrCP"
/gene_synonym="bTrCP1"
/gene_synonym="FBW1A"
/gene_synonym="FBXW1A"
/gene_synonym="FWD1"
/gene_synonym="MGC4643"
/codon_start=1
/product="beta-transducin repeat containing"
/protein_id="AAH27994.1"
/db_xref="GeneID:8945"
/db_xref="HGNC:HGNC:1144"
/db_xref="MIM:603482"
/translation="MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPG
TGALTAFQNSSEREDCNNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKT
ENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQM
CHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRV
TSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKII
QDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLE
CKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFN
NGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKV
WNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEEL
VRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEF
QIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTYTYISR"
BASE COUNT 719 a 493 c 530 g 566 t
ORIGIN
1 gccccggcgg agagcggacc cagtggcctc ggcgattatg gacccggccg aggcggtgct
61 gcaagagaag gcactcaagt ttatgtgctc tatgcccagg tctctgtggc tgggctgctc
121 cagcctggcg gacagcatgc cttcgctgcg atgcctgtat aacccaggga ctggcgcact
181 cacagctttc cagaattcct cagagagaga agactgtaat aatggcgaac cccctaggaa
241 gataatacca gagaagaatt cacttagaca gacatacaac agctgtgcca gactctgctt
301 aaaccaagaa acagtatgtt tagcaagcac tgctatgaag actgagaatt gtgtggccaa
361 aacaaaactt gccaatggca cttccagtat gattgtgccc aagcaacgga aactctcagc
421 aagctatgaa aaggaaaagg aactgtgtgt caaatacttt gagcagtggt cagagtcaga
481 tcaagtggaa tttgtggaac atcttatatc ccaaatgtgt cattaccaac atgggcacat
541 aaactcgtat cttaaaccta tgttgcagag agatttcata actgctctgc cagctcgggg
601 attggatcat attgctgaga acattctgtc atacctggat gccaaatcac tatgtgctgc
661 tgaacttgtg tgcaaggaat ggtaccgagt gacctctgat ggcatgctgt ggaagaagct
721 tatcgagaga atggtcagga cagattctct gtggagaggc ctggcagaac gaagaggatg
781 gggacagtat ttattcaaaa acaaacctcc tgacgggaat gctcctccca actcttttta
841 tagagcactt tatcctaaaa ttatacaaga cattgagaca atagaatcta attggagatg
901 tggaagacat agtttacaga gaattcactg ccgaagtgaa acaagcaaag gagtttactg
961 tttacagtat gatgatcaga aaatagtaag cggccttcga gacaacacaa tcaagatctg
1021 ggataaaaac acattggaat gcaagcgaat tctcacaggc catacaggtt cagtcctctg
1081 tctccagtat gatgagagag tgatcataac aggatcatcg gattccacgg tcagagtgtg
1141 ggatgtaaat acaggtgaaa tgctaaacac gttgattcac cattgtgaag cagttctgca
1201 cttgcgtttc aataatggca tgatggtgac ctgctccaaa gatcgttcca ttgctgtatg
1261 ggatatggcc tccccaactg acattaccct ccggagggtg ctggtcggac accgagctgc
1321 tgtcaatgtt gtagactttg atgacaagta cattgtttct gcatctgggg atagaactat
1381 aaaggtatgg aacacaagta cttgtgaatt tgtaaggacc ttaaatggac acaaacgagg
1441 cattgcctgt ttgcagtaca gggacaggct ggtagtgagt ggctcatctg acaacactat
1501 cagattatgg gacatagaat gtggtgcatg tttacgagtg ttagaaggcc atgaggaatt
1561 ggtgcgttgt attcgatttg ataacaagag gatagtcagt ggggcctatg atggaaaaat
1621 taaagtgtgg gatcttgtgg ctgctttgga cccccgtgct cctgcaggga cactctgtct
1681 acggaccctt gtggagcatt ccggaagagt ttttcgacta cagtttgatg aattccagat
1741 tgtcagtagt tcacatgatg acacaatcct catctgggac ttcctaaatg atccagctgc
1801 ccaagctgaa cccccccgtt ccccttctcg aacatacacc tacatctcca gataaataac
1861 catacactga cctcatactt gcccaggacc cattaaagtt gcggtattta acgtatctgc
1921 caataccagg atgagcaaca acagtaacaa tcaaactact gcccagtttc cctggactag
1981 ccgaggagca gggctttgag actcctgttg ggacacagtt ggtctgcagt cggcccagga
2041 cggtctactc agcacaactg actgcttcag tgctgctatc agaagatgtc ttctatcttt
2101 tgtgaatgat tggaactttt aaacctcccc tcctctcctc ctttcacctc tgcacctagt
2161 tttttcccat tggttccaga caaaggtgac ttataaatat atttagtgtt ttgccagaaa
2221 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2281 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//