LOCUS BC022242 1746 bp mRNA linear HUM 22-FEB-2007
DEFINITION Homo sapiens transforming growth factor, beta 1, mRNA (cDNA clone
MGC:22008 IMAGE:4399762), complete cds.
ACCESSION BC022242
VERSION BC022242.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1746)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1746)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-FEB-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 27 Row: e Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..1746
/db_xref="H-InvDB:HIT000039422"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22008 IMAGE:4399762"
/tissue_type="Duodenum, adenocarcinoma"
/clone_lib="NIH_MGC_88"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1746
/gene="TGFB1"
/gene_synonym="CED"
/db_xref="GeneID:7040"
/db_xref="HGNC:HGNC:11766"
/db_xref="MIM:190180"
CDS 370..1542
/gene="TGFB1"
/gene_synonym="CED"
/codon_start=1
/product="transforming growth factor, beta 1"
/protein_id="AAH22242.1"
/db_xref="GeneID:7040"
/db_xref="HGNC:HGNC:11766"
/db_xref="MIM:190180"
/translation="MPPSGLRLLLLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRK
RIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEAD
YYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRL
KLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFR
LSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRH
RRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDT
QYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS"
BASE COUNT 376 a 612 c 472 g 286 t
ORIGIN
1 cccagacctc gggcgcaccc cctgcacgcc gccttcatcc ccggcctgtc tcctgagccc
61 ccgcgcatcc tagacccttt ctcctccagg agacggatct ctctccgacc tgccacagat
121 cccctattca agaccaccca ccttctggta ccagatcgcg cccatctagg ttatttccgt
181 gggatactga gacacccccg gtccaagcct cccctccacc actgcgccct tctccctgag
241 gacctcagct ttccctcgag gccctcctac cttttgccgg gagaccccca gcccctgcag
301 gggcggggcc tccccaccac accagccctg ttcgcgctct cggcagtgcc ggggggcgcc
361 gcctccccca tgccgccctc cgggctgcgg ctgctgctgc tgctgctacc gctgctgtgg
421 ctactggtgc tgacgcctgg ccggccggcc gcgggactat ccacctgcaa gactatcgac
481 atggagctgg tgaagcggaa gcgcatcgag gccatccgcg gccagatcct gtccaagctg
541 cggctcgcca gccccccgag ccagggggag gtgccgcccg gcccgctgcc cgaggccgtg
601 ctcgccctgt acaacagcac ccgcgaccgg gtggccgggg agagtgcaga accggagccc
661 gagcctgagg ccgactacta cgccaaggag gtcacccgcg tgctaatggt ggaaacccac
721 aacgaaatct atgacaagtt caagcagagt acacacagca tatatatgtt cttcaacaca
781 tcagagctcc gagaagcggt acctgaaccc gtgttgctct cccgggcaga gctgcgtctg
841 ctgaggctca agttaaaagt ggagcagcac gtggagctgt accagaaata cagcaacaat
901 tcctggcgat acctcagcaa ccggctgctg gcacccagcg actcgccaga gtggttatct
961 tttgatgtca ccggagttgt gcggcagtgg ttgagccgtg gaggggaaat tgagggcttt
1021 cgccttagcg cccactgctc ctgtgacagc agggataaca cactgcaagt ggacatcaac
1081 gggttcacta ccggccgccg aggtgacctg gccaccattc atggcatgaa ccggcctttc
1141 ctgcttctca tggccacccc gctggagagg gcccagcatc tgcaaagctc ccggcaccgc
1201 cgagccctgg acaccaacta ttgcttcagc tccacggaga agaactgctg cgtgcggcag
1261 ctgtacattg acttccgcaa ggacctcggc tggaagtgga tccacgagcc caagggctac
1321 catgccaact tctgcctcgg gccctgcccc tacatttgga gcctggacac gcagtacagc
1381 aaggtcctgg ccctgtacaa ccagcataac ccgggcgcct cggcggcgcc gtgctgcgtg
1441 ccgcaggcgc tggagccgct gcccatcgtg tactacgtgg gccgcaagcc caaggtggag
1501 cagctgtcca acatgatcgt gcgctcctgc aagtgcagct gaggtcccgc cccgccccgc
1561 cccgccccgg caggcccggc cccaccccgc cccgcccccg ctgccttgcc catgggggct
1621 gtatttaagg acacccgtgc cccaagccca cctggggccc cattaaagat ggagagagga
1681 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1741 aaaaaa
//