LOCUS BC025953 1618 bp mRNA linear HUM 03-NOV-2005
DEFINITION Homo sapiens single immunoglobulin and toll-interleukin 1 receptor
(TIR) domain, mRNA (cDNA clone MGC:39141 IMAGE:3939162), complete
cds.
ACCESSION BC025953
VERSION BC025953.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1618)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1618)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (18-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 42 Row: b Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 11141876.
FEATURES Location/Qualifiers
source 1..1618
/db_xref="H-InvDB:HIT000040037"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:39141 IMAGE:3939162"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1618
/gene="SIGIRR"
/gene_synonym="TIR8"
/db_xref="GeneID:59307"
/db_xref="HGNC:HGNC:30575"
/db_xref="IMGT/GENE-DB:30575"
/db_xref="MIM:605478"
CDS 186..1418
/gene="SIGIRR"
/gene_synonym="TIR8"
/codon_start=1
/product="SIGIRR protein"
/protein_id="AAH25953.1"
/db_xref="GeneID:59307"
/db_xref="HGNC:HGNC:30575"
/db_xref="IMGT/GENE-DB:30575"
/db_xref="MIM:605478"
/translation="MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSL
PSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQN
ISFSSFTLQRAGPTSHVAAVLASLLVLLALLLAALLYVKCRLNVLLWYQDAYGEVEIN
DGKLYDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRAEPSADLLVNL
SRCRRLIVVLSDAFLSRAWCSHSFREGLCRLLELTRRPIFITFEGQRRDPAHPALRLL
RQHRHLVTLLLWRPGSVTPSSDFWKEVQLALPRKVRYRPVEGDPQTQLQDDKDPMLIL
RGRVPEGRALDSEVDPDPEGDLGVRGPVFGEPSAPPHTSGVSLGESRSSEVDVSDLGS
RNYSARTDFYCLVSKDDM"
BASE COUNT 292 a 532 c 498 g 296 t
ORIGIN
1 ggtgagtggc ggtcgccatc agacccgcga agcctctgac ctgtccaggt gccctgtcca
61 gctgactgca aggacagaga ggagtcctgc ccagctcttg gatcagtctg ctggccgagg
121 agcccggtgg agccaggggt gaccctggag cccagcctgc cccgaggagg ccccggctca
181 gagccatgcc aggtgtctgt gatagggccc ctgacttcct ctccccgtct gaagaccagg
241 tgctgaggcc tgccttgggc agctcagtgg ctctgaactg cacggcttgg gtagtctctg
301 ggccccactg ctccctgcct tcagtccagt ggctgaaaga cgggcttcca ttgggaattg
361 ggggccacta cagcctccac gagtactcct gggtcaaggc caacctgtca gaggtgcttg
421 tgtccagtgt cctgggggtc aacgtgacca gcactgaagt ctatggggcc ttcacctgct
481 ccatccagaa catcagcttc tcctccttca ctcttcagag agctggccct acaagccacg
541 tggctgcggt gctggcctcc ctcctggtcc tgctggccct gctgctggcc gccctgctct
601 atgtcaagtg ccgtctcaac gtgctgctct ggtaccagga cgcgtatggg gaggtggaga
661 taaacgacgg gaagctctac gacgcctacg tctcctacag cgactgcccc gaggaccgca
721 agttcgtgaa cttcatccta aagccgcagc tggagcggcg tcggggctac aagctcttcc
781 tggacgaccg cgacctcctg ccgcgcgctg agccctccgc cgacctcttg gtgaacctga
841 gccgctgccg acgcctcatc gtggtgcttt cggacgcctt cctgagccgg gcctggtgca
901 gccacagctt ccgggagggc ctgtgccggc tgctggagct cacccgcaga cccatcttca
961 tcaccttcga gggccagagg cgcgaccccg cgcacccggc gctccgcctg ctgcgccagc
1021 accgccacct ggtgaccttg ctgctctgga ggcccggctc cgtgactcct tcctccgatt
1081 tttggaaaga agtgcagctg gcgctgccgc ggaaggtgcg gtacaggccg gtggaaggag
1141 acccccagac gcagctgcag gacgacaagg accccatgct gattcttcga ggccgagtcc
1201 ctgagggccg ggccctggac tcagaggtgg acccggaccc tgagggcgac ctgggtgtcc
1261 gggggcctgt ttttggagag ccatcagctc caccgcacac cagtggggtc tcgctgggag
1321 agagccggag cagcgaagtg gacgtctcgg atctcggctc gcgaaactac agtgcccgca
1381 cagacttcta ctgcctggtg tccaaggatg atatgtagct cccaccccag agtgcaggat
1441 catagggaca gcgggggcca gggcagcggc gtcgctcctc tgctcaacag gaccacaacc
1501 cctgccagca gccctgggac cctgccagca gccctgggaa aaggctgtgg cctcagggcg
1561 cctcccagtg ccagaaaata aagtcctttt ggattctgaa aaaaaaaaaa aaaaaaaa
//