LOCUS BC018759 2677 bp mRNA linear HUM 30-SEP-2003
DEFINITION Homo sapiens astrotactin 2, mRNA (cDNA clone IMAGE:4128621),
partial cds.
ACCESSION BC018759
VERSION BC018759.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2677)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2677)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC018759.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 40 Row: c Column: 14.
FEATURES Location/Qualifiers
source 1..2677
/db_xref="H-InvDB:HIT000089701"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4128621"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2677
/gene="ASTN2"
/gene_synonym="KIAA0634"
/db_xref="GeneID:23245"
CDS <1..2417
/gene="ASTN2"
/gene_synonym="KIAA0634"
/codon_start=3
/product="ASTN2 protein"
/protein_id="AAH18759.2"
/db_xref="GeneID:23245"
/translation="ECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLVTG
EQAPEKILSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLST
YFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCY
DHSKGIDCSDGFNGGCEQLCLQQTLPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLML
SDVCEGPKCLKPDSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLA
DGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLS
TITLAAGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQ
QLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPS
TCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVI
DDWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDY
ILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCL
EPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKE
QQMAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSS
HCSSLLRSAYIQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNTY
GESKGR"
misc_feature 948..1502
/gene="ASTN2"
/gene_synonym="KIAA0634"
/note="MACPF; Region: membrane-attack complex / perforin"
/db_xref="CDD:smart00457"
BASE COUNT 632 a 711 c 750 g 584 t
ORIGIN
1 gagagtgcag ctgtcatgaa ggctatgccc ctgaccctgt tcacagacat ctgtgtgtgc
61 gcagtgactg gggacagagt gaaggacctt ggccctacac gacacttgag aggggctatg
121 atctggtgac aggggagcaa gcccctgaaa agattctcag cttgggccaa ggcctctggc
181 ttcctgtcag caaaagcttt gtggttccgc ctgtggagct gtccatcaac cccctggcca
241 gctgcaagac cgatgtgctc gtcacggaag accctgcaga tgtcagggaa gaagcgatgc
301 tgtccacata ctttgaaacc atcaatgacc tgctgtcttc cttcgggcca gttcgtgact
361 gctctcggaa caatgggggc tgcactcgca acttcaagtg tgtgtctgac cggcaggtgg
421 attcctcggg atgtgtgtgc cctgaggagc tgaaacccat gaaggatggc tctggctgct
481 acgaccactc caaaggcatt gactgctctg atggctttaa tggcggctgt gagcagctgt
541 gcctgcagca gacgctgccc ctgccctacg atgccacttc gagcaccatc ttcatgttct
601 gcggttgcgt ggaggagtac aaactggctc ctgatggaaa atcctgctta atgctctcag
661 atgtctgcga gggccccaag tgcctcaaac ctgactccaa attcaatgat accctctttg
721 gagagatgct acatggttac aacaaccgga cccagcatgt gaaccaaggc caagtcttcc
781 agatgacctt tagggagaac aacttcatca aggactttcc ccagctggcc gatgggctgt
841 tggtgatccc gctgccggtg gaggagcagt gccggggggt cctctccgag ccccttccgg
901 acctccaact gctcactgga gatatcaggt atgatgaggc catgggttac cccatggtgc
961 agcagtggcg ggtccggagc aacctctacc gtgtgaagct cagcaccatc accctcgcag
1021 caggcttcac taatgttctc aagatcctga ccaaggagag cagtcgggag gagctgctgt
1081 ccttcatcca gcactatggc tcccactaca tcgcagaggc cctctatggc tcagagctca
1141 cctgcatcat ccactttccc agcaagaagg tccagcagca gctgtggctc cagtatcaga
1201 aagagaccac agagctgggc agcaagaagg agctcaagtc catgcccttc atcacctacc
1261 tctcaggttt gctgacagcc cagatgctgt cagatgacca gctcatttca ggtgtggaga
1321 ttcgctgtga ggagaagggg cgctgtccat ctacctgtca cctttgccgc cggccaggca
1381 aggagcagct gagccccaca ccagtgctgc tggaaatcaa ccgtgtggtg ccactttata
1441 ccctcatcca agacaatggc acaaaggagg ccttcaagag tgcactgatg agttcctact
1501 ggtgctcagg gaaaggggat gtgatcgatg actggtgcag gtgtgacctc agcgcctttg
1561 atgccaatgg gctccccaac tgcagccccc ttctgcagcc ggtgctgcgg ctgtccccaa
1621 cagtggagcc ctccagtact gtggtctcct tggagtgggt ggatgttcag ccagctattg
1681 ggaccaaggt ctccgactat attctgcagc ataagaaagt ggatgaatac acagacactg
1741 acctgtacac aggagaattc ctgagttttg ctgatgactt actctctggc ctgggcacat
1801 cttgtgtagc agctggtcga agccatggag aggtccctga agtcagtatc tactcagtca
1861 tcttcaagtg tctggagccc gacggtctct acaagttcac tctgtatgct gtggatacac
1921 gagggaggca ctcagagcta agcacggtga ccctgaggac ggcctgtcca ctggtagatg
1981 acaacaaggc agaagaaata gctgacaaga tctacaatct gtacaatggg tacacaagtg
2041 gaaaggagca gcagatggcc tacaacacac tgatggaggt ctcagcctcg atgctgttcc
2101 gagtccagca ccactacaac tctcactatg aaaagtttgg cgacttcgtc tggagaagtg
2161 aggatgagct ggggcccagg aaggcccacc tgattctacg gcgactggag agggtgagta
2221 gccactgctc cagcctcctg cggagtgcct acatccagag ccgcgtggaa acagtgccct
2281 atcttttctg ccgcagcgag gaggtccggc ctgcaggcat ggtgtggtat agcatcctca
2341 aggacaccaa aatcacgtgt gaggagaaga tggtgtcaat ggcccgaaac acgtacgggg
2401 agtccaaggg ccggtgaggg agggtattgc cctccgtgag cacagagact ctccatggga
2461 gggggagcag tattctcctg gatcctgggg cctgggtggg ctgggggaca gctgaggatg
2521 ggcctagcag atgaagcttg ccagcaaggc caaagcaaac ggtttctcct gtggatagtg
2581 gacagagacc tttgtaacca atggaattat tcatttttct ctatctttta ttttttcaaa
2641 gatattattt gactctaaaa aaaaaaaaaa aaaaaaa
//