LOCUS BC025682 1556 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens gasdermin B, mRNA (cDNA clone MGC:34771
IMAGE:5205060), complete cds.
ACCESSION BC025682
VERSION BC025682.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1556)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1556)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: g Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis, GenomeScan gene prediction.
FEATURES Location/Qualifiers
source 1..1556
/db_xref="H-InvDB:HIT000039955"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34771 IMAGE:5205060"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1556
/gene="GSDMB"
/gene_synonym="GSDML"
/gene_synonym="PP4052"
/gene_synonym="PRO2521"
/db_xref="GeneID:55876"
/db_xref="HGNC:HGNC:23690"
/db_xref="MIM:611221"
CDS 24..1259
/gene="GSDMB"
/gene_synonym="GSDML"
/gene_synonym="PP4052"
/gene_synonym="PRO2521"
/codon_start=1
/product="GSDMB protein"
/protein_id="AAH25682.1"
/db_xref="GeneID:55876"
/db_xref="HGNC:HGNC:23690"
/db_xref="MIM:611221"
/translation="MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKR
TFFGCRHYTTGLTLMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPK
EITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTE
TLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKE
TMSAGLDIHFRGKTKSFPEGKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLA
KCLGKEDIRQDLEQRVSEVLISRELHMEDSDKPLLSSLFNAAGVLVEARAKAILDFLD
ALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCAL
YVVVSILLELAEGPTSVSS"
BASE COUNT 484 a 336 c 381 g 355 t
ORIGIN
1 gtttctgagt tggtccaggc gcaatgttca gcgtatttga ggaaatcaca agaattgtag
61 ttaaggagat ggatgctgga ggggatatga ttgccgttag aagccttgtt gatgctgata
121 gattccgctg cttccatctg gtgggggaga agagaacttt ctttggatgc cggcactaca
181 caacaggcct caccctgatg gacattctgg acacagatgg ggacaagtgg ttagatgaac
241 tggattctgg gctccaaggt caaaaggctg agtttcaaat tctggataat gtagactcaa
301 cgggagagtt gatagtgaga ttacccaaag aaataacaat ttcaggcagt ttccagggct
361 tccaccatca gaaaatcaag atatcggaga accggatatc ccagcagtat ctggctaccc
421 ttgaaaacag gaagctgaag agggaactac ccttttcatt ccgatcaatt aatacgagag
481 aaaacctgta tctggtgaca gaaactctgg agacggtaaa ggaggaaacc ctgaaaagcg
541 accggcaata taaattttgg agccagatct ctcagggcca tctcagctat aaacacaagg
601 gccaaaggga agtgaccatc cccccaaatc gggtcctgag ctatcgagta aagcagcttg
661 tcttccccaa caaggagacg atgagtgctg gtttggatat tcatttcagg ggcaaaacaa
721 aatcctttcc agaaggaaag tctttgggtt cggaggattc cagaaacatg aaggagaagt
781 tggaggacat ggagagtgtc ctcaaggacc tgacagagga gaagagaaaa gatgtgctaa
841 actccctcgc taagtgcctc ggcaaggagg atattcggca ggatctagag caaagagtat
901 ctgaggtcct gatttccagg gagctacaca tggaggactc agacaagcct ctcctaagca
961 gcctttttaa tgctgctggg gtcttggtag aagcgcgtgc aaaagccatt ctggacttcc
1021 tggatgccct cctagagctg tctgaagagc agcagtttgt ggctgaggcc ctggagaagg
1081 ggacccttcc tctgttgaag gaccaggtga aatctgtcat ggagcagaac tgggatgagc
1141 tggccagcag tcctcctgac atggactatg accctgaggc acgaattctc tgtgcgctgt
1201 atgttgttgt ctctatcctg ctggagctgg ctgaggggcc tacctctgtc tcttcctaac
1261 tacaaaagcc ctttctcccc acaagcctct gggttttccc tttaccagtc tgtcctcact
1321 gccatcgcca ctaccatcct gtcaccagtg ggacctcttt aaaacaagca gccaaccatt
1381 ctttgatgta tcccattcgc tccatgttaa catccaaaac cagcctggat ttcatacatg
1441 gacttctgat taaaagtggc aggttgtgca tgttaaaaaa aaaaaaaaaa aaaaaaaaaa
1501 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//