LOCUS BC018739 3702 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens budding uninhibited by benzimidazoles 1 homolog beta
(yeast), mRNA (cDNA clone MGC:31884 IMAGE:4649881), complete cds.
ACCESSION BC018739
VERSION BC018739.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3702)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3702)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 40 Row: g Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 59814246.
FEATURES Location/Qualifiers
source 1..3702
/db_xref="H-InvDB:HIT000038433"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:31884 IMAGE:4649881"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3702
/gene="BUB1B"
/gene_synonym="Bub1A"
/gene_synonym="BUB1beta"
/gene_synonym="BUBR1"
/gene_synonym="hBUBR1"
/gene_synonym="MAD3L"
/gene_synonym="SSK1"
/db_xref="GeneID:701"
/db_xref="HGNC:HGNC:1149"
/db_xref="MIM:602860"
CDS 135..3287
/gene="BUB1B"
/gene_synonym="Bub1A"
/gene_synonym="BUB1beta"
/gene_synonym="BUBR1"
/gene_synonym="hBUBR1"
/gene_synonym="MAD3L"
/gene_synonym="SSK1"
/codon_start=1
/product="budding uninhibited by benzimidazoles 1 homolog
beta (yeast)"
/protein_id="AAH18739.1"
/db_xref="GeneID:701"
/db_xref="HGNC:HGNC:1149"
/db_xref="MIM:602860"
/translation="MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGA
LAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLL
ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAE
EYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFE
SSVPQRSTLAELKSKGKKTARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFD
ENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVP
AVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDSLQRVQSHQQASEEK
KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME
KKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTLSSSVCQVNCCARET
SLAENIWQEQPHSKGPSVPFSIFDEFLLSEKKNKSPPADPPRVLAQRRPLAVLKTSES
ITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVTICPNPEDTCDFARAARFVSTPFHE
IMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIYSQTLSIKKLSPIIEDSREATHS
SGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQSPWCSQYRRQLLKSLPELSAS
AELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKLFWVAPRNSAELTVIKVSS
QPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYINCFTLQDLLQHSEYITH
EITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDCNKNNQALKIVDFSY
SVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQVF
WDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMNGVFDTTFQSH
LNKALWKVGKLTSPGALLFQ"
BASE COUNT 1179 a 738 c 829 g 956 t
ORIGIN
1 gtttgttagg gagtcgtgtg cgtgccttgg tcgcttctgt agctccgagg gcaggttgcg
61 gaagaaagcc caggcggtct gtggcccaga ggaaaggcct gcagcaggac gaggacctga
121 gccaggaatg caggatggcg gcggtgaaga aggaaggggg tgctctgagt gaagccatgt
181 ccctggaggg agatgaatgg gaactgagta aagaaaatgt acaaccttta aggcaagggc
241 ggatcatgtc cacgcttcag ggagcactgg cacaagaatc tgcctgtaac aatactcttc
301 agcagcagaa acgggcattt gaatatgaaa ttcgatttta cactggaaat gaccctctgg
361 atgtttggga taggtatatc agctggacag agcagaacta tcctcaaggt gggaaggaga
421 gtaatatgtc aacgttatta gaaagagctg tagaagcact acaaggagaa aaacgatatt
481 atagtgatcc tcgatttctc aatctctggc ttaaattagg gcgtttatgc aatgagcctt
541 tggatatgta cagttacttg cacaaccaag ggattggtgt ttcacttgct cagttctata
601 tctcatgggc agaagaatat gaagctagag aaaactttag gaaagcagat gcgatatttc
661 aggaagggat tcaacagaag gctgaaccac tagaaagact acagtcccag caccgacaat
721 tccaagctcg agtgtctcgg caaactctgt tggcacttga gaaagaagaa gaggaggaag
781 tttttgagtc ttctgtacca caacgaagca cactagctga actaaagagc aaagggaaaa
841 agacagcaag agctccaatc atccgtgtag gaggtgctct caaggctcca agccagaaca
901 gaggactcca aaatccattt cctcaacaga tgcaaaataa tagtagaatt actgtttttg
961 atgaaaatgc tgatgaggct tctacagcag agttgtctaa gcctacagtc cagccatgga
1021 tagcaccccc catgcccagg gccaaagaga atgagctgca agcaggccct tggaacacag
1081 gcaggtcctt ggaacacagg cctcgtggca atacagcttc actgatagct gtacccgctg
1141 tgcttcccag tttcactcca tatgtggaag agactgcaca acagccagtt atgacaccat
1201 gtaaaattga acctagtata aaccacatcc taagcaccag aaagcctgga aaggaagaag
1261 gagattctct acaaagggtt cagagccatc agcaagcgtc tgaggagaag aaagagaaga
1321 tgatgtattg taaggagaag atttatgcag gagtagggga attctccttt gaagaaattc
1381 gggctgaagt tttccggaag aaattaaaag agcaaaggga agccgagcta ttgaccagtg
1441 cagagaagag agcagaaatg cagaaacaga ttgaagagat ggagaagaag ctaaaagaaa
1501 tccaaactac tcagcaagaa agaacaggtg atcagcaaga agagacgatg cctacaaagg
1561 agacaactaa actgcaaatt gcttccgagt ctcagaaaat accaggaatg actctatcca
1621 gttctgtttg tcaagtaaac tgttgtgcca gagaaacttc acttgcggag aacatttggc
1681 aggaacaacc tcattctaaa ggtcccagtg tacctttctc catttttgat gagtttcttc
1741 tttcagaaaa gaagaataaa agtcctcctg cagatccccc acgagtttta gctcaacgaa
1801 gaccccttgc agttctcaaa acctcagaaa gcatcacctc aaatgaagat gtgtctccag
1861 atgtttgtga tgaatttaca ggaattgaac ccttgagcga ggatgccatt atcacaggct
1921 tcagaaatgt aacaatttgt cctaacccag aagacacttg tgactttgcc agagcagctc
1981 gttttgtatc cactcctttt catgagataa tgtccttgaa ggatctccct tctgatcctg
2041 agagactgtt accggaagaa gatctagatg taaagacctc tgaggaccag cagacagctt
2101 gtggcactat ctacagtcag actctcagca tcaagaagct gagcccaatt attgaagaca
2161 gtcgtgaagc cacacactcc tctggcttct ctggttcttc tgcctcggtt gcaagcacct
2221 cctccatcaa atgtcttcaa attcctgaga aactagaact tactaatgag acttcagaaa
2281 accctactca gtcaccatgg tgttcacagt atcgcagaca gctactgaag tccctaccag
2341 agttaagtgc ctctgcagag ttgtgtatag aagacagacc aatgcctaag ttggaaattg
2401 agaaggaaat tgaattaggt aatgaggatt actgcattaa acgagaatac ctaatatgtg
2461 aagattacaa gttattctgg gtggcgccaa gaaactctgc agaattaaca gtaataaagg
2521 tatcttctca acctgtccca tgggactttt atatcaacct caagttaaag gaacgtttaa
2581 atgaagattt tgatcatttt tgcagctgtt atcaatatca agatggctgt attgtttggc
2641 accaatatat aaactgcttc acccttcagg atcttctcca acacagtgaa tatattaccc
2701 atgaaataac agtgttgatt atttataacc ttttgacaat agtggagatg ctacacaaag
2761 cagaaatagt ccatggtgac ttgagtccaa ggtgtctgat tctcagaaac agaatccacg
2821 atccctatga ttgtaacaag aacaatcaag ctttgaagat agtggacttt tcctacagtg
2881 ttgaccttag ggtgcagctg gatgttttta ccctcagcgg ctttcggact gtacagatcc
2941 tggaaggaca aaagatcctg gctaactgtt cttctcccta ccaggtagac ctgtttggta
3001 tagcagattt agcacattta ctattgttca aggaacacct acaggtcttc tgggatgggt
3061 ccttctggaa acttagccaa aatatttctg agctaaaaga tggtgaattg tggaataaat
3121 tctttgtgcg gattctgaat gccaatgatg aggccacagt gtctgttctt ggggagcttg
3181 cagcagaaat gaatggggtt tttgacacta cattccaaag tcacctgaac aaagccttat
3241 ggaaggtagg gaagttaact agtcctgggg ctttgctctt tcagtgagct aggcaatcaa
3301 gtctcacaga ttgctgcctc agagcaatgg ttgtattgtg gaacactgaa actgtatgtg
3361 ctgtaattta atttaggaca catttagatg cactaccatt gctgttctac tttttggtac
3421 aggtatattt tgacgtcact gatatttttt atacagtgat atacttactc atggccttgt
3481 ctaacttttg tgaagaacta ttttattcta aacagactca ttacaaatgg ttaccttgtt
3541 atttaaccca tttgtctcta cttttccctg tacttttccc atttgtaatt tgtaaaatgt
3601 tctcttatga tcaccatgta ttttgtaaat aataaaatag tatctgttaa aaaaaaaaaa
3661 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//