LOCUS BC024179 2811 bp mRNA linear HUM 19-JUN-2008
DEFINITION Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 7, mRNA (cDNA
clone MGC:26232 IMAGE:4821164), complete cds.
ACCESSION BC024179
VERSION BC024179.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2811)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2811)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 33 Row: a Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 29826328.
FEATURES Location/Qualifiers
source 1..2811
/db_xref="H-InvDB:HIT000039750"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26232 IMAGE:4821164"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2811
/gene="PAK7"
/gene_synonym="PAK5"
/db_xref="GeneID:57144"
/db_xref="HGNC:HGNC:15916"
/db_xref="MIM:608038"
CDS 279..2438
/gene="PAK7"
/gene_synonym="PAK5"
/codon_start=1
/product="p21 protein (Cdc42/Rac)-activated kinase 7"
/protein_id="AAH24179.1"
/db_xref="GeneID:57144"
/db_xref="HGNC:HGNC:15916"
/db_xref="MIM:608038"
/translation="MFGKKKKKIEISGPSNFEHRVHTGFDAQEQKFTGLPQQWHSLLA
DTANRPKPMVDPSCITPIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRK
ESPPTPDQGASSHGPGHAEENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYY
RGSHAAKQNGHVMKMKHGEAYYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWE
YQRASSSSPLDYSFQFTPSRTAGTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQT
SPQPTMRQRSRSGSGLQEPMMPFGASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYD
RAQMVLSPPLSGSDTYPRGPAKLPQSQSKSGYSSSSHQYPSGYHKATLYHHPSLQSSS
QYISTASYLSYLSLSSSTYPPPSWGSSSDQQPSRVSHEQFRAALQLVVSPGDPREYLA
NFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVD
MYSSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLRALSYLHNQGVIH
RDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEV
DIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSVLRGFLDLMLV
REPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH"
BASE COUNT 784 a 751 c 686 g 590 t
ORIGIN
1 gtcgagagcg gagtttccca gcgtgcgccc agggagaccg ggaacatggc gctgggagcg
61 ctgtagcagc tgagaagggg ctgaggcacc gccgcttcgc tgacagccgg ccaccagaaa
121 tacactgtgg tgaaatgctt ccacctcttg ctaaaatgaa cactgaggaa aaatgaagaa
181 gactgacaag caccagcgaa aagttgcaga atagaaatag ccacactcct ctggagtctt
241 taattcatcc acagccatca tataaaggtt ttggcatcat gtttgggaag aaaaagaaaa
301 agattgaaat atctggcccg tccaactttg aacacagggt tcatactggg tttgatgcac
361 aagagcagaa gtttaccggc cttccccagc agtggcacag cctgttagca gatacggcca
421 acaggccaaa gcctatggtg gacccttcat gcatcacacc catccagctg gctcctatga
481 agacaatcgt tagaggaaac aaaccctgca aggaaacctc catcaacggc ctgctagagg
541 attttgacaa catctcggtg actcgctcca actccctaag gaaagaaagc ccacccaccc
601 cagatcaggg agcctccagc cacggtccag gccacgcgga agaaaatggc ttcatcacct
661 tctcccagta ttccagcgaa tccgatacta ctgctgacta cacgaccgaa aagtacaggg
721 agaagagtct ctatggagat gatctggatc cgtattatag aggcagccac gcagccaagc
781 aaaatgggca cgtaatgaaa atgaagcacg gggaggccta ctattctgag gtgaagcctt
841 tgaaatccga ttttgccaga ttttctgccg attatcactc acatttggac tcactgagca
901 aaccaagtga atacagtgac ctcaagtggg agtatcagag agcctcgagt agctcccctc
961 tggattattc attccaattc acaccttcta gaactgcagg gaccagcggg tgctccaagg
1021 agagcctggc gtacagtgaa agtgaatggg gacccagcct ggatgactat gacaggaggc
1081 caaagtcttc gtacctgaat cagacaagcc ctcagcccac catgcggcag aggtccaggt
1141 caggctcggg actccaggaa ccgatgatgc catttggagc aagtgcattt aaaacccatc
1201 cccaaggaca ctcctacaac tcctacacct accctcgctt gtccgagccc acaatgtgca
1261 ttccaaaggt ggattacgat cgagcacaga tggtcctcag ccctccactg tcagggtctg
1321 acacctaccc caggggccct gccaaactac ctcaaagtca aagcaaatcg ggctattcct
1381 caagcagtca ccagtacccg tctgggtacc acaaagccac cttgtaccat cacccctccc
1441 tgcagagcag ttcgcagtac atctccacgg cttcctacct gagctacctc agcctctcat
1501 ccagcaccta cccgccgccc agctggggct cctcctccga ccagcagccc tccagggtgt
1561 cccatgaaca gtttcgggcg gccctgcagc tggtggtcag cccaggagac cccagggaat
1621 acttggccaa ctttatcaaa atcggggaag gctcaaccgg catcgtatgc atcgccaccg
1681 agaaacacac agggaaacaa gttgcagtga agaaaatgga cctccggaag caacagagac
1741 gagaactgct tttcaatgag gtcgtgatca tgcgggatta ccaccatgac aatgtggttg
1801 acatgtacag cagctacctt gtcggcgatg agctctgggt ggtcatggag tttctagaag
1861 gtggtgcctt gacagacatt gtgactcaca ccagaatgaa tgaagaacag atagctactg
1921 tctgcctgtc agttctgaga gctctctcct accttcataa ccaaggagtg attcacaggg
1981 acataaaaag tgactccatc ctcctgacaa gcgatggccg gataaagttg tctgattttg
2041 gtttctgtgc tcaagtttcc aaagaggtgc cgaagaggaa atcattggtt ggcactccct
2101 actggatggc ccctgaggtg atttctaggc taccttatgg gacagaggtg gacatctggt
2161 ccctcgggat catggtgata gaaatgattg atggcgagcc cccctacttc aatgagcctc
2221 ccctccaggc gatgcggagg atccgggaca gtttacctcc aagagtgaag gacctacaca
2281 aggtttcttc agtgctccgg ggattcctag acttgatgtt ggtgagggag ccctctcaga
2341 gagcaacagc ccaggaactc ctcggacatc cattcttaaa actagcaggt ccaccgtctt
2401 gcattgtccc cctcatgaga caatacaggc atcactgagc agaggattcg tgtaggtggc
2461 aaagctagat gaggacatga gaataattca ggagaacaaa aggaaacaca gaacatgcaa
2521 aaggcctgtg cattctagac cagccaattg gtgggacagc gtgatgaccg gcagggttca
2581 acagaccagg gcatcttctt gtgtcttaaa caggcatctc tccactgaca gccggtgtgg
2641 tcacttggag cacggcttta ataagtcatt attatatttt tcagcccttc atccagcaaa
2701 tcagaaggac tcagtacaaa ctccgttatg atatatccta gccacatgca gggtaacatg
2761 taggattttc tatattgaaa gaatactttt ctggcaaaaa aaaaaaaaaa a
//