LOCUS BC021219 1732 bp mRNA linear HUM 26-APR-2004
DEFINITION Homo sapiens dachshund homolog 1 (Drosophila), mRNA (cDNA clone
IMAGE:4301720), partial cds.
ACCESSION BC021219
VERSION BC021219.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1732)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1732)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC021219.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 17 Row: n Column: 15.
FEATURES Location/Qualifiers
source 1..1732
/db_xref="H-InvDB:HIT000039150"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4301720"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_46"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1732
/gene="DACH1"
/gene_synonym="DACH"
/gene_synonym="FLJ10138"
/db_xref="GeneID:1602"
/db_xref="MIM:603803"
CDS <1..1566
/gene="DACH1"
/gene_synonym="DACH"
/gene_synonym="FLJ10138"
/codon_start=1
/product="DACH1 protein"
/protein_id="AAH21219.2"
/db_xref="GeneID:1602"
/db_xref="MIM:603803"
/translation="NECKMVDLRGAKVASFTVEGCELICLPQAFDLFLKHLVGGLHTV
YTKLKRLEITPVVCNVEQVRILRGLGAIQPGVNRCKLISRKDFETLYNDCTNASSRPG
RPPKRTQSVTSPENSHIMPHSVPGLMSPGIIPPTGLTAAAAAAAAATNAAIAEAMKVK
KIKLEAMSNYHASNNQHGADSENGDMNSSVGLELPFMMMPHPLIPVSLPPASVTMAMS
QMNHLSTIANMAAAAQVQSPPSRVETSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRS
SSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPNVLPGPKEGDLAGHDMGHESKRM
HIEKDETPLSTPTARDSLDKLSLTGHGQPLPPGFPSPFLFPDGLSSIETLLTNIQGLL
KVAIDNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKK
AKRKLQEALEFETKRREQAEQTLKQAASTDSLRVLNDSLTPEIEADRSGGRTDAERTI
QDGRLYLKTTVMY"
misc_feature 1..291
/gene="DACH1"
/gene_synonym="DACH"
/gene_synonym="FLJ10138"
/note="Ski_Sno; Region: SKI/SNO/DAC family. This family
contains a presumed domain that is about 100 amino acids
long. All members of this family contain a conserved CLPQ
motif. The c-ski proto-oncogene has been shown to
influence proliferation, morphological transformation and
myogenic differentiation. Sno, a Ski proto-oncogene
homologue, is expressed in two isoforms and plays a role
in the response to proliferation stimuli. Dachshund also
contains this domain. It is involved in various aspects of
development"
/db_xref="CDD:pfam02437"
BASE COUNT 524 a 412 c 419 g 377 t
ORIGIN
1 aatgagtgca aaatggtgga tctgaggggg gccaaagtgg cttccttcac ggtggagggc
61 tgcgagctga tctgcctgcc ccaggctttc gacctgttcc tgaagcactt ggtggggggc
121 ttgcatacgg tctacaccaa gctgaagcgg ctggagatca cgccggtggt gtgcaatgtg
181 gaacaagttc gcatcctgag gggactgggc gccatccagc caggagtgaa ccgctgcaaa
241 ctcatctcca ggaaggactt cgagaccctc tacaatgact gcaccaacgc aagttctaga
301 cctggaaggc ctcctaagag gactcaaagt gtcacctccc cagagaactc tcacatcatg
361 ccgcattctg tccctggtct catgtctcct gggataattc caccaacagg tctgacagca
421 gccgctgcag cagctgctgc tgctaccaat gcagctattg ctgaagcaat gaaggtgaaa
481 aaaatcaaat tagaagccat gagcaactat catgccagta ataaccaaca tggagcagac
541 tctgaaaacg gggacatgaa ttcaagtgtc ggactggaac ttccttttat gatgatgccc
601 caccctctaa ttcctgtcag cctacctcca gcatctgtca ccatggcaat gagccagatg
661 aaccacctca gcaccattgc aaatatggca gcagcagcac aagttcagag tcccccatcc
721 agagttgaga catcagttat taaggagcgt gttcctgata gcccctcacc tgccccctct
781 ctggaggagg ggagaaggcc tggcagtcac ccatcatcac atcgcagcag cagcgtgtcc
841 agctcccctg ctcggactga gagctcttct gacagaatcc cggtccatca gaatgggttg
901 tccatgaacc agatgctgat gggcttatca ccaaatgtac ttcctgggcc caaagaggga
961 gatttggccg gtcatgacat gggacatgag tcaaaaagga tgcatattga aaaagatgag
1021 accccgcttt ctacaccaac cgcaagagac agccttgaca aactctctct aactgggcat
1081 ggacaaccac tgcctccagg ttttccatct ccttttctgt ttcctgatgg actgtcttcc
1141 atcgagactc ttctgactaa catacagggg ctgttgaaag ttgccataga taatgccaga
1201 gctcaagaga aacaggtcca actggaaaaa actgagctga agatggattt tttaagggaa
1261 agagaactaa gggaaacact tgagaagcag ttggctatgg aacaaaagaa tagagccata
1321 gttcaaaaga ggctaaagaa ggagaagaag gcaaagagaa aattgcagga agcacttgag
1381 tttgagacga aacggcgtga acaagcagaa cagacgctaa aacaggcagc ttcaacagat
1441 agtctcaggg tcttaaatga ctctctgacc ccagagatag aggctgaccg cagtggcggc
1501 agaacagatg ctgaaaggac aatacaagat ggaagactgt atttgaaaac tactgtcatg
1561 tactgaatct ttcctgttga agaaatccat gttatagaaa agaactttgc agtcagacat
1621 tcgtcatggg aaagttcaga aaaaaataaa gtccttttaa gggaacttcc tgaattttgt
1681 gtattaatgt tctttaaaag tttaagtatt ctacaaaaaa aaaaaaaaaa aa
//