LOCUS BC017477 2749 bp mRNA linear HUM 27-APR-2005
DEFINITION Homo sapiens methylenetetrahydrofolate dehydrogenase (NADP+
dependent) 1-like, mRNA (cDNA clone IMAGE:2960864), partial cds.
ACCESSION BC017477
VERSION BC017477.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2749)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2749)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 22 Row: c Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40018634.
FEATURES Location/Qualifiers
source 1..2749
/db_xref="H-InvDB:HIT000038026"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:2960864"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2749
/gene="MTHFD1L"
/gene_synonym="dJ292B18.2"
/gene_synonym="DKFZp586G1517"
/gene_synonym="FLJ21145"
/db_xref="GeneID:25902"
CDS <1..2328
/gene="MTHFD1L"
/gene_synonym="dJ292B18.2"
/gene_synonym="DKFZp586G1517"
/gene_synonym="FLJ21145"
/codon_start=1
/product="MTHFD1L protein"
/protein_id="AAH17477.2"
/db_xref="GeneID:25902"
/translation="AKAVIELLEKSGVNLDGKKILVVGAHGSLEAALQCLFQRKGSMT
MSIQWKTRQLQSKLHEADIVVLGSPKPEEIPLTWIQPGTTVLNCSHDFLSGKVGCGSP
RIHFGGLIEEDDVILLAAALRIQNMVSSGRRWLREQQHRRWRLHCLKLQPLSPVPSDI
EISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVRLSVLERLKDQADGKYVLVAGIT
PTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPME
EFNLHLTGDIHAITAANNLLAAAIDTRILHENTQTDKALYNRLVPLVNGVREFSEIQL
ARLKKLGINKTDPSTLTEEEVSKFARLDIDPSTITWQRVLDTNDRFLRKITIGQGNTE
KGHYRQAQFDIAVASEIMAVLALTDSLADMKARLGRMVVASDKSGQPVTADDLGVTGA
LTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTE
AGFGADIGMEKFFNIKCRASGLVPNVVVLVATVRALKMHGGGPSVTAGVPLKKEYTEE
NIQLVADGCCNLQKQIQITQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFDAVP
CYHWSVGGKGSVDLARAVREAASKRSRFQFLYDVQVPIVDKIRTIAQAVYGAKDIELS
PEAQAKIDRYTQQGFGNLPICMAKTHLSLSHQPDKKGVPRDFILPISDVRASIGAGFI
YPLVGTMSTMPGLPTRPCFYDIDLDTETEQVKGLF"
BASE COUNT 763 a 605 c 715 g 666 t
ORIGIN
1 gccaaagctg taattgaact tcttgaaaaa tcaggtgtca acctagatgg aaagaagatt
61 ttggtagtgg gggcccatgg gtctttggaa gctgctctac aatgcctgtt ccagagaaaa
121 gggtccatga caatgagcat ccagtggaaa acacgccagc ttcaaagcaa gcttcacgag
181 gctgacattg tggtcctagg ctcacctaag ccagaagaga ttccccttac ttggatacaa
241 ccaggaacta ctgttctcaa ctgctcccat gacttcctgt cagggaaggt tgggtgtggc
301 tctccaagaa tacattttgg tggactcatt gaggaagatg atgtgattct ccttgctgca
361 gctctgcgaa ttcagaacat ggtcagtagt ggaaggagat ggcttcgtga acagcagcac
421 aggcggtgga gacttcactg cttgaaactt cagcctctct cccctgtgcc aagtgacatt
481 gagatttcaa gaggacaaac tccaaaagct gtggatgtcc ttgccaagga gattggattg
541 cttgcagatg aaattgaaat ctatggcaaa agcaaagcca aagtacgttt gtccgtgcta
601 gaaaggttaa aggatcaagc agatggaaaa tacgtcttag ttgctgggat cacacccacc
661 cctcttggag aagggaagag cacagtcacc atcgggcttg tgcaggctct gaccgcacac
721 ctgaatgtca actcctttgc ctgcttgagg cagccttccc aaggaccgac gtttggagtg
781 aaaggaggag ccgcgggtgg tggatatgcc caggtcatcc ccatggagga gttcaacctt
841 cacttgactg gagacatcca cgccatcacc gctgccaata acttgctggc tgccgccatc
901 gacacgagga ttcttcatga aaacacgcaa acagataagg ctctgtataa tcggctggtt
961 cctttagtga atggtgtcag agaattttca gaaattcagc ttgctcggct aaaaaaactg
1021 ggaataaata agactgatcc gagcacactg acagaagagg aagtgagtaa atttgcccgt
1081 ctcgacatcg acccatctac catcacgtgg cagagagtat tggatacaaa tgaccgattt
1141 ctacgaaaaa taaccatcgg gcagggaaac acagagaagg gccattaccg gcaggcgcag
1201 tttgacatcg cagtggccag cgagatcatg gcggtgctgg ccctgacgga cagcctcgca
1261 gacatgaagg cacggctggg aaggatggtg gtggccagtg acaaaagcgg gcagcctgtg
1321 acagcagatg atttgggggt gacaggtgct ttgacagttt tgatgaaaga tgcaataaaa
1381 ccaaacctga tgcagaccct ggaagggaca cctgtgttcg tgcatgcggg cccttttgct
1441 aacattgctc acggcaactc ttcagtgttg gctgataaaa ttgccctgaa actggttggt
1501 gaagaaggat ttgtagtgac cgaagctggc tttggtgctg acatcggaat ggagaaattc
1561 ttcaacatca agtgccgagc ttccggcttg gtgcccaacg tggttgtgtt agtggcaacg
1621 gtgcgagctc tgaagatgca tggaggcggg ccaagtgtaa cggctggtgt tcctcttaag
1681 aaagaatata cagaggagaa catccagctg gtggcagacg gctgctgtaa cctccagaag
1741 caaattcaga tcactcagct ctttggggtt cccgttgtgg tggctctgaa tgtcttcaag
1801 accgacaccc gcgctgagat tgacttggtg tgtgagcttg caaagcgggc tggtgccttt
1861 gatgcagtcc cctgctatca ctggtcggtt ggtggaaaag gatcggtgga cttggctcgg
1921 gctgtgagag aggctgcgag taaaagaagc cgattccagt tcctgtatga tgttcaggtt
1981 ccaattgtgg acaagataag gaccattgct caggctgtct atggagccaa agatattgaa
2041 ctctctcctg aggcacaagc caaaatagat cgttacactc aacagggttt tggaaatttg
2101 cccatctgca tggcaaagac ccacctttct ctatctcacc aacctgacaa aaaaggtgtg
2161 ccaagggact tcatcttacc tatcagtgac gtccgggcca gcataggcgc tgggttcatt
2221 taccctttgg tcggaacgat gagcaccatg ccaggactgc ccacccggcc ctgcttttat
2281 gacatagatc ttgataccga aacagaacaa gttaaaggct tgttctaagt ggacaaggct
2341 ctcacaggac ccgatgcaga ctcctgaaac agactactct ttgccttttt gctgcagttg
2401 gagaagaaac tgaatttgaa aaatgtctgt tatgcaatgc tggagacgtg gtgaaatagg
2461 ccaaagattt cttcttcgtt caagatgaat tctgttcaca gtggagtatg gtgttcggca
2521 aaaggacctc caccaagact gaaagaaact aatttatttc tgtttctgtg gagtttccat
2581 tatttctact gcttacactt tagaatgttt attttatggg gactaaggga ttaggagtgt
2641 gaactaaaag gtaacatttt ccactctcaa gttttctact ttgtctttga actgaaaata
2701 aacatggatc tagaaaccca aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//