LOCUS BC017222 2870 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens sequestosome 1, mRNA (cDNA clone MGC:14328
IMAGE:4298142), complete cds.
ACCESSION BC017222
VERSION BC017222.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2870)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2870)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 20 Row: k Column: 1.
FEATURES Location/Qualifiers
source 1..2870
/db_xref="H-InvDB:HIT000037887"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14328 IMAGE:4298142"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_46"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2870
/gene="SQSTM1"
/gene_synonym="p60"
/gene_synonym="p62"
/gene_synonym="ZIP3"
/db_xref="GeneID:8878"
/db_xref="HGNC:HGNC:11280"
/db_xref="MIM:601530"
CDS 41..1363
/gene="SQSTM1"
/gene_synonym="p60"
/gene_synonym="p62"
/gene_synonym="ZIP3"
/codon_start=1
/product="sequestosome 1"
/protein_id="AAH17222.1"
/db_xref="GeneID:8878"
/db_xref="HGNC:HGNC:11280"
/db_xref="MIM:601530"
/translation="MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPC
ERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEK
KECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLH
RGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARP
GPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESS
STEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGG
DDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADP
RLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL"
BASE COUNT 607 a 803 c 822 g 638 t
ORIGIN
1 ggcctgggtg gcgaattcgg cacgaggctc gccgctcgct atggcgtcgc tcaccgtgaa
61 ggcctacctt ctgggcaagg aggacgcggc gcgcgagatt cgccgcttca gcttctgctg
121 cagccccgag cctgaggcgg aagccgaggc tgcggcgggt ccgggaccct gcgagcggct
181 gctgagccgg gtggccgccc tgttccccgc gctgcggcct ggcggcttcc aggcgcacta
241 ccgcgatgag gacggggact tggttgcctt ttccagtgac gaggaattga caatggccat
301 gtcctacgtg aaggatgaca tcttccgaat ctacattaaa gagaaaaaag agtgccggcg
361 ggaccaccgc ccaccgtgtg ctcaggaggc gccccgcaac atggtgcacc ccaatgtgat
421 ctgcgatggc tgcaatgggc ctgtggtagg aacccgctac aagtgcagcg tctgcccaga
481 ctacgacttg tgtagcgtct gcgagggaaa gggcttgcac cgggggcaca ccaagctcgc
541 attccccagc cccttcgggc acctgtctga gggcttctcg cacagccgct ggctccggaa
601 ggtgaaacac ggacacttcg ggtggccagg atgggaaatg ggtccaccag gaaactggag
661 cccacgtcct cctcgtgcag gggaggcccg ccctggcccc acggcagaat cagcttctgg
721 tccatcggag gatccgagtg tgaatttcct gaagaacgtt ggggagagtg tggcagctgc
781 ccttagccct ctgggcattg aagttgatat cgatgtggag cacggaggga aaagaagccg
841 cctgaccccc gtctctccag agagttccag cacagaggag aagagcagct cacagccaag
901 cagctgctgc tctgatccca gcaagccggg tgggaatgtt gagggcgcca cgcagtctct
961 ggcggagcag atgagaaaga tcgccttgga gtccgagggg cgccctgagg aacagatgga
1021 gtcggataac tgttcaggag gagatgatga ctggacccat ctgtcttcaa aagaagtgga
1081 cccgtctaca ggtgaactcc agtccctaca gatgccagaa tccgaagggc caagctctct
1141 ggacccctcc caggagggac ccacagggct gaaggaagct gccttgtacc cacatctccc
1201 gccagaggct gacccgcggc tgattgagtc cctctcccag atgctgtcca tgggcttctc
1261 tgatgaaggc ggctggctca ccaggctcct gcagaccaag aactatgaca tcggagcggc
1321 tctggacacc atccagtatt caaagcatcc cccgccgttg tgaccacttt tgcccacctc
1381 ttctgcgtgc ccctcttctg tctcatagtt gtgttaagct tgcgtagaat tgcaggtctc
1441 tgtacaggcc agtttctctg ccttcttcca ggatcagggg ttagggtgca agaagccatt
1501 tagggcagca aaacaagtga catgaaggga gggtccctgt gtgtgtgtgt gtgctgatgt
1561 ttcctgggtg ccctggctcc ttgcagcagg gctgggcctg cgagacccaa ggctcactgc
1621 agcgcgctcc tgacccctcc ctgcaggggc tacgttagca gcccagcaca tagcttgcct
1681 aatggctttc actttctctt ttgttttaaa tgactcatag gtccctgaca tttagttgat
1741 tattttctgc tacagacctg gtacactctg attttagata aagtaagcct aggtgttgtc
1801 agcaggcagg ctggggaggc cagtgttgtg ggcttcctgc tgggactgag aaggctcacg
1861 aagggcatcc gcaatgttgg tttcactgag agctgcctcc tggtctcttc accactgtag
1921 ttctctcatt tccaaaccat cagctgcttt taaaataaga tctctttgta gccatcctgt
1981 taaatttgta aacaatctaa ttaaatggca tcagcacttt aaccaatgac gtttgcatag
2041 agagaaatga ttgacagtaa gtttattgtt aatggttctt acagagtatc tttaaaagtg
2101 ccttagggga accctgtccc tcctaacaag tgtatctcga ttaataacct gccagtccca
2161 gatcacacat catcatcgaa gtcttcccca gttataaaga ggtcacatag tcgtgtgggt
2221 cgaggattct gtgcctccag gaccaggggc ccaccctctg cccagggagt ccttgcgtcc
2281 catgaggtct tcccgcaagg cctctcagac ccagatgtga cggggtgtgt ggcccgagga
2341 agctggacag cggcagtggg cctgctgagg ccttctcttg aggcctgtgc tctgggggtc
2401 ccttgcttag cctgtgctgg accagctggc ctggggtccc tctgaagaga ccttggctgc
2461 tcactgtcca catgtgaact ttttctaggt ggcaggacaa atcgcgccca tttagaggat
2521 gtggctgtaa cctgctggat gggactccat agctccttcc caggacccct cagctccccg
2581 gcactgcagt ctgcagagtt ctcctggagg caggggctgc tgccttgttt caccttccat
2641 gtcaggccag cctgtccctg aaagagaaga tggccatgcc ctccatttgt aagaacaatg
2701 ccagggccca ggaggaccgc ctgccctgcc tgggccttgg ctgggcctct ggttctgaca
2761 ctttctgctg gaagctgtca ggctgggaca ggctttgatt ttgagggtta gcaagacaaa
2821 gcaaataaat gccttccacc tcaccgcaaa aaaaaaaaaa aaaaaaaaaa
//