LOCUS BC023017 2139 bp mRNA linear HUM 28-JUL-2005
DEFINITION Homo sapiens natriuretic peptide receptor B/guanylate cyclase B
(atrionatriuretic peptide receptor B), mRNA (cDNA clone
IMAGE:4939622), partial cds.
ACCESSION BC023017
VERSION BC023017.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2139)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2139)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 42 Row: h Column: 10.
FEATURES Location/Qualifiers
source 1..2139
/db_xref="H-InvDB:HIT000090729"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4939622"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..2139
/gene="NPR2"
/gene_synonym="AMDM"
/gene_synonym="GUC2B"
/gene_synonym="GUCY2B"
/gene_synonym="NPRBi"
/db_xref="GeneID:4882"
/db_xref="MIM:108961"
CDS <1..1857
/gene="NPR2"
/gene_synonym="AMDM"
/gene_synonym="GUC2B"
/gene_synonym="GUCY2B"
/gene_synonym="NPRBi"
/codon_start=1
/product="NPR2 protein"
/protein_id="AAH23017.1"
/db_xref="GeneID:4882"
/db_xref="MIM:108961"
/translation="GAPPSDNPPCAFDLDDPSCDKTPLSTLAIVALGTGITFIMFGVS
SFLIFRKLMLEKELASMLWRIRWEELQFGNSERYHKGAGSRLTLSLRGSSYGSLMTAH
GKYQIFANTGHFKGNVVAIKHVNKKRIELTRQVLFELKHMRDVQFNHLTRFIGACIDP
PNICIVTEYCPRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKS
SNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPELLSGNPLPTTGMQKA
DVYSFGIILQEIALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVL
LMERCWAQDPAERPDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQ
AYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTP
MQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALAL
LDAVSSFRIRHRPHDQLRLRIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQ
ALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTYWLLGERKGPPGLL"
BASE COUNT 547 a 543 c 519 g 530 t
ORIGIN
1 ggggctcctc cctcggacaa tcccccctgt gcctttgact tggacgaccc atcctgtgat
61 aaaactccac tttcaaccct ggcaattgtg gctctgggca caggaatcac cttcatcatg
121 tttggtgttt ccagcttcct aattttccga aagctgatgc tggagaagga gctggctagc
181 atgttgtggc gtattcgctg ggaagaactg cagtttggca actcagagcg ttatcacaaa
241 ggtgcaggca gtcgcctcac actgtcgctg cggggatcca gttacggctc gctcatgaca
301 gcccatggga aataccagat ctttgccaac accggtcact tcaagggaaa tgttgtcgcc
361 atcaaacatg tgaataagaa gcgcattgag ctgacccggc aggttctgtt tgaactcaaa
421 catatgagag atgttcagtt caaccatctc actcgcttca ttggcgcctg catagaccct
481 cccaacattt gcattgtcac tgaatactgt cctcgtggga gtttacagga tattctagaa
541 aatgacagca tcaacttgga ctggatgttt cgttattcac tcattaatga ccttgttaag
601 ggcatggcct ttctccacaa cagcattatt tcatcgcatg ggagtctcaa gtcctccaac
661 tgtgtggtgg atagtcgttt tgtgctcaaa atcacagact atggcctggc cagcttccga
721 tcaactgctg aacctgatga cagccatgcc ctctatgcca agaagctgtg gactgcccca
781 gaactgctca gtgggaaccc cttgccaacc acaggcatgc agaaggctga cgtctatagc
841 tttgggatca tcctgcagga gatagcactt cgcagtggtc ctttctactt ggagggcctg
901 gacctcagcc ccaaagagat tgtccagaag gtacgaaatg gtcagcggcc atatttccgg
961 ccaagcattg accggaccca actgaatgaa gagctagttt tgctgatgga gcgatgttgg
1021 gctcaggacc cagctgagcg gccagacttt ggacagatta agggcttcat tcggcgcttt
1081 aacaaggagg gtggcaccag catattggac aacctcctgc tgcgcatgga acagtatgcc
1141 aataacttgg agaagctggt ggaggaacgc acacaggcct atctggagga aaaacgcaag
1201 gctgaagctc tgctctacca aatcctaccc cattcagtgg cagagcagtt aaaacgggga
1261 gagactgtac aggctgaggc ctttgacagt gttaccatct acttcagtga cattgttggc
1321 ttcacagcat tgtcagcaga gagcaccccc atgcaggtag tgacacttct taatgacctg
1381 tatacctgct ttgatgccat aattgacaac tttgatgtct acaaggtgga gacgattggg
1441 gatgcttaca tggtggtatc tggcctccca ggccgaaatg gtcaacgcca tgcaccagaa
1501 attgctcgta tggccctagc attactagat gcagtttctt cctttcgcat ccgccaccga
1561 ccccatgacc agctgaggct acgcataggg gtccatactg ggccagtctg tgctggggtt
1621 gttggcctga agatgccccg ttattgtctt tttggagaca cagtgaacac tgcttctcga
1681 atggagtcta atggtcaagc gctgaagatc catgtctcct ctaccaccaa ggatgcccta
1741 gatgagctag gatgcttcca gctagagctt cggggggatg tggaaatgaa gggaaaagga
1801 aagatgcgaa catactggct cttaggagag cggaaaggac ctcctggact cctgtaaacc
1861 cccattcttt ccaagtcaga tagtcttctg ctgctggtac ctgggtgggc aatggccacc
1921 atgtctgcac acaccagaaa tggacatttt catatgcaat ggaaaacagc cacaaaaaaa
1981 cctaccttat atggaagttg tagccctctg cagctcagcc ctgtacatat acctgtccct
2041 ctctggcttg gtccccttcc tccctacttt ctgtaaatat ctgtatctaa accagaatat
2101 tttggtcaaa tataaaacaa taataaaaaa aaaaaaaaa
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