LOCUS BC023630 1449 bp mRNA linear HUM 19-JUN-2006
DEFINITION Homo sapiens three prime repair exonuclease 1, mRNA (cDNA clone
IMAGE:4843138), complete cds.
ACCESSION BC023630
VERSION BC023630.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1449)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1449)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 33 Row: n Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18375529
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1449
/db_xref="H-InvDB:HIT000050854"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4843138"
/tissue_type="Eye, normal, pigmented retinal epithelium"
/clone_lib="NIH_MGC_43"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1449
/gene="TREX1"
/gene_synonym="ATRIP"
/gene_synonym="DKFZp434J0310"
/gene_synonym="DRN3"
/gene_synonym="FLJ12343"
/db_xref="GeneID:11277"
/db_xref="HGNC:HGNC:12269"
/db_xref="MIM:606605"
CDS 218..1327
/gene="TREX1"
/gene_synonym="ATRIP"
/gene_synonym="DKFZp434J0310"
/gene_synonym="DRN3"
/gene_synonym="FLJ12343"
/codon_start=1
/product="three prime repair exonuclease 1"
/protein_id="AAH23630.1"
/db_xref="GeneID:11277"
/db_xref="HGNC:HGNC:12269"
/db_xref="MIM:606605"
/translation="MGPGARRQGRIVQGRPEMCFCPPPTPLPPLRILTLGTHTPTPCS
SPGSAAGTYPTMGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESP
PTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLA
NLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALE
RASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDA
HARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDP
GALSREGLLAPLGLLAILTLAVATLYGLSLATPGE"
BASE COUNT 350 a 471 c 382 g 246 t
ORIGIN
1 gccgagtcac tactgcctgc ctgcctgcct gctacggtga gtgtggcccc cacaatggga
61 tggcgcaggg caggagggcc atgggttccc ccaccccaga ctaagggggc actaggggag
121 gggccgagtc atgtgaagag ggagaccctc tcagacagtc gaatgtgctg gtcccactaa
181 ggaaaccacc tcaccctctc caacttcctg cctgaaaatg ggccctggag ctcgcagaca
241 gggcaggatt gtgcagggaa ggcctgagat gtgcttctgc ccacccccta ccccactccc
301 tccccttcgg atcttaacac tgggcactca cacacccacc ccatgctcct ctccaggctc
361 agcagcaggt acgtacccaa ccatgggctc gcaggccctg cccccggggc ccatgcagac
421 cctcatcttt ttcgacatgg aggccactgg cttgcccttc tcccagccca aggtcacgga
481 gctgtgcctg ctggctgtcc acagatgtgc cctggagagc ccccccacct ctcaggggcc
541 acctcccaca gttcctccac caccgcgtgt ggtagacaag ctctccctgt gtgtggctcc
601 ggggaaggcc tgcagccctg cagccagcga gatcacaggt ctgagcacag ctgtgctggc
661 agcgcatggg cgtcaatgtt ttgatgacaa cctggccaac ctgctcctag ccttcctgcg
721 gcgccagcca cagccctggt gcctggtggc acacaatggt gaccgctacg acttccccct
781 gctccaagca gagctggcta tgctgggcct caccagtgct ctggatggtg ccttctgtgt
841 ggatagcatc actgcgctga aggccctgga gcgagcaagc agcccctcag aacacggccc
901 aaggaagagc tacagcctag gcagcatcta cactcgcctg tatgggcagt cccctccaga
961 ctcgcacacg gctgagggtg atgtcctggc cctgctcagc atctgtcagt ggagaccaca
1021 ggccctgctg cggtgggtgg atgctcacgc caggcctttc ggcaccatca ggcccatgta
1081 tggggtcaca gcctctgcta ggaccaagcc aagaccatct gctgtcacaa ccactgcaca
1141 cctggccaca accaggaaca ctagtcccag ccttggagag agcaggggta ccaaggatct
1201 tcctccagtg aaggaccctg gagccctatc cagggagggg ctgctggccc cactgggtct
1261 gctggccatc ctgaccttgg cagtagccac actgtatgga ctatccctgg ccacacctgg
1321 ggagtaggcc aagaaggaaa atctgacgaa taaagacccc cgctgcccca taaaaaaaaa
1381 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1441 aaaaaaaaa
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