LOCUS BC021673 1476 bp mRNA linear HUM 02-DEC-2006
DEFINITION Homo sapiens hydroxysteroid (17-beta) dehydrogenase 11, mRNA (cDNA
clone MGC:22824 IMAGE:3827935), complete cds.
ACCESSION BC021673
VERSION BC021673.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1476)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1476)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 31 Row: d Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..1476
/db_xref="H-InvDB:HIT000039240"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22824 IMAGE:3827935"
/tissue_type="Kidney, hypernephroma"
/clone_lib="NIH_MGC_58"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1476
/gene="HSD17B11"
/gene_synonym="DHRS8"
/gene_synonym="PAN1B"
/gene_synonym="RETSDR2"
/db_xref="GeneID:51170"
/db_xref="HGNC:HGNC:22960"
CDS 105..1007
/gene="HSD17B11"
/gene_synonym="DHRS8"
/gene_synonym="PAN1B"
/gene_synonym="RETSDR2"
/codon_start=1
/product="hydroxysteroid (17-beta) dehydrogenase 11"
/protein_id="AAH21673.1"
/db_xref="GeneID:51170"
/db_xref="HGNC:HGNC:22960"
/translation="MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGA
GHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYS
SAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT
KNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCP
NFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPER
FLAVLKRKISVKFDAVIGYKMKAQ"
BASE COUNT 477 a 264 c 285 g 450 t
ORIGIN
1 ggggccctac tctttctggt gttagatcga gcaaccctct aaaagcagtt tagagtggta
61 aaaaaaaaaa aaaaacacac caaacgctcg cagccacaaa agggatgaaa tttcttctgg
121 acatcctcct gcttctcccg ttactgatcg tctgctccct agagtccttc gtgaagcttt
181 ttattcctaa gaggagaaaa tcagtcaccg gcgaaatcgt gctgattaca ggagctgggc
241 atggaattgg gagactgact gcctatgaat ttgctaaact taaaagcaag ctggttctct
301 gggatataaa taagcatgga ctggaggaaa cagctgccaa atgcaaggga ctgggtgcca
361 aggttcatac ctttgtggta gactgcagca accgagaaga tatttacagc tctgcaaaga
421 aggtgaaggc agaaattgga gatgttagta ttttagtaaa taatgctggt gtagtctata
481 catcagattt gtttgctaca caagatcctc agattgaaaa gacttttgaa gttaatgtac
541 ttgcacattt ctggactaca aaggcatttc ttcctgcaat gacgaagaat aaccatggcc
601 atattgtcac tgtggcttcg gcagctggac atgtctcggt ccccttctta ctggcttact
661 gttcaagcaa gtttgctgct gttggatttc ataaaacttt gacagatgaa ctggctgcct
721 tacaaataac tggagtcaaa acaacatgtc tgtgtcctaa tttcgtaaac actggcttca
781 tcaaaaatcc aagtacaagt ttgggaccca ctctggaacc tgaggaagtg gtaaacaggc
841 tgatgcatgg gattctgact gagcagaaga tgatttttat tccatcttct atagcttttt
901 taacaacatt ggaaaggatc cttcctgagc gtttcctggc agttttaaaa cgaaaaatca
961 gtgttaagtt tgatgcagtt attggatata aaatgaaagc gcaataagca cctagttttc
1021 tgaaaactga tttaccaggt ttaggttgat gtcatctaat agtgccagaa ttttaatgtt
1081 tgaacttctg ttttttctaa ttatccccat ttcttcaata tcatttttga ggctttggca
1141 gtcttcattt actaccactt gttctttagc caaaagctga ttacatatga tataaacaga
1201 gaaatacctt tagaggtgac tttaaggaaa atgaagaaaa agaaccaaaa tgactttatt
1261 aaaataattt ccaagattat ttgtggctca cctgaaggct ttgcaaaatt tgtaccataa
1321 ccgtttattt aacatatatt tttatttttg attgcactta aattttgtat aatttgtgtt
1381 tctttttctg ttctacataa aatcagaaac ttcaagctct ctaaataaaa tgaaggacta
1441 taaaagaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
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