LOCUS BC020994 2872 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens promyelocytic leukemia, mRNA (cDNA clone MGC:2415
IMAGE:2958462), complete cds.
ACCESSION BC020994
VERSION BC020994.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2872)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2872)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC020994.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 2 Row: i Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 67089152.
FEATURES Location/Qualifiers
source 1..2872
/db_xref="H-InvDB:HIT000039072"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2415 IMAGE:2958462"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2872
/gene="PML"
/gene_synonym="MYL"
/gene_synonym="PP8675"
/gene_synonym="RNF71"
/gene_synonym="TRIM19"
/db_xref="GeneID:5371"
/db_xref="HGNC:HGNC:9113"
/db_xref="MIM:102578"
CDS 62..2407
/gene="PML"
/gene_synonym="MYL"
/gene_synonym="PP8675"
/gene_synonym="RNF71"
/gene_synonym="TRIM19"
/codon_start=1
/product="promyelocytic leukemia"
/protein_id="AAH20994.1"
/db_xref="GeneID:5371"
/db_xref="HGNC:HGNC:9113"
/db_xref="MIM:102578"
/translation="MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTER
APASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTP
ALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLK
HEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALL
DSSHSDLKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETE
ELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQ
RMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQ
GKDAAVSKKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKE
ARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERV
VVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPC
GTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAIRLRHAL
RLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGISPPHRIRGAVR
SRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGEGRAQTLGAVVPPGDSVR
GSMEASQVQVPLEASPITFPPPCAPERPPISPVPGARQAGL"
BASE COUNT 586 a 1005 c 793 g 488 t
ORIGIN
1 cttcagcttc tcttcacgca ctccaagatc taaaccgaga atcgaaacta agctggggtc
61 catggagcct gcacccgccc gatctccgag gccccagcag gaccccgccc ggccccagga
121 gcccaccatg cctccccccg agaccccctc tgaaggccgc cagcccagcc ccagccccag
181 ccctacagag cgagcccccg cttcggagga ggagttccag tttctgcgct gccagcaatg
241 ccaggcggaa gccaagtgcc cgaagctgct gccttgtctg cacacgctgt gctcaggatg
301 cctggaggcg tcgggcatgc agtgccccat ctgccaggcg ccctggcccc taggtgcaga
361 cacacccgcc ctggataacg tctttttcga gagtctgcag cggcgcctgt cggtgtaccg
421 gcagattgtg gatgcgcagg ctgtgtgcac ccgctgcaaa gagtcggccg acttctggtg
481 ctttgagtgc gagcagctcc tctgcgccaa gtgcttcgag gcacaccagt ggttcctcaa
541 gcacgaggcc cggcccctag cagagctgcg caaccagtcg gtgcgtgagt tcctggacgg
601 cacccgcaag accaacaaca tcttctgctc caaccccaac caccgcaccc ctacgctgac
661 cagcatctac tgccgaggat gttccaagcc gctgtgctgc tcgtgcgcgc tccttgacag
721 cagccacagt gatctcaagt gcgacatcag cgcagagatc cagcagcgac aggaggagct
781 ggacgccatg acgcaggcgc tgcaggagca ggatagtgcc tttggcgcgg ttcacgcgca
841 gatgcacgcg gctgtcggcc agctgggccg cgcgcgtgcc gagaccgagg agctgatccg
901 cgagcgcgtg cgccaggtgg tagctcacgt gcgggctcag gagcgcgagc tgctggaggc
961 tgtggacgcg cggtaccagc gcgactacga ggagatggcc agtcggctgg gccgcctgga
1021 tgctgtgctg cagcgcatcc gcacgggcag cgcgctggtg cagaggatga agtgctacgc
1081 ctcggaccag gaggtgctgg acatgcacgg tttcctgcgc caggcgctct gccgcctgcg
1141 ccaggaggag ccccagagcc tgcaagctgc cgtgcgcacc gatggcttcg acgagttcaa
1201 ggtgcgcctg caggacctca gctcttgcat cacccagggg aaagatgcag ctgtatccaa
1261 gaaagccagc ccagaggctg ccagcactcc cagggaccct attgacgttg acctggatgt
1321 ctccaataca acgacagccc agaagaggaa gtgcagccag acccagtgcc ccaggaaggt
1381 catcaagatg gagtctgagg aggggaagga ggcaaggttg gctcggagct ccccggagca
1441 gcccaggccc agcacctcca aggcagtctc accaccccac ctggatggac cgcctagccc
1501 caggagcccc gtcataggaa gtgaggtctt cctgcccaac agcaaccacg tggccagtgg
1561 cgccggggag gcagaggaac gcgttgtggt gatcagcagc tcggaagact cagatgccga
1621 aaactcgtgc atggagccca tggagaccgc cgagccacag tcctcgccag cccactcctc
1681 gccagcccac tcctcgccag cccactcctc gccagtccag tctctgctga gagcacaagg
1741 agcctccagc ctgccctgtg gcacatacca ccccccagct tggcctcccc accagcccgc
1801 tgagcaggct gccacccccg atgctgagcc tcacagcgag cctcctgatc accaggagcg
1861 ccctgccgtc caccgtggga tccgctacct gttgtacaga gcacagagag ccatccgcct
1921 tcgccatgcc ctccgcttgc accctcaatt gcatcgggcc cctattcgga cttggtctcc
1981 ccatgtggtc caagccagca ctcctgccat cacagggccc ctcaaccatc ctgccaatgc
2041 ccaggaacat cctgcccagc tgcaaagggg catcagccca ccccaccgga tacgaggggc
2101 tgtgcgatcc cgcagccgct ccctccgggg ctcctcccat ttatcccagt ggctcaacaa
2161 cttttttgcc ctccccttct cctccatggc ttcccagctt gacatgtctt ccgtggtggg
2221 ggcaggggaa ggcagagccc agactcttgg agcagttgtt ccccctgggg actctgtcag
2281 aggctccatg gaggcctctc aagtccaagt gcctctggaa gcctctccaa ttacattccc
2341 accaccctgt gccccagaaa ggccccccat cagcccagtc ccaggcgccc gtcaagcagg
2401 cctctgagag tgctaccctt ctcttgtaac cttgcagcca acacccctgc ccggcccctg
2461 agctgcctcc tccagcccat gctcttacag gccctgcaca gagtagcact cattaattct
2521 tggttaagga atgaatcaac gaatgaatgg ctatgcatgg acctctgggc agggagacct
2581 gggtcttctc tggctgagag gggaaggcta aggcatggct gagattcaag ccaccattcc
2641 aggcctcttt gcccaagaaa gaaacttctg tcacccttgc actctcctgt gttctgagtc
2701 cctggccaat agcacagcct tccatgcccc gacccccacc ccaagcctct ccactaggcc
2761 tctgccagga tctaagccca tgagcacagg gactggctat cccaagacct ggcagatgtg
2821 gctgctcaat aaacacttgt tgaaccatca aaaaaaaaaa aaaaaaaaaa aa
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