LOCUS BC017575 2042 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens CHK1 checkpoint homolog (S. pombe), mRNA (cDNA clone
MGC:24475 IMAGE:4091997), complete cds.
ACCESSION BC017575
VERSION BC017575.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2042)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2042)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 32 Row: j Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20127419.
FEATURES Location/Qualifiers
source 1..2042
/db_xref="H-InvDB:HIT000038059"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:24475 IMAGE:4091997"
/tissue_type="Bone marrow, acute myelogenous leukemia"
/clone_lib="NIH_MGC_55"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..2042
/gene="CHEK1"
/gene_synonym="CHK1"
/db_xref="GeneID:1111"
/db_xref="HGNC:HGNC:1925"
/db_xref="MIM:603078"
CDS 159..1589
/gene="CHEK1"
/gene_synonym="CHK1"
/codon_start=1
/product="CHK1 checkpoint homolog (S. pombe)"
/protein_id="AAH17575.1"
/db_xref="GeneID:1111"
/db_xref="HGNC:HGNC:1925"
/db_xref="MIM:603078"
/translation="MAVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKR
AVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGM
PEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNR
ERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEY
SDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRP
RVTSGGVSESPSGFSKHIQSNLDFSPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSY
IDKLVQGISFSQPTCPDHMLLNSQLLGTPGSSQNPWQRLVKRMTRFFTKLDADKSYQC
LKETCEKLGYQWKKSCMNQVTISTTDRRNNKLIFKVNLLEMDDKILVDFRLSKGDGLE
FKRHFLKIKGKLIDIVSSQKVWLPAT"
BASE COUNT 643 a 382 c 444 g 573 t
ORIGIN
1 ggggccagtc gttcgccgga aagcatttgt ctcccacctc atcataacaa caattaattt
61 cctctggggc ctgaggaggg cagaatttca accttcggtg tgcttgggag tggcgattgt
121 gatttacacg acaaaatgcc gaggtgctcg gtggagtcat ggcagtgccc tttgtggaag
181 actgggactt ggtgcaaacc ctgggagaag gtgcctatgg agaagttcaa cttgctgtga
241 atagagtaac tgaagaagca gtcgcagtga agattgtaga tatgaagcgt gccgtagact
301 gtccagaaaa tattaagaaa gagatctgta tcaataaaat gctaaatcat gaaaatgtag
361 taaaattcta tggtcacagg agagaaggca atatccaata tttatttctg gagtactgta
421 gtggaggaga gctttttgac agaatagagc cagacatagg catgcctgaa ccagatgctc
481 agagattctt ccatcaactc atggcagggg tggtttatct gcatggtatt ggaataactc
541 acagggatat taaaccagaa aatcttctgt tggatgaaag ggataacctc aaaatctcag
601 actttggctt ggcaacagta tttcggtata ataatcgtga gcgtttgttg aacaagatgt
661 gtggtacttt accatatgtt gctccagaac ttctgaagag aagagaattt catgcagaac
721 cagttgatgt ttggtcctgt ggaatagtac ttactgcaat gctcgctgga gaattgccat
781 gggaccaacc cagtgacagc tgtcaggagt attctgactg gaaagaaaaa aaaacatacc
841 tcaacccttg gaaaaaaatc gattctgctc ctctagctct gctgcataaa atcttagttg
901 agaatccatc agcaagaatt accattccag acatcaaaaa agatagatgg tacaacaaac
961 ccctcaagaa aggggcaaaa aggccccgag tcacttcagg tggtgtgtca gagtctccca
1021 gtggattttc taagcacatt caatccaatt tggacttctc tccagtaaac agtgcttcta
1081 gtgaagaaaa tgtgaagtac tccagttctc agccagaacc ccgcacaggt ctttccttat
1141 gggataccag cccctcatac attgataaat tggtacaagg gatcagcttt tcccagccca
1201 catgtcctga tcatatgctt ttgaatagtc agttacttgg caccccagga tcctcacaga
1261 acccctggca gcggttggtc aaaagaatga cacgattctt taccaaattg gatgcagaca
1321 aatcttatca atgcctgaaa gagacttgtg agaagttggg ctatcaatgg aagaaaagtt
1381 gtatgaatca ggttactata tcaacaactg ataggagaaa caataaactc attttcaaag
1441 tgaatttgtt agaaatggat gataaaatat tggttgactt ccggctttct aagggtgatg
1501 gattggagtt caagagacac ttcctgaaga ttaaagggaa gctgattgat attgtgagca
1561 gccagaaggt ttggcttcct gccacatgat cggaccatcg gctctgggga atcctggtga
1621 atatagtgct gctatgttga cattattctt cctagagaag attatcctgt cctgcaaact
1681 gcaaatagta gttcctgaag tgttcacttc cctgtttatc caaacatctt ccaatttatt
1741 ttgtttgttc ggcatacaaa taatacctat atcttaattg taagcaaaac tttggggaaa
1801 ggatgaatag aattcatttg attatttctt catgtgtgtt tagtatctga atttgaaact
1861 catctggtgg aaaccaagtt tcaggggaca tgagttttcc agcttttata cacacgtatc
1921 tcatttttat caaaacattt tgtttaattc aaaaagtaca tatttcttcc atgttgattt
1981 aattctaaga tgaaccaata aagacataat tcttgcaaaa aaaaaaaaaa aaaaaaaaaa
2041 aa
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