LOCUS BC018926 2797 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens transient receptor potential cation channel, subfamily
V, member 2, mRNA (cDNA clone MGC:12549 IMAGE:4298484), complete
cds.
ACCESSION BC018926
VERSION BC018926.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2797)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2797)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC018926.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 17 Row: l Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 22547178.
FEATURES Location/Qualifiers
source 1..2797
/db_xref="H-InvDB:HIT000038475"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:12549 IMAGE:4298484"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2797
/gene="TRPV2"
/gene_synonym="MGC12549"
/gene_synonym="VRL"
/gene_synonym="VRL-1"
/gene_synonym="VRL1"
/db_xref="GeneID:51393"
/db_xref="HGNC:HGNC:18082"
/db_xref="MIM:606676"
CDS 368..2662
/gene="TRPV2"
/gene_synonym="MGC12549"
/gene_synonym="VRL"
/gene_synonym="VRL-1"
/gene_synonym="VRL1"
/codon_start=1
/product="transient receptor potential cation channel,
subfamily V, member 2"
/protein_id="AAH18926.1"
/db_xref="GeneID:51393"
/db_xref="HGNC:HGNC:18082"
/db_xref="MIM:606676"
/translation="MTSPSSSPVFRLETLDGGQEDGSEADRGKLDFGSGLPPMESQFQ
GEDRKFAPQIRVNLNYRKGTGASQPDPNRFDRDRLFNAVSRGVPEDLAGLPEYLSKTS
KYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDY
YRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAAC
TKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQA
GARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQREFSGLSHLSRKFTEWCYG
PVRVSLYDLASVDSCEENSVLEIIAFHCKSPHRHRMVVLEPLNKLLQAKWDLLIPKFF
LNFLCNLIYMFIFTAVAYHQPTLKKQAAPHLKAEVGNSMLLTGHILILLGGIYLLVGQ
LWYFWRRHVFIWISFIDSYFEILFLFQALLTVVSQVLCFLAIEWYLPLLVSALVLGWL
NLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLIYLVFLFGFAVALVSLSQEAWRPEAP
TGPNATESVQPMEGQEDEGNGAQYRGILEASLELFKFTIGMGELAFQEQLHFRGMVLL
LLLAYVLLTYILLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWCRKKQ
RAGVMLTVGTKPDGSPDERWCFRVEEVNWASWEQTLPTLCEDPSGAGVPRTLENPVLA
SPPKEDEDGASEENYVPVQLLQSN"
BASE COUNT 583 a 827 c 799 g 588 t
ORIGIN
1 ctctggtggc tagcctgtcc tgacagggga gagttaagct cccgttctcc accgtgccgg
61 ctggccaggt gggctgaggg tgaccgagag accagaacct gcttgctgga gcttagtgct
121 cagagctggg gagggaggtt ccgccgctcc tctgctgtca gcgccggcag cccctcccgg
181 cttcacttcc tcccgcagcc cctgctactg agaagctccg ggatcccagc agccgccacg
241 ccctggcctc agcctgcggg gctccagtca ggccaacacc gacgcgcagc tgggaggaag
301 acaggaccct tgacatctcc atctgcacag aggtcctggc tggaccgagc agcctcctcc
361 tcctaggatg acctcaccct ccagctctcc agttttcagg ttggagacat tagatggagg
421 ccaagaagat ggctctgagg cggacagagg aaagctggat tttgggagcg ggctgcctcc
481 catggagtca cagttccagg gcgaggaccg gaaattcgcc cctcagataa gagtcaacct
541 caactaccga aagggaacag gtgccagtca gccggatcca aaccgatttg accgagatcg
601 gctcttcaat gcggtctccc ggggtgtccc cgaggatctg gctggacttc cagagtacct
661 gagcaagacc agcaagtacc tcaccgactc ggaatacaca gagggctcca caggtaagac
721 gtgcctgatg aaggctgtgc tgaaccttaa ggacggagtc aatgcctgca ttctgccact
781 gctgcagatc gacagggact ctggcaatcc tcagcccctg gtaaatgccc agtgcacaga
841 tgactattac cgaggccaca gcgctctgca catcgccatt gagaagagga gtctgcagtg
901 tgtgaagctc ctggtggaga atggggccaa tgtgcatgcc cgggcctgcg gccgcttctt
961 ccagaagggc caagggactt gcttttattt cggtgagcta cccctctctt tggccgcttg
1021 caccaagcag tgggatgtgg taagctacct cctggagaac ccacaccagc ccgccagcct
1081 gcaggccact gactcccagg gcaacacagt cctgcatgcc ctagtgatga tctcggacaa
1141 ctcagctgag aacattgcac tggtgaccag catgtatgat gggctcctcc aagctggggc
1201 ccgcctctgc cctaccgtgc agcttgagga catccgcaac ctgcaggatc tcacgcctct
1261 gaagctggcc gccaaggagg gcaagatcga gattttcagg cacatcctgc agcgggagtt
1321 ttcaggactg agccaccttt cccgaaagtt caccgagtgg tgctatgggc ctgtccgggt
1381 gtcgctgtat gacctggctt ctgtggacag ctgtgaggag aactcagtgc tggagatcat
1441 tgcctttcat tgcaagagcc cgcaccgaca ccgaatggtc gttttggagc ccctgaacaa
1501 actgctgcag gcgaaatggg atctgctcat ccccaagttc ttcttaaact tcctgtgtaa
1561 tctgatctac atgttcatct tcaccgctgt tgcctaccat cagcctaccc tgaagaagca
1621 ggccgcccct cacctgaaag cggaggttgg aaactccatg ctgctgacgg gccacatcct
1681 tatcctgcta ggggggatct acctcctcgt gggccagctg tggtacttct ggcggcgcca
1741 cgtgttcatc tggatctcgt tcatagacag ctactttgaa atcctcttcc tgttccaggc
1801 cctgctcaca gtggtgtccc aggtgctgtg tttcctggcc atcgagtggt acctgcccct
1861 gcttgtgtct gcgctggtgc tgggctggct gaacctgctt tactatacac gtggcttcca
1921 gcacacaggc atctacagtg tcatgatcca gaaggtcatc ctgcgggacc tgctgcgctt
1981 ccttctgatc tacttagtct tccttttcgg cttcgctgta gccctggtga gcctgagcca
2041 ggaggcttgg cgccccgaag ctcctacagg ccccaatgcc acagagtcag tgcagcccat
2101 ggagggacag gaggacgagg gcaacggggc ccagtacagg ggtatcctgg aagcctcctt
2161 ggagctcttc aaattcacca tcggcatggg cgagctggcc ttccaggagc agctgcactt
2221 ccgcggcatg gtgctgctgc tgctgctggc ctacgtgctg ctcacctaca tcctgctgct
2281 caacatgctc atcgccctca tgagcgagac cgtcaacagt gtcgccactg acagctggag
2341 catctggaag ctgcagaaag ccatctctgt cctggagatg gagaatggct attggtggtg
2401 caggaagaag cagcgggcag gtgtgatgct gaccgttggc actaagccag atggcagccc
2461 cgatgagcgc tggtgcttca gggtggagga ggtgaactgg gcttcatggg agcagacgct
2521 gcctacgctg tgtgaggacc cgtcaggggc aggtgtccct cgaactctcg agaaccctgt
2581 cctggcttcc cctcccaagg aggatgagga tggtgcctct gaggaaaact atgtgcccgt
2641 ccagctcctc cagtccaact gatggcccag atgcagcagg aggccagagg acagagcaga
2701 ggatctttcc aaccacatct gctggctctg gggtcccagt gaattctggt ggcaaatata
2761 tattttcact aactaaaaaa aaaaaaaaaa aaaaaaa
//