LOCUS BC025958 1228 bp mRNA linear HUM 24-FEB-2004
DEFINITION Homo sapiens cerebral cavernous malformation 2, mRNA (cDNA clone
IMAGE:4587331), partial cds.
ACCESSION BC025958
VERSION BC025958.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1228)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1228)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (18-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 42 Row: e Column: 20.
FEATURES Location/Qualifiers
source 1..1228
/db_xref="H-InvDB:HIT000091136"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4587331"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1228
/gene="CCM2"
/gene_synonym="C7orf22"
/gene_synonym="MGC4067"
/gene_synonym="MGC4607"
/db_xref="GeneID:83605"
/db_xref="MIM:607929"
CDS <1..813
/gene="CCM2"
/gene_synonym="C7orf22"
/gene_synonym="MGC4067"
/gene_synonym="MGC4607"
/codon_start=1
/product="CCM2 protein"
/protein_id="AAH25958.1"
/db_xref="GeneID:83605"
/db_xref="MIM:607929"
/translation="RGLSAGSLSESAVGPVEACCLVILAAESKVAAEELCCLLGQVFQ
VVYTESTIDFLDRAIFDGASTPTHHLSLHSDDSSTKVDIKETYEVEASTFCFPESVDV
GGASPHSKTISESELSASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEF
CINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLETIGVKDGRGIITDSFGRHRRAL
STTSSSTTNGNRATGSSDDRSAPSEGDEWDRMISDISSDIEALGCSMDQDSA"
BASE COUNT 267 a 351 c 379 g 231 t
ORIGIN
1 agaggcctca gtgcaggctc cctgtcggag agtgcagttg ggcccgtgga ggcatgctgc
61 ctggtcatcc tggctgcaga gagcaaggtc gctgcggagg agctttgctg tctgctaggc
121 caggtcttcc aggttgttta cacggagtcc accatcgact ttctggacag agcgatattt
181 gatggggcct ctaccccgac ccaccacctg tccctgcaca gcgatgactc ttctacaaaa
241 gtggacatta aggagaccta cgaggtggaa gccagcactt tctgcttccc tgaatctgtg
301 gatgtgggtg gtgcatcacc ccacagcaag accatcagtg agagcgagct gagcgccagc
361 gccactgagc tgctgcagga ctacatgctg acgctgcgca ccaagctgtc atcacaggag
421 atccagcagt ttgcagcact gctgcacgag taccgcaatg gggcctctat ccacgagttc
481 tgcatcaacc tgcggcagct ctacggggac agccgcaagt tcctgctgct tggtctgagg
541 cccttcatcc ctgagaagga cagccagcac ttcgagaact tcctggagac cattggcgtg
601 aaggatggcc gcggcatcat cactgacagc tttggcaggc accggcgggc cctgagcacc
661 acatccagtt ccaccaccaa tgggaacagg gccacgggca gctctgatga ccggtcggca
721 ccctcagagg gggatgagtg ggaccgcatg atctcggaca tcagcagcga cattgaggcg
781 ctgggctgca gcatggacca ggactcagca tgatggacag tggatggggg ggcacccaca
841 ccttccgcgc agtcgtcata ggccttccca gaaggagctg cccagacctg cgtgtcagcc
901 cttggtggtg gccagggaga ggcgcccggt gcagatggcc ccgggcggcc caggtcctct
961 actgtgaagg agcagggagc tgccgaggga cacgagcctc agtgcggggt ggaaggctct
1021 ttgccttgtc caccagggct cagccaagcc ctgcagtgtg tccccgctcg gggagggccc
1081 ggccgagcgg gcagggagag ccagtcctgt cggctgggcc cttggacggc tgtcagtttt
1141 gcacatgatg ttcctattgt aactctcaga gaccttaaaa agaagtttac tgcaatgtga
1201 ataatttaaa aaaaaaaaaa aaaaaaaa
//