LOCUS BC017304 2718 bp mRNA linear HUM 13-SEP-2007
DEFINITION Homo sapiens nuclear receptor subfamily 1, group I, member 2, mRNA
(cDNA clone MGC:29598 IMAGE:5087401), complete cds.
ACCESSION BC017304
VERSION BC017304.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2718)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2718)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC017304.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CGAP (Stanford)
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 39 Row: o Column: 4.
FEATURES Location/Qualifiers
source 1..2718
/db_xref="H-InvDB:HIT000037932"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:29598 IMAGE:5087401"
/tissue_type="Liver, hepatocellular carcinoma"
/clone_lib="NIH_MGC_100"
/lab_host="DH10B"
/note="Vector: pOTB7"
gene 1..2718
/gene="NR1I2"
/gene_synonym="BXR"
/gene_synonym="ONR1"
/gene_synonym="PAR"
/gene_synonym="PAR1"
/gene_synonym="PAR2"
/gene_synonym="PARq"
/gene_synonym="PRR"
/gene_synonym="PXR"
/gene_synonym="SAR"
/gene_synonym="SXR"
/db_xref="GeneID:8856"
/db_xref="HGNC:HGNC:7968"
/db_xref="MIM:603065"
CDS 240..1541
/gene="NR1I2"
/gene_synonym="BXR"
/gene_synonym="ONR1"
/gene_synonym="PAR"
/gene_synonym="PAR1"
/gene_synonym="PAR2"
/gene_synonym="PARq"
/gene_synonym="PRR"
/gene_synonym="PXR"
/gene_synonym="SAR"
/gene_synonym="SXR"
/note="alternative start codon"
/codon_start=1
/product="NR1I2 protein"
/protein_id="AAH17304.2"
/db_xref="GeneID:8856"
/db_xref="HGNC:HGNC:7968"
/db_xref="MIM:603065"
/translation="MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVC
GDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKC
LESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK
TFDTTFSHFKNFRPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGED
GSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLK
GAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQL
HEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKI
MAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS"
BASE COUNT 680 a 704 c 748 g 586 t
ORIGIN
1 ggaagaggaa gcactgcctt tacttcagtg ggaatctcgg cctcagcctg caagccaagt
61 gttcacagtg agaaaagcaa gagaataagc taatactcct gtcctgaaaa aggcagcggc
121 tccttggtaa agctactcct tgatcgatcc tttgcaccgg attgttcaaa gtggacccca
181 ggggagaagt cggagcaaag aacttaccac caagcagtcc aagaggccca gaagcaaacc
241 tggaggtgag acccaaagaa agctggaacc atgctgactt tgtacactgt gaggacacag
301 agtctgttcc tggaaagccc agtgtcaacg cagatgagga agtcggaggt ccccaaatct
361 gccgtgtatg tggggacaag gccactggct atcacttcaa tgtcatgaca tgtgaaggat
421 gcaagggctt tttcaggagg gccatgaaac gcaacgcccg gctgaggtgc cccttccgga
481 agggcgcctg cgagatcacc cggaagaccc ggcgacagtg ccaggcctgc cgcctgcgca
541 agtgcctgga gagcggcatg aagaaggaga tgatcatgtc cgacgaggcc gtggaggaga
601 ggcgggcctt gatcaagcgg aagaaaagtg aacggacagg gactcagcca ctgggagtgc
661 aggggctgac agaggagcag cggatgatga tcagggagct gatggacgct cagatgaaaa
721 cctttgacac taccttctcc catttcaaga atttccggcc aggggtgctt agcagtggct
781 gcgagttgcc agagtctctg caggccccat cgagggaaga agctgccaag tggagccagg
841 tccggaaaga tctgtgctct ttgaaggtct ctctgcagct gcggggggag gatggcagtg
901 tctggaacta caaaccccca gccgacagtg gcgggaaaga gatcttctcc ctgctgcccc
961 acatggctga catgtcaacc tacatgttca aaggcatcat cagctttgcc aaagtcatct
1021 cctacttcag ggacttgccc atcgaggacc agatctccct gctgaagggg gccgctttcg
1081 agctgtgtca actgagattc aacacagtgt tcaacgcgga gactggaacc tgggagtgtg
1141 gccggctgtc ctactgcttg gaagacactg caggtggctt ccagcaactt ctactggagc
1201 ccatgctgaa attccactac atgctgaaga agctgcagct gcatgaggag gagtatgtgc
1261 tgatgcaggc catctccctc ttctccccag accgcccagg tgtgctgcag caccgcgtgg
1321 tggaccagct gcaggagcaa ttcgccatta ctctgaagtc ctacattgaa tgcaatcggc
1381 cccagcctgc tcataggttc ttgttcctga agatcatggc tatgctcacc gagctccgca
1441 gcatcaatgc tcagcacacc cagcggctgc tgcgcatcca ggacatacac ccctttgcta
1501 cgcccctcat gcaggagttg ttcggcatca caggtagctg agcggctgcc cttgggtgac
1561 acctccgaga ggcagccaga cccagagccc tctgagccgc cactcccggg ccaagacaga
1621 tggacactgc caagagccga caatgccctg ctggcctgtc tccctaggga attcctgcta
1681 tgacagctgg ctagcattcc tcaggaagga catgggtgcc ccccaccccc agttcagtct
1741 gtagggagtg aagccacaga ctcttacgtg gagagtgcac tgacctgtag gtcaggacca
1801 tcagagaggc aaggttgccc tttcctttta aaaggccctg tggtctgggg agaaatccct
1861 cagatcccac taaagtgtca aggtgtggaa gggaccaagc gaccaaggat gggccatctg
1921 gggtctatgc ccacataccc acgtttgttc gcttcctgag tcttttcatt gctacctcta
1981 atagtcctgt ctcccacttc ccactcgttc ccctcctctt ccgagctgct ttgtgggctc
2041 caggcctgta ctcatcggca ggcgcatgag tatctgtggg agtcctctag agagatgaga
2101 agccaggagg cctgcaccaa atgtcagaag cttggcatga cctcattccg gccacatcat
2161 tctgtgtctc tgcatccatt tgaacacatt attaagcacc gataataggt agcctgctgt
2221 ggggtataca gcattgactc agatatagat cctgagctca cagagtttat agttaaaaaa
2281 acaaacagaa acacaaacaa tttggatcaa aaggagaaat gataagtgac aaaagcagca
2341 caaggaattt ccctgtgtgg atgctgagct gtgatggcgg gcactgggta cccaagtgaa
2401 ggttcccgag gacatgagtc tgtaggagca agggcacaaa ctgcagctgt gagtgcgtgt
2461 gtgtgatttg gtgtaggtag gtctgtttgc cacttgatgg ggcctgggtt tgttcctggg
2521 gctggaatgc tgggtatgct ctgtgacaag gctacgctga caatcagtta aacacaccgg
2581 agaagaacca tttacatgca ccttatattt ctgtgtacac atctattctc aaagctaaag
2641 ggtatgaaag tgcctgcctt gtttatagcc acttgtgagt aaaaattttt ttgcattttc
2701 aaaaaaaaaa aaaaaaaa
//