LOCUS BC025721 2673 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens EGF, latrophilin and seven transmembrane domain
containing 1, mRNA (cDNA clone MGC:34204 IMAGE:5229055), complete
cds.
ACCESSION BC025721
VERSION BC025721.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2673)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2673)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (06-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: o Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21359949.
FEATURES Location/Qualifiers
source 1..2673
/db_xref="H-InvDB:HIT000039987"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34204 IMAGE:5229055"
/tissue_type="Pancreas, Spleen, adult pooled"
/clone_lib="NIH_MGC_120"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2673
/gene="ELTD1"
/gene_synonym="ETL"
/db_xref="GeneID:64123"
CDS 275..2095
/gene="ELTD1"
/gene_synonym="ETL"
/codon_start=1
/product="ELTD1 protein"
/protein_id="AAH25721.1"
/db_xref="GeneID:64123"
/translation="MCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVCIAANINK
TLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTISAKDTL
SNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQKTT
EFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFLYY
KSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHR
KVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPS
IGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELV
FLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFY
IFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVI
IYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFT
VSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFGCLR"
misc_feature 1118..1276
/gene="ELTD1"
/gene_synonym="ETL"
/note="GPS; Region: Latrophilin/CL-1-like GPS domain.
Domain present in latrophilin/CL-1, sea urchin REJ and
polycystin"
/db_xref="CDD:pfam01825"
misc_feature 1292..2035
/gene="ELTD1"
/gene_synonym="ETL"
/note="7tm_2; Region: 7 transmembrane receptor (Secretin
family)"
/db_xref="CDD:pfam00002"
BASE COUNT 872 a 484 c 478 g 839 t
ORIGIN
1 gccaccactg cggccaccgc caatgaaacg cctcccgctc ctagtggttt tttccacttt
61 gttgaattgt tcctatactc aaaattgcac caagacacct tgtctcccaa atgcaaaatg
121 tgaaatacgc aatggaattg aagcctgcta ttgcaacatg ggattttcag gaaatggtgt
181 cacaatttgt gaagatgata atgaatgtgg aaatttaact cagtcctgtg gcgaaaatgc
241 taattgcact aacacagaag gaagttatta ttgtatgtgt gtacctggct tcagatccag
301 cagtaaccaa gacaggttta tcactaatga tggaaccgtc tgtatagaaa atgtgaatgc
361 aaactgccat ttagataatg tctgtatagc tgcaaatatt aataaaactt taacaaaaat
421 cagatccata aaagaacctg tggctttgct acaagaagtc tatagaaatt ctgtgacaga
481 tctttcacca acagatataa ttacatatat agaaatatta gctgaatcat cttcattact
541 aggttacaag aacaacacta tctcagccaa ggacaccctt tctaactcaa ctcttactga
601 atttgtaaaa accgtgaata attttgttca aagggataca tttgtagttt gggacaagtt
661 atctgtgaat cataggagaa cacatcttac aaaactcatg cacactgttg aacaagctac
721 tttaaggata tcccagagct tccaaaagac cacagagttt gatacaaatt caacggatat
781 agctctcaaa gttttctttt ttgattcata taacatgaaa catattcatc ctcatatgaa
841 tatggatgga gactacataa atatatttcc aaagagaaaa gctgcatatg attcaaatgg
901 caatgttgca gttgcatttt tatattataa gagtattggt cctttgcttt catcatctga
961 caacttctta ttgaaacctc aaaattatga taattctgaa gaggaggaaa gagtcatatc
1021 ttcagtaatt tcagtctcaa tgagctcaaa cccacccaca ttatatgaac ttgaaaaaat
1081 aacatttaca ttaagtcatc gaaaggtcac agataggtat aggagtctat gtgcattttg
1141 gaattactca cctgatacca tgaatggcag ctggtcttca gagggctgtg agctgacata
1201 ctcaaatgag acccacacct catgccgctg taatcacctg acacattttg caattttgat
1261 gtcctctggt ccttccattg gtattaaaga ttataatatt cttacaagga tcactcaact
1321 aggaataatt atttcactga tttgtcttgc catatgcatt tttaccttct ggttcttcag
1381 tgaaattcaa agcaccagga caacaattca caaaaatctt tgctgtagcc tatttcttgc
1441 tgaacttgtt tttcttgttg ggatcaatac aaatactaat aagctcttct gttcaatcat
1501 tgctggactg ctacactact tctttttagc tgcttttgca tggatgtgca ttgaaggcat
1561 acatctctat ctcattgttg tgggtgtcat ctacaacaag ggatttttgc acaagaattt
1621 ttatatcttt ggctatctaa gcccagccgt ggtagttgga ttttcggcag cactaggata
1681 cagatattat ggcacaacca aagtatgttg gcttagcacc gaaaacaact ttatttggag
1741 ttttatagga ccagcatgcc taatcattct tgttaatctc ttggcttttg gagtcatcat
1801 atacaaagtt tttcgtcaca ctgcagggtt gaaaccagaa gttagttgct ttgagaacat
1861 aaggtcttgt gcaagaggag ccctcgctct tctgttcctt ctcggcacca cctggatctt
1921 tggggttctc catgttgtgc acgcatcagt ggttacagct tacctcttca cagtcagcaa
1981 tgctttccag gggatgttca tttttttatt cctgtgtgtt ttatctagaa agattcaaga
2041 agaatattac agattgttca aaaatgtccc ctgttgtttt ggatgtttaa ggtaaacata
2101 gagaatggtg gataattaca actgcacaaa aataaaaatt ccaagctgtg gatgaccaat
2161 gtataaaaat gactcatcaa attatccaat tattaactac tagacaaaaa gtattttaaa
2221 tcagtttttc tgtttatgct ataggaactg tagataataa ggtaaaatta tgtatcatat
2281 agatatacta tgtttttcta tgtgaaatag ttctgtcaaa aatagtattg cagatatttg
2341 gaaagtaatt ggtttctcag gagtgatatc actgcaccca aggaaagatt ttctttctaa
2401 cacgagaagt atatgaatgt cctgaaggaa accactggct tgatatttct gtgactcgtg
2461 ttgcctttga aactagtccc ctaccacctc ggtaatgagc tccattacag aaagtggaac
2521 ataagagaat gaaggggcag aatatcaaac agtgaaaagg gaatgataag atgtattttg
2581 aatgaactgt tttttctgta gactagctga gaaattgttg acataaaata aagaattgaa
2641 gaaacacaaa aaaaaaaaaa aaaaaaaaaa aaa
//