LOCUS BC018509 3179 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens core-binding factor, beta subunit, mRNA (cDNA clone
MGC:9276 IMAGE:3867061), complete cds.
ACCESSION BC018509
VERSION BC018509.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3179)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3179)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 13 Row: f Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47132615.
FEATURES Location/Qualifiers
source 1..3179
/db_xref="H-InvDB:HIT000038355"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9276 IMAGE:3867061"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3179
/gene="CBFB"
/gene_synonym="PEBP2B"
/db_xref="GeneID:865"
/db_xref="HGNC:HGNC:1539"
/db_xref="MIM:121360"
CDS 262..810
/gene="CBFB"
/gene_synonym="PEBP2B"
/codon_start=1
/product="core-binding factor, beta subunit"
/protein_id="AAH18509.1"
/db_xref="GeneID:865"
/db_xref="HGNC:HGNC:1539"
/db_xref="MIM:121360"
/translation="MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQARF
QNACRDGRSEIAFVATGTNLSLQFFPASWQGEQRQTPSREYVDLEREAGKVYLKAPMI
LNGVCVIWKGWIDLQRLDGMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSH
REEMEVRVSQLLAVTGKKTTRP"
BASE COUNT 898 a 581 c 692 g 1008 t
ORIGIN
1 gcggtgagcg ctggggctgc gcgggcggca ggcaacggct gaggcggcgg cggcggcggc
61 ggcggcgtgg gttgggctcg agcgggcggc ggcgcctcag actccccgga acgggagccc
121 acgcgggcgg gcgcctgaaa caaagggaag cgggcgtccg ggcgccgcgg gtgggcggtc
181 agtcggtcag cgcggagcca gccagcgggt gcccgcgcaa gccccgagcg cggccggccg
241 gcgcggcctc agggcgggaa gatgccgcgc gtcgtgcccg accagagaag caagttcgag
301 aacgaggagt tttttaggaa gctgagccgc gagtgtgaga ttaagtacac gggcttcagg
361 gaccggcccc acgaggaacg ccaggcacgc ttccagaacg cctgccgcga cggccgctcg
421 gaaatcgctt ttgtggccac aggaaccaat ctgtctctcc agttttttcc ggccagctgg
481 cagggagaac agcgacaaac acctagccga gagtatgtcg acttagaaag agaagcaggc
541 aaggtatatt tgaaggctcc catgattctg aatggagtct gtgttatctg gaaaggctgg
601 attgatctcc aaagactgga tggtatgggc tgtctggagt ttgatgagga gcgagcccag
661 caggaggatg cattagcaca acaggccttt gaagaggctc ggagaaggac acgcgaattt
721 gaagatagag acaggtctca tcgggaggaa atggaggtga gagtttcaca gctgctggca
781 gtaactggca agaagacaac aagaccctag tcctggttcc aatttaggtg gtggtgatga
841 cctcaaactt cgttaattaa tagcacagca gatgtgtgct gcccatcttt acatacacat
901 tgcttctagt tggcagaaat aattgattaa aagaccagaa actgtgataa ctggaggtac
961 tacggtctat ttctcaacct taggcagtaa tagacatcac aaactgccat ggttttgcac
1021 tatgattata atacctgcat ttctaatttt ttaagcatgt agccagtaat aatttgaagt
1081 tttttttcta tgcaagctta ccttgttggc attattttag ggagttgaaa ctatcaactg
1141 taaagctcct tttcttccac tttaatttaa aagttcatgt catttaaaaa caagtcaaga
1201 aattaaaatt gtatcagagg gttttctcta atcatttttt ctattttttt ttgtacttct
1261 agatgttttg gttatacagc ttcattttag atgagcattc ttattttttg ttttgtttgc
1321 cccatttcct tttgtgtttt tatagtctat agcattttaa aactgctgat gttgtttgca
1381 ttatttacag gctaaaaact tagtagcata gagctgtctg ccacagcctt ctgacaaagt
1441 ttacagttat taaagttgca gtatcctttt aaatgctagt aatcagcact ctttcttttt
1501 ttttttttta atagagacag ggtctcgcag tgttgcccag gctggtctcg aactcctggc
1561 atcaagcgat cctcctgcct tagcctccca gagtactggg attacaggct ctttcttttt
1621 aaacataaaa gttttaaatt ggtattaact ctgtactctg ccctagattg ttttagcttc
1681 tgttctgtaa tcatgagttt ggttggagat attctccata gatgatcttc tactgaaatg
1741 cctaaagaag tcacaggctg gcttctgttt tattcaggga tttttttaaa aagtcaatca
1801 gaaaagggat actggagctt cttcatgtat gtaacagcat attaaactgg agacagtgat
1861 gaatcagcta caaaggtaat attgtattaa aatcatgttt aagatagctg cttttatgtg
1921 tattttatat tgcatgcttt tgtaaaaaca tgctgggtga tgaaagatta gttttagaga
1981 gaaaatgttc atctgtgcag aggatgcatt ttcttccatt aattctggaa aaaacgttca
2041 cagttatata tatggtattt tgcaaaagga ctattaatag aaccttttga gatgaattaa
2101 tgtaagaata ttttttaaat aggcttactg tcaaattgca actttttttt tagatacaga
2161 gtggaaaaca gtgctaagtc atttggcacc tccttacaaa tatttttcat ggtcacattt
2221 attaaatgtt actacatttc tgaatttttg aaaaatgtat tttatcatta aatggcatta
2281 ttttaaaggg tgaaaaactg acacagtcaa ttcagaaaat ggactgaagt ctgaataagg
2341 tcattgcatt taaaaagcat ataactgtac ttgactgatg agggaggtgt tactttcatt
2401 gtatataggt cttatttcat aaacagatat cctgtatcaa ataaaagtat ttgttatata
2461 tttgaagtta tgcatggaaa ggagtgtgtt taaattgtta caaacaataa tgcgtcatta
2521 aaggccatgc tgatcttgca taactataag tactatgaat gaatttggtt ggttttggtg
2581 ttgtacagct cacatgttta cacactcagt gccctaattt cccctgaggg aatcgctttt
2641 taagtgatcc ttacagtggt gttttatgtt actttattac agagctcctt ggttttttac
2701 ttctgcactt aaattttttt aaataacatg atgatggtac attttcctct attgtctagc
2761 taagggcttt cggtccacca gtaaataaga tcaaatgctc ttaaatgttc ctgttaccat
2821 cctaatgtaa atactggatt tttctgtcat ttagcaccat gctgcttctg tctgtcttaa
2881 tgctggcatt aagatcatga gccctttttc tccagtagta caggctttga aaactacttc
2941 tattaagtta ttgatgcaat ttgatatttt ttcataatct atatttaaac aaaattacat
3001 cattgcatca tcttttctaa attcatctcc attaaaactt gccttaagct accagattgc
3061 ttttgccacc attggccata ctgtgtgttt gtttgtttaa tttactttca caataaactt
3121 ctgtgtagta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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