LOCUS BC021134 3643 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens centrobin, centrosomal BRCA2 interacting protein, mRNA
(cDNA clone MGC:32051 IMAGE:4859539), complete cds.
ACCESSION BC021134
VERSION BC021134.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3643)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3643)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 40 Row: j Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 29789292.
FEATURES Location/Qualifiers
source 1..3643
/db_xref="H-InvDB:HIT000039105"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:32051 IMAGE:4859539"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3643
/gene="CNTROB"
/gene_synonym="LIP8"
/gene_synonym="PP1221"
/db_xref="GeneID:116840"
/db_xref="HGNC:HGNC:29616"
CDS 826..3537
/gene="CNTROB"
/gene_synonym="LIP8"
/gene_synonym="PP1221"
/codon_start=1
/product="centrobin, centrosomal BRCA2 interacting
protein"
/protein_id="AAH21134.1"
/db_xref="GeneID:116840"
/db_xref="HGNC:HGNC:29616"
/translation="MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRL
SRQAEATARAQLYLPSTSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESV
RGQLQTMLQTSRDTAYRDPLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQ
ALEELFPRYTSLRPGPPLNPPDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQL
AVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQE
TVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEER
DAARAGQLSEHRELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQ
REAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESE
LAVQLEQRVTERLAQAQESSLRQAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMA
EREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQAHWDEANQ
LLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVWTMPPMAVALKPVLQQSREARDELP
GAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDLTSSTAGAFSALGAFHPDHRAER
PFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETVPQNNENPSVDLLPPKSGPLT
VPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSHSQGSGPSSGSPERGGDGL
TFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTDGRGDNVPRRNTDSRLG
EIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRGGVWR"
BASE COUNT 840 a 1001 c 1106 g 696 t
ORIGIN
1 gcgtgagagg gggatctcag gggaggaggt caatcgcttg ccccccactt tggcaaattg
61 gggactgagg actggaaggg tggagagtag gcggaaccag gtggtcgtcg gggcagagga
121 tctcgggcta ggcttgaggg cggcgtgctt cttagggacg acttagggcg tgactgaggg
181 ttcacaaggt ttcttttggg gtggtcggga gggagagatt ctagggaaca aggaagctcg
241 ctatggcttt cttgccagga ggggtcgaag ggaaagtaca agggagctga ccctgggtag
301 aacgggtgaa gggatggggg agcgtgaggt tccgccctct cttgagactg gaaccaattg
361 agggactagt agggcagggg gacagaaatt gggctcctag tggatttggg tccgtttccg
421 ttgggacgtt ttgggtgtga gaacttaaga gctcagttga ccggggatag cctgtgccgg
481 agttgatctg cagcttccag cactcgtagt cgggaagagg agcttcagca gcgctgttgt
541 cccacagtag gtcttctgtc cgcacccgct ctgcgctgca ccctcttaac gctgttccca
601 ggagctgggg aaagggatgc ttttgcccac tcccatggcc cctggaactg gtggaaacct
661 ttcctctaac cagaaagcct cgatatcctt aattcaccaa ggatccttgg cgtggagtct
721 tcctcccttc tcccaagtct ttctccgtga acttttcctc ctggactttg ctaaagcaga
781 acctcccagc tctttgctgt ctccggttgt ctcttccctg tattcatggc aacatcagct
841 gacagcccca gttcacccct cggggcggag gatctcctga gtgattcatc agaaccccct
901 gggctcaacc aagtgtcgtc tgaagtgacc tcccagctct atgcttcttt gcgcctcagc
961 cggcaggcgg aggccacggc ccgagcccag ctgtatttac cctccacctc cccgcctcat
1021 gaagggttag acggcttcgc ccaagaattg agtcgaagct tgtcagtcgg attggaaaag
1081 aacttgaaga aaaaggatgg ttctaagcat atctttgaga tggaaagtgt tcggggtcag
1141 ctccagacca tgctccaaac ctcacgtgat acagcctatc gggatcctct cattcctggc
1201 gctggctcag agagacggga agaggactcc tttgacagtg atagcacagc caccttgctc
1261 aacacccggc ccctgcaaga cttgtctcca tctagctcag cccaagccct ggaggagctg
1321 tttccccgct acaccagcct tcggccaggg cctccactca atcccccaga ttttcagggg
1381 ctgagagatg cattggattc agagcatacc cgccgcaagc attgtgagcg ccatattcag
1441 agcctgcaga cccgagtgtt agagctacag caacaattag ccgtggctgt ggctgccgac
1501 cgcaagaaag ataccatgat tgaacaactg gacaagaccc tggcccgtgt ggtggagggc
1561 tggaaccggc atgaggctga gcggacagag gttctcaggg gacttcaaga ggaacaccag
1621 gcagcagagc tcaccagaag caagcagcag gagacagtaa cccgcctgga acaaagcctt
1681 tctgaggcca tggaggccct gaatcgtgag caggaaagtg ccagactgca gcaacgggaa
1741 agagagacac tggaggagga aaggcaagct ctgactctga ggttggaggc agaacagcag
1801 cggtgctgtg tcctgcagga agagcgggat gcagctcggg ctgggcaact gagtgagcat
1861 cgagagttgg agactcttcg ggctgcccta gaagaagaac ggcagacctg ggcccagcaa
1921 gagcaccagc ttaaggaaca ctaccaggcg ctgcaggagg agagccaggc tcagctggaa
1981 agggagaagg agaagagcca gagggaagcc caggccgcct gggagaccca gcaccagttg
2041 gcattggtgc agtctgaggt gcggcggctg gaaggagagc tggatacagc tcggagagag
2101 agagatgccc tgcagctgga aatgagcttg gtgcaggccc ggtatgaaag ccagcggatc
2161 cagctggagt cggagctggc tgtgcagctg gagcagcggg tgacagagcg gctggcgcag
2221 gctcaggaga gcagcctacg gcaagcagcc tccctcaggg aacatcacag gaagcagctg
2281 caggacctga gtggacagca ccagcaggag ctggccagtc agctagctca gttcaaggtg
2341 gaaatggcag aacgagagga acggcaacag caggtggctg aggactacga gctcagactg
2401 gcccgggagc aagcgcgagt gtgcgaactg cagagtggga accagcagct ggaggagcag
2461 cgggtggagc tggtggaaag actgcaggcc atgctgcagg cccactggga tgaggccaac
2521 cagctgctca gcaccactct cccgccgccc aaccctccag ctcctcctgc tggaccctcc
2581 agccccgggc ctcaggagcc cgagaaggag gagaggaggg tctggactat gcctcccatg
2641 gccgtggccc tgaagcctgt attgcagcag agccgggaag caagggacga gctacctgga
2701 gcgcctcctg ttctttgcag ttcctcctca gatcttagcc tcctgttggg cccctctttt
2761 cagagccagc attctttcca gcccctggag cccaaaccag acctcacttc atccacagct
2821 ggggccttct ctgcacttgg ggccttccat cccgatcata gggcagaaag gccattccct
2881 gaggaagatc ctggacctga cggggagggc ctcctaaagc aagggctgcc gcctgctcag
2941 ctggagggcc tcaagaattt tttgcaccag ttgctggaga cagtgcccca gaacaatgag
3001 aacccttctg tcgacctgtt gccccctaag tctggtcctc tgactgtccc atcttgggag
3061 gaagcccctc aagtgccacg tattccaccg cctgtccaca aaaccaaagt tcccttagcc
3121 atggcatcca gtcttttccg ggtccctgag cctccctcct cccattcaca aggcagtggt
3181 cccagcagtg gttccccaga gagaggtgga gatgggctta cattcccaag gcagctgatg
3241 gaggtgtctc aactgttgcg actctaccag gctcggggct ggggggctct gcctgctgag
3301 gatctcctgc tctacctgaa gaggctggaa cacagcggga ctgatggccg aggggataat
3361 gtccccagaa ggaacacaga ctcccgcttg ggtgagatcc cccggaaaga gattccctcc
3421 caggctgtcc ctcgccgcct tgctacagcc cccaagactg aaaaacctcc cgcacggaag
3481 aaaagtgggc accctgcccc gagtagcatg aggagccggg ggggagtctg gagatgagcc
3541 cccctaccct ctctcctctt tgttctctca ttgttgttat tttaataaat gctcattagt
3601 ctgtaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//