LOCUS BC027883 1644 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens left-right determination factor 1, mRNA (cDNA clone
MGC:34249 IMAGE:5221120), complete cds.
ACCESSION BC027883
VERSION BC027883.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1644)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1644)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: k Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27436943.
FEATURES Location/Qualifiers
source 1..1644
/db_xref="H-InvDB:HIT000040334"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34249 IMAGE:5221120"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1644
/gene="LEFTY1"
/gene_synonym="LEFTYB"
/db_xref="GeneID:10637"
/db_xref="HGNC:HGNC:6552"
/db_xref="MIM:603037"
CDS 68..1168
/gene="LEFTY1"
/gene_synonym="LEFTYB"
/codon_start=1
/product="left-right determination factor 1"
/protein_id="AAH27883.1"
/db_xref="GeneID:10637"
/db_xref="HGNC:HGNC:6552"
/db_xref="MIM:603037"
/translation="MQPLWLCWALWVLPLASPGAALTGEQLLGSLLRQLQLKEVPTLD
RADMEELVIPTHVRAQYVALLQRSHGDRSRGKRFSQSFREVAGRFLALEASTHLLVFG
MEQRLPPNSELVQAVLRLFQEPVPKAALHRHGRLSPRSARARVTVEWLRVRDDGSNRT
SLIDSRLVSVHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASGAHKL
VRFASQGAPAGLGEPQLELHTLDLGDYGAQGDCDPEAPMTEGTRCCRQEMYIDLQGMK
WAENWVLEPPGFLAYECVGTCRQPPEALAFKWPFLGPRQCIASETDSLPMIVSIKEGG
RTRPQVVSLPNMRVQKCSCASDGALVPRRLQP"
BASE COUNT 323 a 496 c 506 g 319 t
ORIGIN
1 tgagaccctc ctgcagcctt ctcaagggac agccccactc tgcctcttgc tcctccaggg
61 cagcaccatg cagcccctgt ggctctgctg ggcactctgg gtgttgcccc tggccagccc
121 cggggccgcc ctgaccgggg agcagctcct gggcagcctg ctgcggcagc tgcagctcaa
181 agaggtgccc accctggaca gggccgacat ggaggagctg gtcatcccca cccacgtgag
241 ggcccagtac gtggccctgc tgcagcgcag ccacggggac cgctcccgcg gaaagaggtt
301 cagccagagc ttccgagagg tggccggcag gttcctggcg ttggaggcca gcacacacct
361 gctggtgttc ggcatggagc agcggctgcc gcccaacagc gagctggtgc aggccgtgct
421 gcggctcttc caggagccgg tccccaaggc cgcgctgcac aggcacgggc ggctgtcccc
481 gcgcagcgcc cgggcccggg tgaccgtcga gtggctgcgc gtccgcgacg acggctccaa
541 ccgcacctcc ctcatcgact ccaggctggt gtccgtccac gagagcggct ggaaggcctt
601 cgacgtgacc gaggccgtga acttctggca gcagctgagc cggccccggc agccgctgct
661 gctacaggtg tcggtgcaga gggagcatct gggcccgctg gcgtccggcg cccacaagct
721 ggtccgcttt gcctcgcagg gggcgccagc cgggcttggg gagccccagc tggagctgca
781 caccctggac cttggggact atggagctca gggcgactgt gaccctgaag caccaatgac
841 cgagggcacc cgctgctgcc gccaggagat gtacattgac ctgcagggga tgaagtgggc
901 cgagaactgg gtgctggagc ccccgggctt cctggcttat gagtgtgtgg gcacctgccg
961 gcagcccccg gaggccctgg ccttcaagtg gccgtttctg gggcctcgac agtgcatcgc
1021 ctcggagact gactcgctgc ccatgatcgt cagcatcaag gagggaggca ggaccaggcc
1081 ccaggtggtc agcctgccca acatgagggt gcagaagtgc agctgtgcct cggatggtgc
1141 gctcgtgcca aggaggctcc agccataggc gcctagtgta gccatcgagg gacttgactt
1201 gtgtgtgttt ctgaagtgtt cgagggtacc aggagagctg gcgatgactg aactgctgat
1261 ggacaaatgc tctgtgctct ctagtgagcc ctgaatttgc ttcctctgac aagttacctc
1321 acctaatttt tgcttctcag gaatgagaat ctttggccac tggagagccc ttgctcagtt
1381 ttctctattc ttattattca ctgcactata ttctaagcac ttacatgtgg agatactgta
1441 acttgagggc agaaagccca atgtgtcatt gtttacttgt cctgtcactg gatctgggct
1501 aaagtcctcc accaccactc tggacctaag acctggggtt aagtgtgggt tgtgcatccc
1561 caatccagat aataaagact ttgtaaaaca tgaataaaac acattttatt ctaaaaaaaa
1621 aaaaaaaaaa aaaaaaaaaa aaaa
//