LOCUS BC027974 1047 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens granzyme H (cathepsin G-like 2, protein h-CCPX), mRNA
(cDNA clone MGC:34849 IMAGE:5229314), complete cds.
ACCESSION BC027974
VERSION BC027974.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1047)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1047)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: p Column: 16.
FEATURES Location/Qualifiers
source 1..1047
/db_xref="H-InvDB:HIT000040387"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34849 IMAGE:5229314"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1047
/gene="GZMH"
/gene_synonym="CCP-X"
/gene_synonym="CGL-2"
/gene_synonym="CSP-C"
/gene_synonym="CTLA1"
/db_xref="GeneID:2999"
/db_xref="HGNC:HGNC:4710"
/db_xref="MIM:116831"
CDS 46..786
/gene="GZMH"
/gene_synonym="CCP-X"
/gene_synonym="CGL-2"
/gene_synonym="CSP-C"
/gene_synonym="CTLA1"
/codon_start=1
/product="granzyme H (cathepsin G-like 2, protein h-CCPX)"
/protein_id="AAH27974.1"
/db_xref="GeneID:2999"
/db_xref="HGNC:HGNC:4710"
/db_xref="MIM:116831"
/translation="MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEK
SRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNP
KNFSNDIMLLQLERKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQ
EVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSY
GNKKGTPPGVYIKVSHFLPWIKRTMKRL"
BASE COUNT 374 a 242 c 251 g 180 t
ORIGIN
1 ggagtcaaca ccaacagctc tgacctgggc agccttcctg agaaaatgca gccattcctc
61 ctcctgttgg cctttcttct gacccctggg gctgggacag aggagatcat cgggggccat
121 gaggccaagc cccactcccg cccctacatg gcctttgttc agtttctgca agagaagagt
181 cggaagaggt gtggcggcat cctagtgaga aaggactttg tgctgacagc tgctcactgc
241 cagggaagct ccataaatgt caccttgggg gcccacaata tcaaggaaca ggagcggacc
301 cagcagttta tccctgtgaa aagacccatc ccccatccag cctataatcc taagaacttc
361 tccaacgaca tcatgctact gcagctggag agaaaggcca agtggaccac agctgtgcgg
421 cctctcaggc tacctagcag caaggcccag gtgaagccag ggcagctgtg cagtgtggct
481 ggctggggtt atgtctcaat gagcacttta gcaaccacac tgcaggaagt gttgctgaca
541 gtgcagaagg actgccagtg tgaacgtctc ttccatggca attacagcag agccactgag
601 atttgtgtgg gggatccaaa gaagacacag accggtttca agggggactc cggggggccc
661 ctcgtgtgta aggacgtagc ccaaggtatt ctctcctatg gaaacaaaaa agggacacct
721 ccaggagtct acatcaaggt ctcacacttc ctgccctgga taaagagaac aatgaagcgc
781 ctctaacagc aggcatgaga ctaaccttcc tctgggcctg accatctctg ggacagaggc
841 aagaatcccc aaggggtggg cagtcagggt tgcaggactg taataaatgg atctctggtg
901 tagaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
961 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1021 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//