LOCUS BC025672 2472 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens folate hydrolase (prostate-specific membrane antigen)
1, mRNA (cDNA clone MGC:34488 IMAGE:5202715), complete cds.
ACCESSION BC025672
VERSION BC025672.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2472)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2472)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (06-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 49 Row: e Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4758397.
FEATURES Location/Qualifiers
source 1..2472
/db_xref="H-InvDB:HIT000039948"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:34488 IMAGE:5202715"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2472
/gene="FOLH1"
/gene_synonym="FGCP"
/gene_synonym="GCP2"
/gene_synonym="GCPII"
/gene_synonym="mGCP"
/gene_synonym="NAALAD1"
/gene_synonym="NAALAdase"
/gene_synonym="PSM"
/gene_synonym="PSMA"
/db_xref="GeneID:2346"
/db_xref="HGNC:HGNC:3788"
/db_xref="MIM:600934"
CDS 160..2319
/gene="FOLH1"
/gene_synonym="FGCP"
/gene_synonym="GCP2"
/gene_synonym="GCPII"
/gene_synonym="mGCP"
/gene_synonym="NAALAD1"
/gene_synonym="NAALAdase"
/gene_synonym="PSM"
/gene_synonym="PSMA"
/codon_start=1
/product="folate hydrolase (prostate-specific membrane
antigen) 1"
/protein_id="AAH25672.1"
/db_xref="GeneID:2346"
/db_xref="HGNC:HGNC:3788"
/db_xref="MIM:600934"
/translation="MWNLLHETDSAVATARRPRWLCAGALVLAGGFFLLGFLFGWFIK
SSNEATNITPKHNMKAFLDELKAENIKKFLYNFTQIPHLAGTEQNFQLAKQIQSQWKE
FGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVSDIVPP
FSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQ
LAGAKGVILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANE
YAYRRGIAEAVGLPSIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFT
GNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAVEPDRYVILGGHRDSWVFGGIDPQSGA
AVVHEIVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYI
NADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSG
MPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFY
DPMFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKT
YSVSFDSLFSAVKNFTEIASKFSERLQDFDKSKHVIYAPSSHNKYAGESFPGIYDALF
DIESKVDPSKAWGEVKRQIYVAAFTVQAAAETLSEVA"
BASE COUNT 746 a 483 c 594 g 649 t
ORIGIN
1 ctggacccca ggtctggagc gaattccagc ctgcagggct gataagcgag gcattagtga
61 gattgagaga gactttaccc cgccgtggtg gttggagggc gcgcagtaga gcagcagcac
121 aggcgcgggt cccgggaggc cggctctgct cgcgccgaga tgtggaatct ccttcacgaa
181 accgactcgg ctgtggccac cgcgcgccgc ccgcgctggc tgtgcgctgg ggcgctggtg
241 ctggcgggtg gcttctttct cctcggcttc ctcttcgggt ggtttataaa atcctccaat
301 gaagctacta acattactcc aaagcataat atgaaagcat ttttggatga attgaaagct
361 gagaacatca agaagttctt atataatttt acacagatac cacatttagc aggaacagaa
421 caaaactttc agcttgcaaa gcaaattcaa tcccagtgga aagaatttgg cctggattct
481 gttgagctag cacattatga tgtcctgttg tcctacccaa ataagactca tcccaactac
541 atctcaataa ttaatgaaga tggaaatgag attttcaaca catcattatt tgaaccacct
601 cctccaggat atgaaaatgt ttcggatatt gtaccacctt tcagtgcttt ctctcctcaa
661 ggaatgccag agggcgatct agtgtatgtt aactatgcac gaactgaaga cttctttaaa
721 ttggaacggg acatgaaaat caattgctct gggaaaattg taattgccag atatgggaaa
781 gttttcagag gaaataaggt taaaaatgcc cagctggcag gggccaaagg agtcattctc
841 tactccgacc ctgctgacta ctttgctcct ggggtgaagt cctatccaga tggttggaat
901 cttcctggag gtggtgtcca gcgtggaaat atcctaaatc tgaatggtgc aggagaccct
961 ctcacaccag gttacccagc aaatgaatat gcttataggc gtggaattgc agaggctgtt
1021 ggtcttccaa gtattcctgt tcatccaatt ggatactatg atgcacagaa gctcctagaa
1081 aaaatgggtg gctcagcacc accagatagc agctggagag gaagtctcaa agtgccctac
1141 aatgttggac ctggctttac tggaaacttt tctacacaaa aagtcaagat gcacatccac
1201 tctaccaatg aagtgacaag aatttacaat gtgataggta ctctcagagg agcagtggaa
1261 ccagacagat atgtcattct gggaggtcac cgggactcat gggtgtttgg tggtattgac
1321 cctcagagtg gagcagctgt tgttcatgaa attgtgagga gctttggaac actgaaaaag
1381 gaagggtgga gacctagaag aacaattttg tttgcaagct gggatgcaga agaatttggt
1441 cttcttggtt ctactgagtg ggcagaggag aattcaagac tccttcaaga gcgtggcgtg
1501 gcttatatta atgctgactc atctatagaa ggaaactaca ctctgagagt tgattgtaca
1561 ccgctgatgt acagcttggt acacaaccta acaaaagagc tgaaaagccc tgatgaaggc
1621 tttgaaggca aatctcttta tgaaagttgg actaaaaaaa gtccttcccc agagttcagt
1681 ggcatgccca ggataagcaa attgggatct ggaaatgatt ttgaggtgtt cttccaacga
1741 cttggaattg cttcaggcag agcacggtat actaaaaatt gggaaacaaa caaattcagc
1801 ggctatccac tgtatcacag tgtctatgaa acatatgagt tggtggaaaa gttttatgat
1861 ccaatgttta aatatcacct cactgtggcc caggttcgag gagggatggt gtttgagcta
1921 gccaattcca tagtgctccc ttttgattgt cgagattatg ctgtagtttt aagaaagtat
1981 gctgacaaaa tctacagtat ttctatgaaa catccacagg aaatgaagac atacagtgta
2041 tcatttgatt cacttttttc tgcagtaaag aattttacag aaattgcttc caagttcagt
2101 gagagactcc aggactttga caaaagcaag catgtcatct atgctccaag cagccacaac
2161 aagtatgcag gggagtcatt cccaggaatt tatgatgctc tgtttgatat tgaaagcaaa
2221 gtggaccctt ccaaggcctg gggagaagtg aagagacaga tttatgttgc agccttcaca
2281 gtgcaggcag ctgcagagac tttgagtgaa gtagcctaag aggattcttt agagaatccg
2341 tattgaattt gtgtggtatg tcactcagaa agaatcgtaa tgggtatatt gataaatttt
2401 aaaattggta tatttgaaat aaagttgaat attatatata aaaaaaaaaa aaaaaaaaaa
2461 aaaaaaaaaa aa
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