LOCUS BC017310 1438 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens sepiapterin reductase (7,8-dihydrobiopterin:NADP+
oxidoreductase), mRNA (cDNA clone MGC:29567 IMAGE:5089862),
complete cds.
ACCESSION BC017310
VERSION BC017310.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1438)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1438)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC017310.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: o Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 52851434.
FEATURES Location/Qualifiers
source 1..1438
/db_xref="H-InvDB:HIT000037938"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29567 IMAGE:5089862"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_42"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1438
/gene="SPR"
/db_xref="GeneID:6697"
/db_xref="HGNC:HGNC:11257"
/db_xref="MIM:182125"
CDS 15..800
/gene="SPR"
/codon_start=1
/product="sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase)"
/protein_id="AAH17310.1"
/db_xref="GeneID:6697"
/db_xref="HGNC:HGNC:11257"
/db_xref="MIM:182125"
/translation="MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARND
EALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAG
SLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCA
LQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDM
RKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK"
BASE COUNT 306 a 401 c 433 g 298 t
ORIGIN
1 cggagaacag gagcatggag ggcgggctgg ggcgtgctgt gtgcttgctg accggggcct
61 cccgcggctt cggccggacg ctggccccgc tcctggcctc gctgctgtcg cccggctccg
121 tgcttgtcct tagcgcccgc aacgacgagg cactgcgcca gctggaggcc gagctgggcg
181 ccgagcggtc tggcctgcgc gtggtgcggg tgcccgccga cctgggcgcc gaggccggct
241 tgcagcagct gctcggcgcc ctgcgcgagc tcccccggcc caaggggctg cagcgactgc
301 tgcttatcaa caacgcgggc tctcttgggg atgtgtccaa aggcttcgtg gacctgagtg
361 actccactca agtgaacaac tactgggcac tgaacttgac ctccatgctc tgcctgactt
421 ccagcgtcct gaaggccttc ccggacagtc ctggcctcaa cagaaccgtg gttaacatct
481 cgtccctctg tgccctgcaa cctttcaaag gctgggcgct gtactgtgca ggaaaggctg
541 ctcgtgatat gctgttccag gtcctggcgc tggaggaacc taatgtgagg gtgctgaact
601 atgccccagg tcctctggac acagacatgc agcagttggc ccgggagacc tccgtggacc
661 cagacatgcg aaaagggctg caggagctga aggcaaaggg gaagctggtg gattgcaagg
721 tgtcagccca gaaactgctg agcttactgg aaaaggacga gttcaagtct ggagcccacg
781 tggacttcta tgacaaataa gcccatgttt ttggcttcct gaaccttttt gcccccactt
841 ttagacatac cccagagccc tgtggctccc cacaccctgc cataggggca gtcctgcctt
901 acacatagaa gcattcatgc ctgctgccct gccctcaggc acagccagct gtgagctccc
961 aggtcattgg ccttaccagt tgtcaggagt ctgtgctgtg caccctgggt tataaggagg
1021 cttaggagag aggttatggg tattggtgtc tctatcccca ggaatagaac ttaaggggtg
1081 ggaagaacag gaaaagaagc tggaacacag aagagaggag gttgtgtctc ttgctcatag
1141 caagcctgtg ggtagaggaa agagtgatct ggtgtcgaat aggaggaccc atgtagattc
1201 gcagatggcc tggatgggag gaagggcaga cggtacatgt cccagcccac atagatgccc
1261 cttgctgagg gtagcaggac cttctgttga actttgtgtc ctcactctga tgtctccttc
1321 cttcagaatc taccacccct cccccaggct gggagaaggg gctcctgggt gtctgtatac
1381 acgccaaagg cagatacaaa taaaatacag attgtccttt aaaaaaaaaa aaaaaaaa
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