LOCUS BC017378 1824 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens hexosaminidase B (beta polypeptide), mRNA (cDNA clone
MGC:1725 IMAGE:2967035), complete cds.
ACCESSION BC017378
VERSION BC017378.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1824)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1824)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC017378.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 3 Row: e Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13128866.
FEATURES Location/Qualifiers
source 1..1824
/db_xref="H-InvDB:HIT000037979"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1725 IMAGE:2967035"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1824
/gene="HEXB"
/gene_synonym="ENC-1AS"
/db_xref="GeneID:3074"
/db_xref="HGNC:HGNC:4879"
/db_xref="MIM:606873"
CDS 23..1693
/gene="HEXB"
/gene_synonym="ENC-1AS"
/codon_start=1
/product="hexosaminidase B (beta polypeptide)"
/protein_id="AAH17378.1"
/db_xref="GeneID:3074"
/db_xref="HGNC:HGNC:4879"
/db_xref="MIM:606873"
/translation="MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEAAR
APSVSAKPGPALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYH
GYIFGFYKWHHEPAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVL
KANRVWGALRGLETFSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKI
ILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIE
YARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLT
TFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMRQKGFGTDFKKLESFYIQKVL
DIIATINKGSIVWQEVFDDKAKLAPGTIVEVWKDSAYPEELSRVTASGFPVILSAPWY
LDLISYGQDWRKYYKVEPLDFGGTQKQKQLFIGGEACLWGEYVDATNLTPRLWPRASA
VGERLWSSKDVRDMDDAYDRLTRHRCRMVERGIAAQPLYAGYCNHENM"
BASE COUNT 515 a 387 c 425 g 497 t
ORIGIN
1 ggcggaaagc agccgagcgg ccatggagct gtgcgggctg gggctgcccc ggccgcccat
61 gctgctggcg ctgctgttgg cgacactgct ggcggcgatg ttggcgctgc tgactcaggt
121 ggcgctggtg gtgcaggtgg cggaggcggc tcgggccccg agcgtctcgg ccaagccggg
181 gccggcgctg tggcccctgc cgctctcggt gaagatgacc ccgaacctgc tgcatctcgc
241 cccggagaac ttctacatca gccacagccc caattccacg gcgggcccct cctgcaccct
301 gctggaggaa gcgtttcgac gatatcatgg ctatattttt ggtttctaca agtggcatca
361 tgaacctgct gaattccagg ctaaaaccca ggttcagcaa cttcttgtct caatcaccct
421 tcagtcagag tgtgatgctt tccccaacat atcttcagat gagtcttata ctttacttgt
481 gaaagaacca gtggctgtcc ttaaggccaa cagagtttgg ggagcattac gaggtttaga
541 gacctttagc cagttagttt atcaagattc ttatggaact ttcaccatca atgaatccac
601 cattattgat tctccaaggt tttctcacag aggaattttg attgatacat ccagacatta
661 tctgccagtt aagattattc ttaaaactct ggatgccatg gcttttaata agtttaatgt
721 tcttcactgg cacatagttg atgaccagtc tttcccatat cagagcatca cttttcctga
781 gttaagcaat aaaggaagct attctttgtc tcatgtttat acaccaaatg atgtccgtat
841 ggtgattgaa tatgccagat tacgaggaat tcgagtcctg ccagaatttg atacccctgg
901 gcatacacta tcttggggaa aaggtcagaa agacctcctg actccatgtt acagtagaca
961 aaacaagttg gactcttttg gacctataaa ccctactctg aatacaacat acagcttcct
1021 tactacattt ttcaaagaaa ttagtgaggt gtttccagat caattcattc atttgggagg
1081 agatgaagtg gaatttaaat gttgggaatc aaatccaaaa attcaagatt tcatgaggca
1141 aaaaggcttt ggcacagatt ttaagaaact agaatctttc tacattcaaa aggttttgga
1201 tattattgca accataaaca agggatccat tgtctggcag gaggtttttg atgataaagc
1261 aaagcttgcg ccgggcacaa tagttgaagt atggaaagac agcgcatatc ctgaggaact
1321 cagtagagtc acagcatctg gcttccctgt aatcctttct gctccttggt acttagattt
1381 gattagctat ggacaagatt ggaggaaata ctataaagtg gaacctcttg attttggcgg
1441 tactcagaaa cagaaacaac ttttcattgg tggagaagct tgtctatggg gagaatatgt
1501 ggatgcaact aacctcactc caagattatg gcctcgggca agtgctgttg gtgagagact
1561 ctggagttcc aaagatgtca gagatatgga tgacgcctat gacagactga caaggcaccg
1621 ctgcaggatg gtcgaacgtg gaatagctgc acaacctctt tatgctggat attgtaacca
1681 tgagaacatg taaaaaatgg aggggaaaaa ggccacagca atctgtacta caatcaactt
1741 tattttgaaa tcatgtaaaa taagatatta gactgttttt tgaataaaat atttttattg
1801 attgaaaaaa aaaaaaaaaa aaaa
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