LOCUS BC021557 2484 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens transmembrane protein 8 (five membrane-spanning
domains), mRNA (cDNA clone MGC:31822 IMAGE:4899167), complete cds.
ACCESSION BC021557
VERSION BC021557.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2484)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2484)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 40 Row: o Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 10864068.
FEATURES Location/Qualifiers
source 1..2484
/db_xref="H-InvDB:HIT000039214"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:31822 IMAGE:4899167"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_42"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2484
/gene="TMEM8"
/gene_synonym="M83"
/db_xref="GeneID:58986"
/db_xref="HGNC:HGNC:17205"
CDS 21..2336
/gene="TMEM8"
/gene_synonym="M83"
/codon_start=1
/product="transmembrane protein 8 (five membrane-spanning
domains)"
/protein_id="AAH21557.1"
/db_xref="GeneID:58986"
/db_xref="HGNC:HGNC:17205"
/translation="MGRAGTGTGGEAVAAVVAGPLLLLLLARPPPASAGYSGKSEVGL
VSEHFSQAPQRLSFYSWYGSARLFRFRVPPDAVLLRWLLQVSRESGAACTDAEITVHF
RSGAPPVINPLGTSFPDDTAVQPSFQVGVPLSTAPRSNASVNVSHPAPGDWFVAAHLP
PSSQKIELKGLAPTCAYVFQPELLVTRVVEISIMEPDVPLPQTLLSHPSYLKVFVPDY
TRELLLELRDCVSNGSLGCPVRLTVGPVTLPSNFQKVLTCTGAPWPCRLLLPSPPWDR
WLQVTAESLVGPLGTVAFSAVAALTACRPRSVTVQPLLQSSQNQSFNASSGLLSPSPD
HQDLGRSGRVDRSPFCLTNYPVTREDMDVVSVHFQPLDRVSVRVCSDTPSVMRLRLNT
GMDSGGSLTISLRANKTEMRNETVVVACVNAASPFLGFNTSLNCTTAFFQGYPLSLSA
WSRRANLIIPYPETDNWYLSLQLMCPENAEDCEQAVVHVETTLYLVPCLNDCGPYGQC
LLLRRHSYLYASCSCKAGWRGWSCTDNSTAQTVAQQRAATLLLTLSNLMFLAPIAVSV
RRFFLVEASVYAYTMFFSTFYHACDQPGEAVLCILSYDTLQYCDFLGSGAAIWVTILC
MARLKTVLKYVLFLLGTLVIAMSLQLDRRGMWNMLGPCLFAFVIMASMWAYRCGHRRQ
CYPTSWQRWAFYLLPGVSMASVGIAIYTSMMTSDNYYYTHSIWHILLAGSAALLLPPP
DQPAEPWACSQKFPCHYQICKNDREELYAVT"
BASE COUNT 416 a 862 c 726 g 480 t
ORIGIN
1 gccgggccga gcgcggagcc atgggccggg ctggcaccgg gaccgggggc gaggcggtgg
61 ccgcggtggt ggcggggccg ctgctgctgc tgctgcttgc ccggcccccg cctgcctccg
121 ccggctacag cgggaagagc gaggtggggc tggtgtccga gcacttctca caggccccgc
181 agaggctgtc cttctacagc tggtatggca gtgccaggct cttccgcttc cgcgtgcccc
241 cagatgctgt gcttctacgc tggctcctgc aggtctcccg ggagagcggc gctgcctgca
301 ccgacgcgga gatcaccgtg cacttccgtt ccggcgcccc tccggtcatc aacccgctgg
361 gcaccagctt cccggacgac accgcggtgc agccctcctt ccaggtcggg gtgccgctga
421 gcaccgcacc gagaagcaat gcctccgtca acgtttccca cccggccccc ggggactggt
481 tcgtggccgc ccacctgccc ccctcatccc agaagatcga gttgaagggc ttggctccca
541 cctgtgccta cgtcttccag cctgaactgc tggtcacgcg ggtggtcgag atttccatca
601 tggagccgga cgtgcccctt cctcagaccc tcctctccca tcccagctac ctcaaggtct
661 ttgtccccga ttacacgcgg gagcttctgc tggagctgcg ggactgcgtg tccaatggga
721 gcctgggctg ccccgtgcgt ctcaccgtgg gcccggtcac cctgcctagc aacttccaga
781 aggtgctcac ctgcaccggt gccccctggc cctgccgcct gctgctgccc tcaccgccct
841 gggaccggtg gctgcaagtg acagctgaga gcctggtggg gcccctcggg acagtggctt
901 tcagtgctgt agctgccctc acagcttgca ggccacggag cgtgaccgtc cagccccttc
961 tgcagagcag ccaaaaccag agcttcaatg cctcctctgg tctgctgtcc ccgagccccg
1021 accaccagga cctgggcagg agtggcaggg tggaccgcag ccccttctgc ctcacaaact
1081 acccagtcac gcgggaggac atggacgtgg tgtcggtgca cttccagccc ctggacaggg
1141 tctcggtgag ggtgtgttcg gacacgccct ccgtgatgcg gctgcgcctg aacaccggca
1201 tggacagcgg gggttccctc accatctccc tgcgggccaa caagacagag atgcggaacg
1261 agaccgtcgt agtggcctgc gtgaatgctg cctcgccctt ccttggcttc aatacttcgc
1321 tcaactgcac cacagccttc ttccagggct accctttgtc tctgagcgcc tggtctcgca
1381 gggccaacct catcatcccc tacccagaga cagacaactg gtacctctcc ctgcagctca
1441 tgtgccctga gaatgctgag gactgtgagc aggctgtggt ccacgtggag accaccttgt
1501 acctggtgcc ctgtttgaac gattgtggac cctatggcca gtgcctcctg ctccgcagac
1561 acagctacct gtatgccagc tgcagctgca aggcaggctg gcgtgggtgg agctgcacgg
1621 acaacagcac agcccagacg gtggcccagc agagggcggc cacactgctg ctcacgctca
1681 gcaacctcat gttcctggcc cccatcgccg tctcagtgcg gcgattcttc ctggtggagg
1741 cctccgtcta cgcctacacc atgttcttct ccacgttcta ccacgcctgc gaccagcccg
1801 gggaggcggt gctgtgcatc ctcagctacg acacgctgca gtactgcgac ttcttgggct
1861 ccggggcggc catctgggtc accatcctgt gcatggcacg gctcaagaca gtcctgaaat
1921 acgtgctgtt tcttctgggt acactggtca tcgccatgtc cttgcagctg gaccgcaggg
1981 gcatgtggaa catgctgggg ccctgcctct ttgccttcgt gatcatggcc tccatgtggg
2041 cttaccgctg cgggcaccgg cgccagtgct accccacctc gtggcagcgc tgggccttct
2101 acctcctgcc cggcgtctct atggcctctg tgggcatcgc catctacacc tccatgatga
2161 ctagcgacaa ctactactac acccacagca tctggcacat cctgctggcc gggagcgcag
2221 ccttgctgct gccgccacct gaccagcccg ccgagccctg ggcctgctcg cagaaattcc
2281 cctgccacta tcagatctgc aagaacgatc gggaggaact gtacgcagtg acgtgacact
2341 ggcctgggga cagctgctgc tctgatgacc tcttcagcca ggagctgtat cgagggggag
2401 gcgcctggtc cagccctgga cagattgatt tccagctgaa taaattggcc tagataccaa
2461 aaaaaaaaaa aaaaaaaaaa aaaa
//