LOCUS BC018726 1327 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens CD74 molecule, major histocompatibility complex, class
II invariant chain, mRNA (cDNA clone MGC:31825 IMAGE:4853578),
complete cds.
ACCESSION BC018726
VERSION BC018726.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1327)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1327)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 40 Row: i Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 68448543.
FEATURES Location/Qualifiers
source 1..1327
/db_xref="H-InvDB:HIT000038424"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:31825 IMAGE:4853578"
/tissue_type="Primary B-Cells from Tonsils"
/clone_lib="NIH_MGC_48"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1327
/gene="CD74"
/gene_synonym="HLADG"
/gene_synonym="Ia-GAMMA"
/gene_synonym="protein 41"
/db_xref="GeneID:972"
/db_xref="HGNC:HGNC:1697"
/db_xref="MIM:142790"
CDS 12..710
/gene="CD74"
/gene_synonym="HLADG"
/gene_synonym="Ia-GAMMA"
/gene_synonym="protein 41"
/codon_start=1
/product="CD74 molecule, major histocompatibility complex,
class II invariant chain"
/protein_id="AAH18726.1"
/db_xref="GeneID:972"
/db_xref="HGNC:HGNC:1697"
/db_xref="MIM:142790"
/translation="MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKC
SRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPK
PVSKMRMATPLLMQALPMGALPQGPMQNATKYGNMTEDHVMHLLQNADPLKVYPPLKG
SFPENLRHLKNTMETIDWKVFESWMHHWLLFEMSRHSLEQKPTDAPPKESLELEDPSS
GLGVTKQDLGPVPM"
BASE COUNT 326 a 431 c 327 g 243 t
ORIGIN
1 cagggtccca gatgcacagg aggagaagca ggagctgtcg ggaagatcag aagccagtca
61 tggatgacca gcgcgacctt atctccaaca atgagcaact gcccatgctg ggccggcgcc
121 ctggggcccc ggagagcaag tgcagccgcg gagccctgta cacaggcttt tccatcctgg
181 tgactctgct cctcgctggc caggccacca ccgcctactt cctgtaccag cagcagggcc
241 ggctggacaa actgacagtc acctcccaga acctgcagct ggagaacctg cgcatgaagc
301 ttcccaagcc tcccaagcct gtgagcaaga tgcgcatggc caccccgctg ctgatgcagg
361 cgctgcccat gggagccctg ccccaggggc ccatgcagaa tgccaccaag tatggcaaca
421 tgacagagga ccatgtgatg cacctgctcc agaatgctga ccccctgaag gtgtacccgc
481 cactgaaggg gagcttcccg gagaacctga gacaccttaa gaacaccatg gagaccatag
541 actggaaggt ctttgagagc tggatgcacc attggctcct gtttgaaatg agcaggcact
601 ccttggagca aaagcccact gacgctccac cgaaagagtc actggaactg gaggacccgt
661 cttctgggct gggtgtgacc aagcaggatc tgggcccagt ccccatgtga gagcagcaga
721 ggcggtcttc aacatcctgc cagccccaca cagctacagc tttcttgctc ccttcagccc
781 ccagcccctc ccccatctcc caccctgtac ctcatcccat gagaccctgg tgcctggctc
841 tttcgtcacc cttggacaag acaaaccaag tcggaacagc agataacaat gcagcaaggc
901 cctgctgccc aatctccatc tgtcaacagg ggcgtgaggt cccaggaagt ggccaaaagc
961 tagacagatc cccgttcctg acatcacagc agcctccaac acaaggctcc aagacctagg
1021 ctcatggacg agatgggaag gcacagggag aagggataac cctacaccca gaccccaggc
1081 tggacatgct gactgtcctc tcccctccag cctttggcct tggcttttct agcctattta
1141 cctgcaggct gagccactct cttccctttc cccagcatca ctccccaagg aagagccaat
1201 gttttccacc cataatcctt tctgccgacc cctagttccc tctgctcagc caagcttgtt
1261 atcagctttc agggccatgg ttcacattag aataaaaggt agtaattaga aaaaaaaaaa
1321 aaaaaaa
//