LOCUS BC019230 1208 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aldo-keto reductase family 1, member C3 (3-alpha
hydroxysteroid dehydrogenase, type II), mRNA (cDNA clone MGC:22807
IMAGE:3682448), complete cds.
ACCESSION BC019230
VERSION BC019230.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1208)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1208)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 31 Row: b Column: 24.
FEATURES Location/Qualifiers
source 1..1208
/db_xref="H-InvDB:HIT000038564"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22807 IMAGE:3682448"
/tissue_type="Bladder, carcinoma"
/clone_lib="NIH_MGC_53"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1208
/gene="AKR1C3"
/gene_synonym="DD3"
/gene_synonym="HA1753"
/gene_synonym="HAKRB"
/gene_synonym="HAKRe"
/gene_synonym="hluPGFS"
/gene_synonym="KIAA0119"
/db_xref="GeneID:8644"
/db_xref="HGNC:HGNC:386"
/db_xref="MIM:603966"
CDS 27..998
/gene="AKR1C3"
/gene_synonym="DD3"
/gene_synonym="HA1753"
/gene_synonym="HAKRB"
/gene_synonym="HAKRe"
/gene_synonym="hluPGFS"
/gene_synonym="KIAA0119"
/codon_start=1
/product="aldo-keto reductase family 1, member C3 (3-alpha
hydroxysteroid dehydrogenase, type II)"
/protein_id="AAH19230.1"
/db_xref="GeneID:8644"
/db_xref="HGNC:HGNC:386"
/db_xref="MIM:603966"
/translation="MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEA
GFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENS
LKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLA
KSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSA
LGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQR
IRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSDEY"
BASE COUNT 364 a 263 c 287 g 294 t
ORIGIN
1 ggggctagtc agacaagtga cagggaatgg attccaaaca ccagtgtgta aagctaaatg
61 atggccactt catgcctgta ttgggatttg gcacctatgc acctccagag gttccgagaa
121 gtaaagcttt ggaggtcaca aaattagcaa tagaagctgg gttccgccat atagattctg
181 ctcatttata caataatgag gagcaggttg gactggccat ccgaagcaag attgcagatg
241 gcagtgtgaa gagagaagac atattctaca cttcaaagct ttggtccact tttcatcgac
301 cagagttggt ccgaccagcc ttggaaaact cactgaagaa agctcaattg gactatgttg
361 acctctatct tattcattct ccaatgtctc taaagccagg tgaggaactt tcaccaacag
421 atgaaaatgg aaaagtaata tttgacatag tggatctctg taccacctgg gaggccatgg
481 agaagtgtaa ggatgcagga ttggccaagt ccattggggt gtcaaacttc aaccgcaggc
541 agctggagat gatcctcaac aagccaggac tcaagtacaa gcctgtctgc aaccaggtag
601 aatgtcatcc gtatttcaac cggagtaaat tgctagattt ctgcaagtcg aaagatattg
661 ttctggttgc ctatagtgct ctgggatctc aacgagacaa acgatgggtg gacccgaact
721 ccccggtgct cttggaggac ccagtccttt gtgccttggc aaaaaagcac aagcgaaccc
781 cagccctgat tgccctgcgc taccagctgc agcgtggggt tgtggtcctg gccaagagct
841 acaatgagca gcgcatcaga cagaacgtgc aggtttttga gttccagttg actgcagagg
901 acatgaaagc catagatggc ctagacagaa atctccacta ttttaacagt gatagttttg
961 ctagccaccc taattatcca tattcagatg aatattaaca tggagggctt tgcctgatgt
1021 ctaccagaag ccctgtgtgt ggatggtgac gcagaggacg tctctatgcc ggtgactgga
1081 catatcacct ctacttaaat ccgtcctgtt tagcgacttc agtcaactac agctgagtcc
1141 ataggccaga aagacaataa atttttatca ttttgaaata aaaaaaaaaa aaaaaaaaaa
1201 aaaaaaaa
//