LOCUS BC018727 2815 bp mRNA linear HUM 27-APR-2005
DEFINITION Homo sapiens eukaryotic translation initiation factor 2C, 2, mRNA
(cDNA clone IMAGE:3356425), partial cds.
ACCESSION BC018727
VERSION BC018727.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2815)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2815)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: a Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 29171733.
FEATURES Location/Qualifiers
source 1..2815
/db_xref="H-InvDB:HIT000038425"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3356425"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2815
/gene="EIF2C2"
/gene_synonym="AGO2"
/gene_synonym="MGC3183"
/gene_synonym="Q10"
/db_xref="GeneID:27161"
/db_xref="MIM:606229"
CDS <1..1868
/gene="EIF2C2"
/gene_synonym="AGO2"
/gene_synonym="MGC3183"
/gene_synonym="Q10"
/codon_start=3
/product="EIF2C2 protein"
/protein_id="AAH18727.2"
/db_xref="GeneID:27161"
/db_xref="MIM:606229"
/translation="DFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVC
NVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLP
LEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFG
IMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACF
APQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAG
LQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLG
GVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVR
VQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIR
EACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEF
DFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAY
YAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"
BASE COUNT 782 a 736 c 703 g 594 t
ORIGIN
1 tggattttaa aagtattgaa gaacaacaaa aacctctgac agattcccaa agggtaaagt
61 ttaccaaaga aattaaaggt ctaaaggtgg agataacgca ctgtgggcag atgaagagga
121 agtaccgtgt ctgcaatgtg acccggcggc ccgccagtca ccaaacattc ccgctgcagc
181 aggagagcgg gcagacggtg gagtgcacgg tggcccagta tttcaaggac aggcacaagt
241 tggttctgcg ctacccccac ctcccatgtt tacaagtcgg acaggagcag aaacacacct
301 accttcccct ggaggtctgt aacattgtgg caggacaaag atgtattaaa aaattaacgg
361 acaatcagac ctcaaccatg atcagagcaa ctgctaggtc ggcgcccgat cggcaagaag
421 agattagcaa attgatgcga agtgcaagtt tcaacacaga tccatacgtc cgtgaatttg
481 gaatcatggt caaagatgag atgacagacg tgactgggcg ggtgctgcag ccgccctcca
541 tcctctacgg gggcaggaat aaagctattg cgacccctgt ccagggcgtc tgggacatgc
601 ggaacaagca gttccacacg ggcatcgaga tcaaggtgtg ggccattgcg tgcttcgccc
661 cccagcgcca gtgcacggaa gtccatctga agtccttcac agagcagctc agaaagatct
721 cgagagacgc tggcatgccc atccagggcc agccgtgctt ctgcaaatac gcgcaggggg
781 cggacagcgt ggagcccatg ttccggcacc tgaagaacac gtatgcgggc ctgcagctgg
841 tggtggtcat cctgcccggc aagacgcccg tgtacgccga ggtcaagcgc gtgggagaca
901 cggtgctggg gatggccacg cagtgcgtgc agatgaagaa cgtgcagagg accacgccac
961 agaccctgtc caacctctgc ctgaagatca acgtcaagct gggaggcgtg aacaacatcc
1021 tgctgcccca gggcaggccg ccggtgttcc agcagcccgt catctttctg ggagcagacg
1081 tcactcaccc ccccgccggg gatgggaaga agccctccat tgccgccgtg gtgggcagca
1141 tggacgccca ccccaatcgc tactgcgcca ccgtgcgcgt gcagcagcac cggcaggaga
1201 tcatacaaga cctggccgcc atggtccgcg agctcctcat ccagttctac aagtccacgc
1261 gcttcaagcc cacccgcatc atcttctacc gcgacggtgt ctctgaaggc cagttccagc
1321 aggttctcca ccacgagttg ctggccatcc gtgaggcctg tatcaagcta gaaaaagact
1381 accagcccgg gatcaccttc atcgtggtgc agaagaggca ccacacccgg ctcttctgca
1441 ctgacaagaa cgagcgggtt gggaaaagtg gaaacattcc agcaggcacg actgtggaca
1501 cgaaaatcac ccaccccacc gagttcgact tctacctgtg tagtcacgct ggcatccagg
1561 ggacaagcag gccttcgcac tatcacgtcc tctgggacga caatcgtttc tcctctgatg
1621 agctgcagat cctaacctac cagctgtgtc acacctacgt gcgctgcaca cgctccgtgt
1681 ccatcccagc gccagcatac tacgctcacc tggtggcctt ccgggccagg taccacctgg
1741 tggataagga acatgacagt gctgaaggaa gccatacctc tgggcagagt aacgggcgag
1801 accaccaagc actggccaag gcggtccagg ttcaccaaga cactctgcgc accatgtact
1861 ttgcttgaca tgttttagtg tttagcgatt gtgtaccgag tgggattcac gagaccagct
1921 acactcagac caacagatgg ccagcccttc cgtgacagcc agcatcgaac atgagacgtc
1981 attgatttta ttagattctc cgttttccag aatgccttcc gtcccagatt tcaaacttgg
2041 attttgaact gcagacctgt atgagaaccc aatgtcatag gaaatatggt ttgctaaaat
2101 ctataagctg cttattaaaa cagagtcccg tgtgtcctaa aaatctccta aaaccagtct
2161 atgaactcag ggctttaaaa catttttaat ttatttggtc attcaattta cttgttttta
2221 atacatgatt ctctatgaaa ttgatgggct caaactagct gtgaatcttc tgagagtgaa
2281 agcaacacaa aacacaagtg tggttttaaa gccttgaaca ttctgatgtt gtcactaaag
2341 ttgatttcca ggcgatgctc gtgtgcccct ggcgtggctc acccaagttc ctcgactgag
2401 ggccggtggc catgcagagg cgtccgcagg tgccgtgttc tgccagcacc gcccttcacc
2461 cggcctgaac taaggagcag tggcagaagg tgggccccgt gtgtttacag catttccagg
2521 tccagagagg ttggcagaca agtgccattt taataaaaaa tgtatttaaa aaaagaaaaa
2581 agacaatata ctgacagtct aatcatcaga tttgtcctat aggactgtga catttatttt
2641 ccaaagtttt taaagaatac gggtctgtgg tgataaatac agtacaatcc tttttcactg
2701 ttatgtcttt aatgtaagag aagaatatat atatctggtt tgcagtaaaa aaaaaaaaaa
2761 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//