LOCUS BC017785 1817 bp mRNA linear HUM 21-OCT-2003
DEFINITION Homo sapiens protein tyrosine phosphatase, non-receptor type 22
(lymphoid), mRNA (cDNA clone IMAGE:4666653), complete cds.
ACCESSION BC017785
VERSION BC017785.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1817)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1817)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 36 Row: j Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 15619017
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1817
/db_xref="H-InvDB:HIT000038132"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4666653"
/tissue_type="Prostate, adenocarcinoma."
/clone_lib="NIH_MGC_60"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1817
/gene="PTPN22"
/gene_synonym="LYP"
/gene_synonym="Lyp1"
/gene_synonym="Lyp2"
/db_xref="GeneID:26191"
/db_xref="MIM:606986"
CDS 90..629
/gene="PTPN22"
/gene_synonym="LYP"
/gene_synonym="Lyp1"
/gene_synonym="Lyp2"
/codon_start=1
/product="PTPN22 protein"
/protein_id="AAH17785.1"
/db_xref="GeneID:26191"
/db_xref="MIM:606986"
/translation="MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTY
PTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIAT
QGPLSTTLLDFWRMIWEYSVLIIVMACMEYEMGKEAEKRKSDYIIRTLKVKFNSVSVI
LAHQTSLQNLFSQITPAHF"
misc_feature 159..563
/gene="PTPN22"
/gene_synonym="LYP"
/gene_synonym="Lyp1"
/gene_synonym="Lyp2"
/note="PTPc; Region: Protein tyrosine phosphatase,
catalytic domain"
/db_xref="CDD:smart00194"
BASE COUNT 660 a 292 c 286 g 579 t
ORIGIN
1 agtggctttt tggaggtgtc tcggccatga cacacatttg acatgccctc cctcaaccta
61 cttatagact atttttcttg ctctgcagca tggaccaaag agaaattctg cagaagttcc
121 tggatgaggc ccaaagcaag aaaattacta aagaggagtt tgccaatgaa tttctgaagc
181 tgaaaaggca atctaccaag tacaaggcag acaaaaccta tcctacaact gtggctgaga
241 agcccaagaa tatcaagaaa aacagatata aggatatttt gccctatgat tatagccggg
301 tagaactatc cctgataacc tctgatgagg attccagcta catcaatgcc aacttcatta
361 agggagttta tggacccaag gcttatattg ccacccaggg tcctttatct acaaccctcc
421 tggacttctg gaggatgatt tgggaatata gtgtccttat cattgttatg gcatgcatgg
481 agtatgaaat gggaaaggaa gctgaaaaaa ggaaatctga ttatataatc aggactctaa
541 aagttaagtt caatagtgta tctgtaattc ttgcccacca aacaagcctg cagaatctgt
601 tcagtcaaat aactccagct catttctgaa ttttggtttt gcaaaccgtt tttcaaaacc
661 caaaggacca aggaatccac caccaacttg gaatatttaa taaaactcca gatttataat
721 aatatgggct gcaagtacac ctgcaaataa aactactaga atactgctag ttaaaataag
781 tgctctatat gcataatatc aaatatgaag atatgctaat gtgttaatag cttttaaaag
841 aaaagcaaaa tgccaataag tgccagtttt gcattttcat atcatttgca ttgagttgaa
901 aactgcaaat aaaagtttgt cacttgagct tatgtacaga atgctatatg agaaacactt
961 ttagaatgga tttatttttc atttttgcca gttattttta ttttctttta cttttttaca
1021 taaacataaa cttcaaaagg tttgtaagat ttggatctca actaatttct acattgccag
1081 aatatactat aaaaagttaa aaaaaaaact tactttgtgg gttgcaatac aaactgctct
1141 tgacaatgac tattccctga cagttatttt tgcctaaatg gagtatacct tgtaaatctt
1201 cccaaatgtt gtggaaaact ggaatattaa gaaaatgaga aattatattt attagaataa
1261 aatgtgcaaa taatgacaat tatttgaatg taacaaggaa ttcaactgaa atcctgataa
1321 gttttaacca aagtcattaa attaccaatt ctagaaaagt aatcaatgaa atataatagc
1381 tatcttttgg tagcaaaaga tataaattgt atatgtttat acaggatctt tcagatcatg
1441 tgcaattttt atctaaccaa tcagaaatac tagtttaaaa tgaatttcta tatgaatatg
1501 gatctgccat aagaaaatct agttcaactc taattttatg tagtaaataa attggcaggt
1561 aattgttttt acaaagaatc cacctgactt cccctaatgc attaaaaata tttttattta
1621 aataacttta tttataactt ttagaaacat gtagtattgt ttaaacatca tttgttcttc
1681 agtatttttc atttggaagt ccaatagggc aaattgaatg aagtattatt atctgtctct
1741 tgtagtacaa tgtatccaac agacactcaa taaacttttt ggttgtgaaa aaaaaaaaaa
1801 aaaaaaaaaa aaaaaaa
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