LOCUS BC020057 3656 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens integrin, beta 1 (fibronectin receptor, beta
polypeptide, antigen CD29 includes MDF2, MSK12), mRNA (cDNA clone
MGC:17220 IMAGE:3924411), complete cds.
ACCESSION BC020057
VERSION BC020057.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3656)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3656)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 26 Row: e Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 19743820.
FEATURES Location/Qualifiers
source 1..3656
/db_xref="H-InvDB:HIT000038726"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17220 IMAGE:3924411"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3656
/gene="ITGB1"
/gene_synonym="CD29"
/gene_synonym="GPIIA"
/gene_synonym="VLAB"
/db_xref="GeneID:3688"
/db_xref="HGNC:HGNC:6153"
/db_xref="MIM:135630"
CDS 66..2462
/gene="ITGB1"
/gene_synonym="CD29"
/gene_synonym="GPIIA"
/gene_synonym="VLAB"
/codon_start=1
/product="integrin, beta 1 (fibronectin receptor, beta
polypeptide, antigen CD29 includes MDF2, MSK12)"
/protein_id="AAH20057.1"
/db_xref="GeneID:3688"
/db_xref="HGNC:HGNC:6153"
/db_xref="MIM:135630"
/translation="MNLQPIFWIGLISSVCCVFAQTDENRCLKANAKSCGECIQAGPN
CGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPRGSKDIKKNKNVTNRSKGT
AEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLE
NVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFS
YKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVF
STDAGFHFAGDGKLGGIVLPNDGQCHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTI
FAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENGKLSEG
VTISYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPKKDSDSFKIRPLGF
TEEVEVILQYICECECQSEGIPESPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVN
SEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGL
ICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGICECGVCKCTDPK
FQGQTCEMCQTCLGVCAEHKECVQCRAFNKGEKKDTCTQECSYFNITKVESRDKLPQP
VQPDPVSHCKEKDVDDCWFYFTYSVNGNNEVMVHVVENPECPTGPDIIPIVAGVVAGI
VLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK
"
BASE COUNT 1136 a 612 c 820 g 1088 t
ORIGIN
1 agcgggagtc gcggaacagc aggcccgagc ccaccgcgcc gggccccgga cgccgcgcgg
61 aaaagatgaa tttacaacca attttctgga ttggactgat cagttcagtt tgctgtgtgt
121 ttgctcaaac agatgaaaat agatgtttaa aagcaaatgc caaatcatgt ggagaatgta
181 tacaagcagg gccaaattgt gggtggtgca caaattcaac atttttacag gaaggaatgc
241 ctacttctgc acgatgtgat gatttagaag ccttaaaaaa gaagggttgc cctccagatg
301 acatagaaaa tcccagaggc tccaaagata taaagaaaaa taaaaatgta accaaccgta
361 gcaaaggaac agcagagaag ctcaagccag aggatattac tcagatccaa ccacagcagt
421 tggttttgcg attaagatca ggggagccac agacatttac attaaaattc aagagagctg
481 aagactatcc cattgacctc tactacctta tggacctgtc ttactcaatg aaagacgatt
541 tggagaatgt aaaaagtctt ggaacagatc tgatgaatga aatgaggagg attacttcgg
601 acttcagaat tggatttggc tcatttgtgg aaaagactgt gatgccttac attagcacaa
661 caccagctaa gctcaggaac ccttgcacaa gtgaacagaa ctgcaccagc ccatttagct
721 acaaaaatgt gctcagtctt actaataaag gagaagtatt taatgaactt gttggaaaac
781 agcgcatatc tggaaatttg gattctccag aaggtggttt cgatgccatc atgcaagttg
841 cagtttgtgg atcactgatt ggctggagga atgttacacg gctgctggtg ttttccacag
901 atgccgggtt tcactttgct ggagatggga aacttggtgg cattgtttta ccaaatgatg
961 gacaatgtca cctggaaaat aatatgtaca caatgagcca ttattatgat tatccttcta
1021 ttgctcacct tgtccagaaa ctgagtgaaa ataatattca gacaattttt gcagttactg
1081 aagaatttca gcctgtttac aaggagctga aaaacttgat ccctaagtca gcagtaggaa
1141 cattatctgc aaattctagc aatgtaattc agttgatcat tgatgcatac aattcccttt
1201 cctcagaagt cattttggaa aacggcaaat tgtcagaagg agtaacaata agttacaaat
1261 cttactgcaa gaacggggtg aatggaacag gggaaaatgg aagaaaatgt tccaatattt
1321 ccattggaga tgaggttcaa tttgaaatta gcataacttc aaataagtgt ccaaaaaagg
1381 attctgacag ctttaaaatt aggcctctgg gctttacgga ggaagtagag gttattcttc
1441 agtacatctg tgaatgtgaa tgccaaagcg aaggcatccc tgaaagtccc aagtgtcatg
1501 aaggaaatgg gacatttgag tgtggcgcgt gcaggtgcaa tgaagggcgt gttggtagac
1561 attgtgaatg cagcacagat gaagttaaca gtgaagacat ggatgcttac tgcaggaaag
1621 aaaacagttc agaaatctgc agtaacaatg gagagtgcgt ctgcggacag tgtgtttgta
1681 ggaagaggga taatacaaat gaaatttatt ctggcaaatt ctgcgagtgt gataatttca
1741 actgtgatag atccaatggc ttaatttgtg gaggaaatgg tgtttgcaag tgtcgtgtgt
1801 gtgagtgcaa ccccaactac actggcagtg catgtgactg ttctttggat actagtactt
1861 gtgaagccag caacggacag atctgcaatg gccggggcat ctgtgagtgt ggtgtctgta
1921 agtgtacaga tccgaagttt caagggcaaa cgtgtgagat gtgtcagacc tgccttggtg
1981 tctgtgctga gcataaagaa tgtgttcagt gcagagcctt caataaagga gaaaagaaag
2041 acacatgcac acaggaatgt tcctatttta acattaccaa ggtagaaagt cgggacaaat
2101 taccccagcc ggtccaacct gatcctgtgt cccattgtaa ggagaaggat gttgacgact
2161 gttggttcta ttttacgtat tcagtgaatg ggaacaacga ggtcatggtt catgttgtgg
2221 agaatccaga gtgtcccact ggtccagaca tcattccaat tgtagctggt gtggttgctg
2281 gaattgttct tattggcctt gcattactgc tgatatggaa gcttttaatg ataattcatg
2341 acagaaggga gtttgctaaa tttgaaaagg agaaaatgaa tgccaaatgg gacacgggtg
2401 aaaatcctat ttataagagt gccgtaacaa ctgtggtcaa tccgaagtat gagggaaaat
2461 gagtactgcc cgtgcaaatc ccacaacact gaatgcaaag tagcaatttc catagtcaca
2521 gttaggtagc tttagggcaa tattgccatg gttttactca tgtgcaggtt ttgaaaatgt
2581 acaatatgta taatttttaa aatgttttat tattttgaaa ataatgttgt aattcatgcc
2641 agggactgac aaaagacttg agacaggatg gttattcttg tcagctaagg tcacattgtg
2701 cctttttgac cttttcttcc tggactattg aaatcaagct tattggatta agtgatattt
2761 ctatagcgat tgaaagggca atagttaaag taatgagcat gatgagagtt tctgttaatc
2821 atgtattaaa actgattttt agctttacaa atatgtcagt ttgcagttat gcagaatcca
2881 aagtaaatgt cctgctagct agttaaggat tgttttaaat ctgttatttt gctatttgcc
2941 tgttagacat gactgatgac atatctgaaa gacaagtatg ttgagagttg ctggtgtaaa
3001 atacgtttga aatagttgat ctacaaaggc catgggaaaa attcagagag ttaggaagga
3061 aaaaccaata gctttaaaac ctgtgtgcca ttttaagagt tacttaatgt ttggtaactt
3121 ttatgccttc actttacaaa ttcaagcctt agataaaaga accgagcaat tttctgctaa
3181 aaagtccttg atttagcact atttacatac aggccatact ttacaaagta tttgctgaat
3241 ggggaccttt tgagttgaat ttattttatt atttttattt tgtttaatgt ctggtgcttt
3301 ctatcacctc ttctaatctt ttaatgtatt tgtttgcaat tttggggtaa gacttttttt
3361 atgagtactt tttctttgaa gttttagcgg tcaatttgcc tttttaatga acatgtgaag
3421 ttatactgtg gctatgcaac agctctcacc tacgcgagtc ttactttgag ttagtgccat
3481 aacagaccac tgtatgttta cttctcacca tttgagttgc ccatcttgtt tcacactagt
3541 cacattcttg ttttaagtgc ctttagtttt aacagttcac tttttacagt gctatttact
3601 gaagttattt attaaatatg cctaaaatac ttaaatcgga aaaaaaaaaa aaaaaa
//