LOCUS BC023659 1045 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens proteasome (prosome, macropain) subunit, alpha type,
6, mRNA (cDNA clone MGC:29618 IMAGE:4869452), complete cds.
ACCESSION BC023659
VERSION BC023659.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1045)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1045)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: h Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 23110943.
FEATURES Location/Qualifiers
source 1..1045
/db_xref="H-InvDB:HIT000050864"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29618 IMAGE:4869452"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1045
/gene="PSMA6"
/gene_synonym="IOTA"
/gene_synonym="MGC22756"
/gene_synonym="MGC2333"
/gene_synonym="MGC23846"
/gene_synonym="p27K"
/gene_synonym="PROS27"
/db_xref="GeneID:5687"
/db_xref="HGNC:HGNC:9535"
/db_xref="MIM:602855"
CDS 79..819
/gene="PSMA6"
/gene_synonym="IOTA"
/gene_synonym="MGC22756"
/gene_synonym="MGC2333"
/gene_synonym="MGC23846"
/gene_synonym="p27K"
/gene_synonym="PROS27"
/codon_start=1
/product="proteasome (prosome, macropain) subunit, alpha
type, 6"
/protein_id="AAH23659.1"
/db_xref="GeneID:5687"
/db_xref="HGNC:HGNC:9535"
/db_xref="MIM:602855"
/translation="MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRG
KDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWK
YKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYY
CGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVG
VVTVENPKFRILTEAEIDAHLVALAERD"
BASE COUNT 351 a 195 c 237 g 262 t
ORIGIN
1 cttccgggag gtgcttgtgt gcctggtgcg ggagctacgg ggcccaggga ttgtgtttaa
61 agtagtgctt gtaccaacat gtcccgtggt tccagcgccg gttttgaccg ccacattacc
121 attttttcac ccgagggtcg gctctaccaa gtagaatatg cttttaaggc tattaaccag
181 ggtggcctta catcagtagc tgtcagaggg aaagactgtg cagtaattgt cacacagaag
241 aaagtacctg acaaattatt ggattccagc acagtgactc acttattcaa gataactgaa
301 aacattggtt gtgtgatgac cggaatgaca gctgacagca gatcccaggt acagagggca
361 cgctatgagg cagctaactg gaaatacaag tatggctatg agattcctgt ggacatgctg
421 tgtaaaagaa ttgccgatat ttctcaggtc tacacacaga atgctgaaat gaggcctctt
481 ggttgttgta tgattttaat tggtatagat gaagagcaag gccctcaggt atataagtgt
541 gatcctgcag gttactactg tgggtttaaa gccactgcag cgggagttaa acaaactgag
601 tcaaccagct tccttgaaaa aaaagtgaag aagaaatttg attggacatt tgagcagaca
661 gtggaaactg caattacatg cctgtctact gttctatcaa ttgatttcaa accttcagaa
721 atagaagttg gagtagtgac agttgaaaat cctaaattca ggattcttac agaagcagag
781 attgatgctc accttgttgc tctagcagag agagactaaa cattgtcgtt agtttaccag
841 atccgtgatg ccacttacct gtgtgtttgg taacaacaaa ccaacatcat ggaggtccct
901 ggattgaaaa aggagcctct cccactcctc ctaccaccga agtggttagg actctatata
961 aataaaaaca aggcttttgg aaaataaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1021 aaaaaaaaaa aaaaaaaaaa aaaaa
//