LOCUS BC025724 1780 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens retinol dehydrogenase 12 (all-trans/9-cis/11-cis),
mRNA (cDNA clone MGC:34672 IMAGE:5199154), complete cds.
ACCESSION BC025724
VERSION BC025724.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1780)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1780)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: a Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22748934.
FEATURES Location/Qualifiers
source 1..1780
/db_xref="H-InvDB:HIT000039990"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34672 IMAGE:5199154"
/tissue_type="Brain, adult, 6 pooled whole brains"
/clone_lib="NIH_MGC_114"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1780
/gene="RDH12"
/gene_synonym="FLJ30273"
/gene_synonym="LCA3"
/db_xref="GeneID:145226"
/db_xref="HGNC:HGNC:19977"
/db_xref="MIM:608830"
CDS 171..1121
/gene="RDH12"
/gene_synonym="FLJ30273"
/gene_synonym="LCA3"
/codon_start=1
/product="retinol dehydrogenase 12
(all-trans/9-cis/11-cis)"
/protein_id="AAH25724.1"
/db_xref="GeneID:145226"
/db_xref="HGNC:HGNC:19977"
/db_xref="MIM:608830"
/translation="MLVTLGLLTSFFSFLYMVAPSIRKFFAGGVCRTNVQLPGKVVVI
TGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDLSDT
KSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTYLLLE
QLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAKRL
QGTGVTTYAVHPGVVRSELVRHSSLLCLLWRLFSPFVKTAREGAQTSLHCALAEGLEP
LSGKYFSDCKRTWVSPRARNNKTAERLWNVSCELLGIRWE"
BASE COUNT 456 a 466 c 470 g 388 t
ORIGIN
1 ggattctggg ctctgctcag agtcaggctg ctgctcagca cccaggacgg agaggagcag
61 agaagcagca gaagcagcca agagctggag ccagaccagg aacctgagcc agagctgggg
121 ttgaagctgg agcagcagca aaagcaacag cagctacaga agttggaacg atgctggtca
181 ccttgggact gctcacctcc ttcttctcgt tcctgtatat ggtagctcca tccatcagga
241 agttctttgc tggtggagtg tgtagaacaa atgtgcagct tcctggcaag gtagtggtga
301 tcactggcgc caacacgggc attggcaagg agacggccag agagctcgct agccgaggag
361 cccgagtcta tattgcctgc agagatgtac tgaaggggga gtctgctgcc agtgaaatcc
421 gagtggatac aaagaactcc caggtgctgg tgcggaaatt ggacctatcc gacaccaaat
481 ctatccgagc ctttgctgag ggctttctgg cagaggaaaa gcagctccat attctgatca
541 acaatgcggg agtaatgatg tgtccatatt ccaagacagc tgatggcttt gaaacccacc
601 tgggagtcaa ccacctgggc cacttcctcc tcacctacct gctcctggag cagctaaagg
661 tgtctgcccc tgcacgggtg gttaatgtgt cctcggtggc tcaccacatt ggcaagattc
721 ccttccacga cctccagagc gagaagcgct acagcagggg ttttgcctat tgccacagca
781 agctggccaa tgtgcttttt actcgtgagc tggccaagag gctccaaggc accggggtca
841 ccacctacgc agtgcaccca ggcgtcgtcc gctctgagct ggtccggcac tcctccctgc
901 tctgcctgct ctggcggctc ttctccccct ttgtcaagac ggcacgggag ggggcgcaga
961 ccagcctgca ctgcgccctg gctgagggcc tggagcccct gagtggcaag tacttcagtg
1021 actgcaagag gacctgggtg tctccaaggg cccgaaataa caaaacagct gagcgcctat
1081 ggaatgtcag ctgtgagctt ctaggaatcc ggtgggagta gctggtggaa gagctgcagc
1141 tttatcaggc ccaatccatg ccataatgaa cagggaccaa ggagaaggcc aaccctaaag
1201 gattgtcctc ttggccagct ggtgctgcga atcctgcctg ctctgatcct cttgaccctt
1261 ctgggaatgt ttgcacacct gacactcttg tgagactggc ttatggcatg agttgtggac
1321 acctatagag tgttcttctc taagacctgg aaagtcagca accctctggg ggcagcagga
1381 ctgggcagat cccaggctgg gcatgggggt ggcagaagag cccgagaaat tgggtcagtt
1441 ccctcatcag caccagaggc tcagctgagg caagaagagc accatcactg cctatttcta
1501 ggggctatac actccaactc ttggttgatc tctttctttt taaaaatatt tgccaccacc
1561 ctggagtcta gaccaacaca caaagatcct ggctaaccct ggcctattta gattccttcc
1621 tctcacctgg accttcccat ttcaatcatg cagatggttt ctttttgtaa agagttccgt
1681 ttgcctttca atttttagag aaaataaaga ctgcattcat ctcaaaaaaa aaaaaaaaaa
1741 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
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