LOCUS BC025025 1306 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens gamma-glutamyl hydrolase (conjugase,
folylpolygammaglutamyl hydrolase), mRNA (cDNA clone MGC:9649
IMAGE:3924620), complete cds.
ACCESSION BC025025
VERSION BC025025.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1306)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1306)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-MAR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 26 Row: f Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503986.
FEATURES Location/Qualifiers
source 1..1306
/db_xref="H-InvDB:HIT000039846"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9649 IMAGE:3924620"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1306
/gene="GGH"
/gene_synonym="GH"
/db_xref="GeneID:8836"
/db_xref="HGNC:HGNC:4248"
/db_xref="MIM:601509"
CDS 85..1041
/gene="GGH"
/gene_synonym="GH"
/codon_start=1
/product="gamma-glutamyl hydrolase (conjugase,
folylpolygammaglutamyl hydrolase)"
/protein_id="AAH25025.1"
/db_xref="GeneID:8836"
/db_xref="HGNC:HGNC:4248"
/db_xref="MIM:601509"
/translation="MASPGCLLCVLGLLLCGAASLELSRPHGDTAKKPIIGILMQKCR
NKVMKNYGRYYIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSVDL
RRSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLISGECLLTATDTVDVAM
PLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKNFTMNEKLKKFFNVLT
TNTDGKIEFISTMEGYKYPVYGVQWHPEKAPYEWKNLDGISHAPNAVKTAFYLAEFFV
NEARKNNHHFKSESEEEKALIYQFSPIYTGNISSFQQCYIFD"
BASE COUNT 396 a 245 c 286 g 379 t
ORIGIN
1 cgagtgcgct gccgcgaggt gtccctgccg cagcccccgc ccgcccgcag agcttttgaa
61 aggcggcggg aggcggcgag cgccatggcc agtccgggct gcctgctgtg cgtgctgggc
121 ctgctactct gcggggcggc gagcctcgag ctgtctagac cccacggcga caccgccaag
181 aagcccatca tcggaatatt aatgcaaaaa tgccgtaata aagtcatgaa aaactatgga
241 agatactata ttgctgcgtc ctatgtaaag tacttggagt ctgcaggtgc gagagttgta
301 ccagtaaggc tggatcttac agagaaagac tatgaaatac ttttcaaatc tattaatgga
361 atccttttcc ctggaggaag tgttgacctc agacgctcag attatgctaa agtggccaaa
421 atattttata acttgtccat acagagtttt gatgatggag actattttcc tgtgtggggc
481 acatgccttg gatttgaaga gctttcactg ctgattagtg gagagtgctt attaactgcc
541 acagatactg ttgacgtggc aatgccgctg aacttcactg gaggtcaatt gcacagcaga
601 atgttccaga attttcctac tgagttgttg ctgtcattag cagtagaacc tctgactgcc
661 aatttccata agtggagcct ctccgtgaag aattttacaa tgaatgaaaa gttaaagaag
721 tttttcaatg tcttaactac aaatacagat ggcaagattg agtttatttc aacaatggaa
781 ggatataagt atccagtata tggtgtccag tggcatccag agaaagcacc ttatgagtgg
841 aagaatttgg atggcatttc ccatgcacct aatgctgtga aaaccgcatt ttatttagca
901 gagttttttg ttaatgaagc tcggaaaaac aaccatcatt ttaaatctga atctgaagag
961 gagaaagcat tgatttatca gttcagtcca atttatactg gaaatatttc ttcatttcag
1021 caatgttaca tatttgattg aaagtcttca atttgttaac agagcaaatt tgaataattc
1081 catgattaaa ctgttagaat aacttgctac tcatggcaag attaggaagt cacagattct
1141 tttctataat gtgcctggct ctgattcttc attctgtatg tgactattta tataacatta
1201 gataattaaa tagtgagaca taaatagagt gtttttcatg gaaaagcctt cttatatctg
1261 aagattgaaa aaaataaatt tactgaaata caaaaaaaaa aaaaaa
//