LOCUS BC021983 1330 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens nucleophosmin (nucleolar phosphoprotein B23,
numatrin), mRNA (cDNA clone MGC:22736 IMAGE:4106023), complete cds.
ACCESSION BC021983
VERSION BC021983.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1330)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1330)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 32 Row: d Column: 9.
FEATURES Location/Qualifiers
source 1..1330
/db_xref="H-InvDB:HIT000039327"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22736 IMAGE:4106023"
/tissue_type="Bone marrow, acute myelogenous leukemia"
/clone_lib="NIH_MGC_55"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1330
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
CDS 99..983
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/codon_start=1
/product="nucleophosmin (nucleolar phosphoprotein B23,
numatrin)"
/protein_id="AAH21983.1"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
/translation="MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSL
RTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLEMSVQPTVSLGGFEITPPVVLRL
KCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAA
DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSS
TPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCF
RMTDQEAIQDLWQWRKSL"
BASE COUNT 450 a 223 c 317 g 340 t
ORIGIN
1 ggggctggtg tgattccgtc ctgcgcggtt gttctctgga gcagcgttct tttatctccg
61 tccgccttct ctcctaccta agtgcgtgcc gccacccgat ggaagattcg atggacatgg
121 acatgagccc cctgaggccc cagaactatc ttttcggttg tgaactaaag gccgacaaag
181 attatcactt taaggtggat aatgatgaaa atgagcacca gttatcttta agaacggtca
241 gtttaggggc tggtgcaaag gatgagttgc acattgttga agcagaggca atgaattacg
301 aaggcagtcc aattaaagta acactggcaa ctttggaaat gtctgtacag ccaacggttt
361 cccttggggg ctttgaaata acaccaccag tggtcttaag gttgaagtgt ggttcagggc
421 cagtgcatat tagtggacag cacttagtag ctgtggagga agatgcagag tcagaagatg
481 aagaggagga ggatgtgaaa ctcttaagta tatctggaaa gcggtctgcc cctggaggtg
541 gtagcaaggt tccacagaaa aaagtaaaac ttgctgctga tgaagatgat gacgatgatg
601 atgaagagga tgatgatgaa gatgatgatg atgatgattt tgatgatgag gaagctgaag
661 aaaaagcgcc agtgaagaaa tctatacgag atactccagc caaaaatgca caaaagtcaa
721 atcagaatgg aaaagactca aaaccatcat caacaccaag atcaaaagga caagaatcct
781 tcaagaaaca ggaaaaaact cctaaaacac caaaaggacc tagttctgta gaagacatta
841 aagcaaaaat gcaagcaagt atagaaaaag gtggttctct tcccaaagtg gaagccaaat
901 tcatcaatta tgtgaagaat tgcttccgga tgactgacca agaggctatt caagatctct
961 ggcagtggag gaagtctctt taagaaaata gtttaaacaa tttgttaaaa aattttccgt
1021 cttatttcat ttctgtaaca gttgatatct ggctgtcctt tttataatgc agagtgagaa
1081 ctttccctac cgtgtttgat aaatgttgtc caggttctat tgccaagaat gtgttgtcca
1141 aaatgcctgt ttagttttta aagatggaac tccacccttt gcttggtttt aagtatgtat
1201 ggaatgttat gataggacat agtagtagcg gtggtcagac atggaaatgg tggggagaca
1261 aaaatataca tgtgaaataa aactcagtat tttaataaag taaaaaaaaa aaaaaaaaaa
1321 aaaaaaaaaa
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