LOCUS BC021197 2131 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens chromosome 21 open reading frame 29, mRNA (cDNA clone
IMAGE:3940847), partial cds.
ACCESSION BC021197
VERSION BC021197.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2131)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2131)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (14-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC021197.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 15 Row: k Column: 5.
FEATURES Location/Qualifiers
source 1..2131
/db_xref="H-InvDB:HIT000039134"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3940847"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2131
/gene="C21orf29"
/gene_synonym="MGC11251"
/gene_synonym="TSPEAR"
/db_xref="GeneID:54084"
CDS <1..1752
/gene="C21orf29"
/gene_synonym="MGC11251"
/gene_synonym="TSPEAR"
/codon_start=1
/product="C21orf29 protein"
/protein_id="AAH21197.2"
/db_xref="GeneID:54084"
/translation="RNQEGRRGCCSSDLRPLDILAEVVPSDGATSGIRIVQVHGARGL
QLSVAAPRTMSFPASRIFSQCDLFPEEFSIVVTLRVPNLPPKRNEYLLTVVAEESDLL
LLGLRLSPAQLHFLFLREDTAGAWQTRVSFRSPALVDGRWHTLVLAVSAGVFSLTTDC
GLPVDIMADVPFPATLSVKGARFFVGSRRRAKGLFMGLVRQLVLLPGSDATPRLCPSR
NAPLAVLSIPRVLQALTGKPEDNEVLKYPYETNIRVTLGPQPPCTEVEDAQFWFDASR
KGLYLCVGNEWVSVLAAKERLDYVEEHQNLSTNSETLGIEVFRIPQVGLFVATANRKA
TSAVYKWTEEKFVSYQNIPTHQAQAWRHFTIGKKIFLAVANFEPDEKGQEFSVIYKWS
HRKLKFTPYQSIATHSARDWEAFEVDGEHFLAVANHREGDNHNIDSVIYKWNPATRLF
EANQTIATSGAYDWEFFSVGPYSFLVVANTFNGTSTKVHSHLYIRLLGSFQLFQSFPT
FGAADWEVFQIGERIFLAVANSHSYDVEMQVQNDSYVINSVIYELNVTAQAFVKFQDI
LTCSGGRRGLHARRAEG"
misc_feature 202..621
/gene="C21orf29"
/gene_synonym="MGC11251"
/gene_synonym="TSPEAR"
/note="TSPN; Region: Thrombospondin N-terminal -like
domains"
/db_xref="CDD:smart00210"
misc_feature 1006..1281
/gene="C21orf29"
/gene_synonym="MGC11251"
/gene_synonym="TSPEAR"
/note="EPTP; Region: EPTP domain. Mutations in the
LGI/Epitempin gene can result in a special form of
epilepsy, autosomal dominant lateral temporal epilepsy.
The Epitempin protein contains a large repeat in its C
terminal section. This presumed domain has no known
function, but might form an Ig like fold"
/db_xref="CDD:pfam03736"
BASE COUNT 469 a 639 c 608 g 415 t
ORIGIN
1 aggaaccagg aaggcagacg cggctgctgt agctcagacc tgcgccccct ggacatcctg
61 gcggaagtgg tcccttctga tggcgccaca agcgggatca ggatagttca ggttcacggt
121 gcacggggac tccagctctc agtagccgcc ccccgcacca tgagcttccc agcatccagg
181 attttctccc agtgtgacct cttccctgaa gaattttcca tcgtcgtaac tttgagagtt
241 cccaatcttc cacccaagag gaacgagtac ctgctgacgg tggtggcaga ggagagcgac
301 ctgctgctgc tcggcctgcg gttgtcacct gcccagctgc acttcctgtt ccttcgcgag
361 gacacggccg gcgcctggca gacccgagtg tccttccgca gcccggccct ggtggatggc
421 cgctggcaca cactggtcct ggctgtgtcc gcaggcgtct tctccctcac cacggactgc
481 ggcctcccgg tggacataat ggccgatgtg cccttcccag ccaccctgtc agtgaaagga
541 gctcgattct tcgtcggcag ccggaggaga gccaaaggcc tgttcatggg actggtgagg
601 caactggtcc tgctgccggg ctcagacgcc accccaaggc tgtgtcccag caggaacgcc
661 ccgctggcgg tgctgtccat cccacgggtc ctgcaggctc tcacggggaa gccagaagat
721 aacgaggtgc taaaatatcc ctatgaaacc aacattcgag tgacgctggg accccagcca
781 ccgtgtaccg aggtggaaga cgcccagttc tggtttgatg ccagccggaa gggcctgtat
841 ctgtgtgttg gcaacgagtg ggtctccgtg ttagcagcca aagaaagact ggactacgtg
901 gaggagcatc agaacttgtc caccaactca gagaccctgg gcattgaggt gttccgcatc
961 cctcaggtgg ggctctttgt ggccacagcc aatcgcaaag ccacatccgc cgtctacaag
1021 tggaccgaag agaagttcgt ctcatatcag aacatcccca cgcaccaagc acaggcctgg
1081 aggcatttca ccatcgggaa aaagatcttc ctggcagtgg ctaattttga accagatgag
1141 aagggtcagg agttctctgt catttacaaa tggagccaca gaaagctgaa gtttacccca
1201 tatcagagca ttgccacaca cagcgcccga gactgggagg ccttcgaggt ggatggggag
1261 cacttcctgg cggtggccaa ccaccgggaa ggcgacaacc acaacatcga cagtgtcatc
1321 tacaagtgga acccggcaac ccggctcttc gaggccaacc agaccatcgc cacctccggc
1381 gcctacgact gggagttctt cagtgtgggg ccctactcgt tcctggtggt ggccaacacc
1441 ttcaacggca cctccaccaa ggtgcactcg cacctctaca tccgactcct gggctccttc
1501 cagctcttcc agtccttccc gacgttcggt gctgcagact gggaggtctt ccagatcggg
1561 gagaggatct tcctcgctgt ggcaaacagt cacagctacg atgtggagat gcaagtccag
1621 aatgattcct atgtcatcaa ctccgtcatc tacgagctga acgtgaccgc gcaggccttt
1681 gtcaagttcc aggacattct cacctgcagt ggaggcagga gggggcttca tgcccgtcgt
1741 gcggagggat agccgaggcc ccagagggac aggtgcgagg tgcaggcttc gagtgcccgc
1801 tgcctgccag tgccagctgc caccagacat gattacttcc ttcccccgat gttgcatcct
1861 ccccgacaac aaacaccagg acacggagac tggcctgttg agacagatgt gagatccagg
1921 gaacatggag ggtgggtctg tatgtacgag aaagtgatgg ttccagaccg acacgctccg
1981 tggagccaca ggaggttgcg tgggcaccac attttggaca gtgggcactg agaatccaca
2041 accatcctga ccagtgtggg gcgtcctctg gggtggaatt ccggtctgtg aataaacctg
2101 caatcgaatc cgtaaaaaaa aaaaaaaaaa a
//