LOCUS BC021622 5621 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens phosphoinositide-3-kinase, regulatory subunit 3
(gamma), mRNA (cDNA clone MGC:9142 IMAGE:3910221), complete cds.
ACCESSION BC021622
VERSION BC021622.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5621)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5621)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 15 Row: g Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40254447.
FEATURES Location/Qualifiers
source 1..5621
/db_xref="H-InvDB:HIT000039231"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9142 IMAGE:3910221"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..5621
/gene="PIK3R3"
/gene_synonym="p55"
/gene_synonym="p55-GAMMA"
/db_xref="GeneID:8503"
/db_xref="HGNC:HGNC:8981"
/db_xref="MIM:606076"
CDS 691..2076
/gene="PIK3R3"
/gene_synonym="p55"
/gene_synonym="p55-GAMMA"
/codon_start=1
/product="phosphoinositide-3-kinase, regulatory subunit 3
(gamma)"
/protein_id="AAH21622.1"
/db_xref="GeneID:8503"
/db_xref="HGNC:HGNC:8981"
/db_xref="MIM:606076"
/translation="MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKP
MTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTL
TLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPV
SRYQQDQLVKEDNIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEA
FNETIKIFEEQCHTQEQHSKEYIERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMR
LEQDLKNQALDNREIDKKMNSIKPDLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKN
EDAAENYFINEEDENLPHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYA
CSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSLNVRLAY
PVHAQMPSLCR"
BASE COUNT 1492 a 1186 c 1386 g 1557 t
ORIGIN
1 gtggctggag tccgggcaga gcttgagggc agttggtgcg gtcgggttgg ttcttacacc
61 ccggcgggag cgcccagaca agccgagctg actggacttc tccggccggc cccattcccg
121 aggctgcggc agcttcggtt ccgagaccga ccggagagga gcccgagtcc cggcctctgg
181 gggattcgct ctctgcagac cagtgggacc ccgaaacttg aacgcaatct ccagccccct
241 tttttgcctt cctttgtcac ttgcccgggt ttctcccaac gtgttctttt ttttcctctt
301 cattctccct ccttcgaagg acacaaaagt ggcttccgcg gaaagatttg gaggcggtgg
361 gagcttttct ccccggagag cgactgtgta gaaaggattt ttgggaagcc gctttttaac
421 acctctgctc tccgtccccc aagcctctgt gtaatcctct gaggagaaaa gcccatagct
481 tgaaagttcg ggggcatttt gttgtgttct gtaggagaga gggggaggac cctgttcggg
541 tagtttggcc ggactggtac tggccgttgg aaaacccgaa gtacatttcc gtgtggaact
601 tttgcagata tatattttta gatttttaaa taccagataa aaaatatatg ccttctatat
661 atctcctggc gacctgcccc tgacagcgcg atgtacaata cggtgtggag tatggaccgc
721 gatgacgcag actggaggga ggtgatgatg ccctattcga cagaactgat attttatatt
781 gaaatggatc ctccagctct tccaccaaag ccacctaagc caatgacttc agcagttcca
841 aatggaatga aggacagttc tgtttctctt caggatgcag aatggtactg gggggatatt
901 tcaagggagg aggtaaatga caaattgcgg gatatgccag atgggacctt cttggtccga
961 gatgcctcaa caaaaatgca gggagattat actttgactt tgcggaaggg aggcaataat
1021 aagttaataa agatctatca ccgggatggt aaatatggct tttctgatcc tctgacattt
1081 aattccgtgg tggagctcat taaccactat caccatgaat ctcttgctca gtacaatccc
1141 aaacttgatg tgaagctgat gtacccagtg tccagatacc aacaggatca gttggtaaaa
1201 gaagataata ttgatgcagt aggtaaaaaa ctgcaagaat accactctca gtatcaggag
1261 aagagtaaag agtatgatag gctgtatgaa gaatatacta gaacatccca ggaaatacag
1321 atgaagagga ctgcaataga agcttttaat gaaacaatta aaatatttga agagcagtgt
1381 cacacacaag aacaacatag caaagaatat attgagcgat ttcgcagaga ggggaatgaa
1441 aaggagattg aacgaattat gatgaattat gataaattga aatcacgtct gggtgagatt
1501 catgatagca aaatgcgtct agagcaggat ttgaagaatc aagctttgga caaccgagaa
1561 atagataaaa aaatgaatag catcaaacct gacctgatcc agctgcgaaa gatccgagat
1621 caacaccttg tatggctcaa tcacaaagga gtgagacaga aacgcctgaa tgtctggctg
1681 ggaattaaga atgaggatgc tgctgagaac tattttatca atgaggaaga tgaaaacctg
1741 ccccattatg atgagaaaac ctggtttgtt gaggatatca atcgagtaca agcagaggac
1801 ttgctttatg ggaaacctga tggtgcattc ttaattcgtg agagtagcaa gaaaggatgc
1861 tatgcttgct ctgtggtggc cgatggggaa gtgaagcact gtgtgatcta cagcactgct
1921 cggggctatg gctttgcaga gccctacaac ctgtacagct ctctgaagga gctagtgctc
1981 cattaccagc agacatcctt ggttcagcac aacgactccc tcaacgtcag gcttgcctac
2041 cctgttcatg cacagatgcc ctcgctttgc agataaagag gaagtgggaa gagaggtggt
2101 tctctggcat ttttttctac agtttttatt agactacgat gagggcattc tttctacata
2161 gactgcttgt tttgcacaag aagtgatttt gtgaatgtga agtggagagg ccgagcagca
2221 gccggccggg atgggggcat tagaggcctg aggttctcta ggactcagcc atgccgctgc
2281 actgacatac taagctggaa gcagatgttt tttttgaaag tctgtttcat tggggttttt
2341 gttttgttta gccagacacc ctcaacagaa tattaggctt gatggttata gcgggtgggg
2401 ttgtatttgg aagcctctga agagaccatg tctttttaaa atctaactct tgagagtgca
2461 gcaggggcat ggctctgctg ggagttgtgt tttgctttgg cagtctctct tccccccacg
2521 aagaaggctg tttaggtttt gtgatagaat gggatttgat gaaaaagaca accaaaggaa
2581 aatggggagg cttgggattt catttaaata atctaagcca agatgataaa aaaaaccttc
2641 aactgaaggt attttgtttc ttaccaacat aatttaggct tcagcatctc accagcccct
2701 ccctctgaag aagtattatg ttcagaagcc aacaaaacag tttgttgcca gaccaatgtt
2761 tgatgggaaa acgtggcact catagttgaa tgtatacttc tgtaccaaaa cttgaacata
2821 aaaagactag aatttgtgag ttttagcaaa cgctaaaatt gatcactgta actaacccct
2881 tctgtccttc ctgcctgttt ctctgagatg aggaatagca ttctttttgt ggggatggtg
2941 agctttgaat cataaaatga agttggtgct tgtatggtgt ttccttagcc taaagaatga
3001 tctgttgttt gaaacctttg taacttgttt gtatgagtaa agaaaaggtg caatgcagtg
3061 cttttagatg gcttgatata ccaaataaca atatagaaca acattattat atgtgcttcc
3121 ccaagtttaa aggccctgca gaaatagtaa acatggttta atttcccttc atttccccct
3181 cctttgctgg atggggtttt gggagctata ggttgctaag gaggggagtc agattgtggt
3241 caggtgcctc agtaaatcac agacccaggg gccctgtggt ccagggtgag agtcacacca
3301 cattacacat gtgcttccat acagtggttt ctgaagcttt tgcagggaga gaagatggct
3361 tagtgtttag actgttagta gaagccatct ggaagctttt ctctttgcct ttttttgtga
3421 tcctgccatt aaggctatgt gcagtctgcc ctcctgctcc agtggccttg attttaggcc
3481 aggaatcttc tgctccatgt ggcttaagcc ttccagctga gtgaagctag gcaaatggag
3541 tgggggcagg catctattcc tgcccccatc atgccccaca cccatcagtc aacactcatt
3601 tgacaaatag agtccagctg cctctgagcc aatcctggga ccataatagg ctcagagtga
3661 gtcagctgtt tgaacccaaa gctgtgcagt caggcaccct ggctgagcta gagaagccag
3721 tacctgcatc ttggtttata aggcttacag ctaggaaagc tctagttctg ggggtgaaag
3781 aaaaatatta gtttacctga gcacttattt ccatgacagg gtctaaaata tggaccatga
3841 tgtagacaca gatttttaat tttggaaaaa cctccagtta ctagtgacga ggatagaaag
3901 ggaagtgctt ctctttggct ttttcttggt tacactgcag tttcaggatt gggtgagaca
3961 gagacaaatg aacccccctc taaagtcatt taactaatag ccagcacatc ccttccccaa
4021 actgtcaatt gaaatcttaa ctgaaagttt tactgaataa taccaagcta attgctgttg
4081 ggcacacctg gatggctttg cacctggtgt tgaacctgct gaagcaggtg gatgctcaag
4141 attacgtgca aggaatccct cccatctggt actaaaattt cagtgtgttc tgagtgtctt
4201 ttaaaccaaa atggaaatac agatacaggg ctgtagtatt cagtaatgtg tctgctcctt
4261 gttgggcaga caccagcggt gtgcagggag agaccaagta ccatctttat ctacacttgg
4321 gctggcttgt ggagaagggc tgcttttttc agtcctacat tccttcattt tttttttcat
4381 tcttgaattc attgttttgt gggatctaag acccaggggt catttgagag gtttgacagt
4441 atcttttctg accagttgcc acatgacttg cttgaccctg agcctgtgga aatggcatag
4501 ggaccagtct actacccact gggcctggtg tgtagagggg gagagggtag caaggtgctt
4561 ctctacgccc atgacttggg agcaggtctt ggcctccttc atgagagtct agtgccatgt
4621 cctgtcccat gatctggacc ctgggactgt cttggcatct taactgcagt ttcaatgagg
4681 cagagggcaa agagagacca agatcagagg ggttcattat acccctggct agagaaccca
4741 gctactgaca tgcaagcagc ttggggctgg ctggacacag gtactaggcc cattgtttcc
4801 aggtgaagct ttcatcacag aacagtgttg tctccacctg gccttagatg gcacgccatg
4861 attcgggcct ggatagactg cctgcgtcct taccactgat ctggccaaga atgaggccct
4921 cccaacactt tcactccctc tccaagcctt gatgggacct ccacttattt aggcctcatg
4981 tgctttgaag aagctttgag agccaatgtg tcttccacgg gtctcttttt tgctacaagt
5041 aatcagcccc atgtgttctc ttaaactgag aattgcacct gggcaattcc tgttttctaa
5101 ggtggtctct gctgctattt aacaacccag agtaggcctc tgtgaggctt cagtggcctc
5161 agaaaccaga gggtccagat agggggcctg cttgggccct ctgctgccaa ctgctcaaac
5221 ctgctttagc tccagccact tgtggcaaac aacctcgttt ccttacaaat tccagcatgt
5281 gactttggtg ccgttacttg tgaaaaatct attctgttgt ctttgatgtg tccaagaaaa
5341 ttcgtgtagt ttacgtaaaa atatctgact cacaagaaag ccaactgtat gtcttgtgat
5401 gggacagttc ataatgtagt tgctagacca ctttacaaat tgttcttgtc accagatgtg
5461 ttcagacatt gctgtgcaat tgttggggag ggtaggggga aaggcgagag gagatactta
5521 ttggtctttt tgtttaatac cttccccaag aggggacagt ctggccaact tgctccagta
5581 atgcaataaa gacattgcaa taaagtaaaa aaaaaaaaaa a
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