LOCUS BC026002 1611 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens GRB2-related adaptor protein 2, mRNA (cDNA clone
MGC:27357 IMAGE:4672797), complete cds.
ACCESSION BC026002
VERSION BC026002.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1611)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1611)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (18-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 38 Row: i Column: 15.
FEATURES Location/Qualifiers
source 1..1611
/db_xref="H-InvDB:HIT000040062"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:27357 IMAGE:4672797"
/tissue_type="Lung, mucoepidermoid carcinoma"
/clone_lib="NIH_MGC_59"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1611
/gene="GRAP2"
/gene_synonym="GADS"
/gene_synonym="GRAP-2"
/gene_synonym="GRB2L"
/gene_synonym="GRBLG"
/gene_synonym="GrbX"
/gene_synonym="Grf40"
/gene_synonym="GRID"
/gene_synonym="GRPL"
/gene_synonym="Mona"
/gene_synonym="P38"
/db_xref="GeneID:9402"
/db_xref="MIM:604518"
CDS 260..1252
/gene="GRAP2"
/gene_synonym="GADS"
/gene_synonym="GRAP-2"
/gene_synonym="GRB2L"
/gene_synonym="GRBLG"
/gene_synonym="GrbX"
/gene_synonym="Grf40"
/gene_synonym="GRID"
/gene_synonym="GRPL"
/gene_synonym="Mona"
/gene_synonym="P38"
/codon_start=1
/product="GRAP2 protein"
/protein_id="AAH26002.1"
/db_xref="GeneID:9402"
/db_xref="MIM:604518"
/translation="MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEG
YVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDV
QHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSL
DRRSQGGPHLSGAVGEEIRPSMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPP
QQRYLQHHHFHQERRGGSLDINDGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWA
RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMTR"
misc_feature 266..421
/gene="GRAP2"
/gene_synonym="GADS"
/gene_synonym="GRAP-2"
/gene_synonym="GRB2L"
/gene_synonym="GRBLG"
/gene_synonym="GrbX"
/gene_synonym="Grf40"
/gene_synonym="GRID"
/gene_synonym="GRPL"
/gene_synonym="Mona"
/gene_synonym="P38"
/note="SH3; Region: Src homology 3 domains"
/db_xref="CDD:smart00326"
misc_feature 431..673
/gene="GRAP2"
/gene_synonym="GADS"
/gene_synonym="GRAP-2"
/gene_synonym="GRB2L"
/gene_synonym="GRBLG"
/gene_synonym="GrbX"
/gene_synonym="Grf40"
/gene_synonym="GRID"
/gene_synonym="GRPL"
/gene_synonym="Mona"
/gene_synonym="P38"
/note="SH2; Region: Src homology 2 domains"
/db_xref="CDD:smart00252"
misc_feature 1085..1243
/gene="GRAP2"
/gene_synonym="GADS"
/gene_synonym="GRAP-2"
/gene_synonym="GRB2L"
/gene_synonym="GRBLG"
/gene_synonym="GrbX"
/gene_synonym="Grf40"
/gene_synonym="GRID"
/gene_synonym="GRPL"
/gene_synonym="Mona"
/gene_synonym="P38"
/note="SH3; Region: Src homology 3 domains"
/db_xref="CDD:smart00326"
BASE COUNT 441 a 418 c 421 g 331 t
ORIGIN
1 ggggcttcat ttcctgttcc tggcatctgg ggattccgag aatgatccca ggacctagat
61 cctatagatt ccggcagctc ttcctgcaaa cacaagccct tgttgtgtgc ctgagccttg
121 ctctccggcc tggagacatc catctgccca ctctcctagg aactgctgat taccaggaag
181 caccatcggc tctgctgccc tccccctggc agagaggcac aatgaccaca ttatttctct
241 tccagcttca cgttacagca tggaagctgt tgccaagttt gatttcactg cttcaggtga
301 ggatgaactg agctttcaca ctggagatgt tttgaagatt ttaagtaacc aagaggagtg
361 gtttaaggcg gagcttggga gccaggaagg atatgtgccc aagaatttca tagacatcca
421 gtttcccaaa tggtttcacg aaggcctctc tcgacaccag gcagagaact tactcatggg
481 caaggaggtt ggcttcttca tcatccgggc cagccagagc tccccagggg acttctccat
541 ctctgtcagg catgaggatg acgttcaaca cttcaaggtc atgcgagaca acaagggtaa
601 ttactttctg tggactgaga agtttccatc cctaaataag ctggtagact actacaggac
661 aaattccatc tccagacaga agcagatctt ccttagagac agaacccgag aagaccaggg
721 tcaccggggc aacagcctgg accggaggtc ccagggaggc ccacacctca gtggggctgt
781 gggagaagaa atccgacctt cgatgaaccg gaagctgtcg gatcaccccc cgacccttcc
841 cctgcagcag caccagcacc agccacagcc tccgcaatat gccccagcgc cccagcagct
901 gcagcagccc ccacagcagc gatatctgca gcaccaccat ttccaccagg aacgccgagg
961 aggcagcctt gacataaatg atgggcattg tggcaccggc ttgggcagtg aaatgaatgc
1021 ggccctcatg catcggagac acacagaccc agtgcagctc caggcggcag ggcgagtgcg
1081 gtgggcccgg gcgctgtatg actttgaggc cctggaggat gacgagctgg ggttccacag
1141 cggggaggtg gtggaggtcc tggatagctc caacccatcc tggtggaccg gccgcctgca
1201 caacaagctg ggcctcttcc ctgccaacta cgtggcaccc atgacccgat aaactcttca
1261 ggggacagaa gctttttgtc tggagctgcc cacaagaaag agggcaagga aaaaaggctg
1321 gactccatga ctatatatac atacatctat ctacatctgc ctgtgtacac acacaacttt
1381 ttatactagt aatttattgg caattgggct ggtaattagt tgatgcaaaa gggaactcag
1441 gtggagaata atattgacac ttgcttttct gcccccctca ggggtgtgtg gaaggcagtg
1501 ggggagttgg gaggggggca gggaaatgaa atggagtttt gtcctggcaa aaaaaaaaaa
1561 aaaaaaaaaa aaaaaaaaaa aagaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//