LOCUS BC017197 3944 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens myeloid cell leukemia sequence 1 (BCL2-related), mRNA
(cDNA clone MGC:1839 IMAGE:3138465), complete cds.
ACCESSION BC017197
VERSION BC017197.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3944)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3944)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC017197.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: p Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33519457.
FEATURES Location/Qualifiers
source 1..3944
/db_xref="H-InvDB:HIT000037867"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1839 IMAGE:3138465"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3944
/gene="MCL1"
/gene_synonym="EAT"
/gene_synonym="MCL1L"
/gene_synonym="MCL1S"
/gene_synonym="MGC1839"
/gene_synonym="TM"
/db_xref="GeneID:4170"
/db_xref="HGNC:HGNC:6943"
/db_xref="MIM:159552"
CDS 55..1107
/gene="MCL1"
/gene_synonym="EAT"
/gene_synonym="MCL1L"
/gene_synonym="MCL1S"
/gene_synonym="MGC1839"
/gene_synonym="TM"
/codon_start=1
/product="myeloid cell leukemia sequence 1 (BCL2-related)"
/protein_id="AAH17197.1"
/db_xref="GeneID:4170"
/db_xref="HGNC:HGNC:6943"
/db_xref="MIM:159552"
/translation="MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASA
RREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPT
RRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSL
PSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGD
GVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAK
HLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLA
FAGVAGVGAGLAYLIR"
BASE COUNT 1050 a 802 c 968 g 1124 t
ORIGIN
1 aaggagtcgg ggtcttcccc agttttctca gccaggcggc ggcggcgact ggcaatgttt
61 ggcctcaaaa gaaacgcggt aatcggactc aacctctact gtgggggggc cggcttgggg
121 gccggcagcg gcggcgccac ccgcccggga gggcgacttt tggctacgga gaaggaggcc
181 tcggcccggc gagagatagg gggaggggag gccggcgcgg tgattggcgg aagcgccggc
241 gcaagccccc cgtccaccct cacgccagac tcccggaggg tcgcgcggcc gccgcccatt
301 ggcgccgagg tccccgacgt caccgcgacc cccgcgaggc tgcttttctt cgcgcccacc
361 cgccgcgcgg cgccgcttga ggagatggaa gccccggccg ctgacgccat catgtcgccc
421 gaagaggagc tggacgggta cgagccggag cctctcggga agcggccggc tgtcctgccg
481 ctgctggagt tggtcgggga atctggtaat aacaccagta cggacgggtc actaccctcg
541 acgccgccgc cagcagagga ggaggaggac gagttgtacc ggcagtcgct ggagattatc
601 tctcggtacc ttcgggagca ggccaccggc gccaaggaca caaagccaat gggcaggtct
661 ggggccacca gcaggaaggc gctggagacc ttacgacggg ttggggatgg cgtgcagcgc
721 aaccacgaga cggccttcca aggcatgctt cggaaactgg acatcaaaaa cgaagacgat
781 gtgaaatcgt tgtctcgagt gatgatccat gttttcagcg acggcgtaac aaactggggc
841 aggattgtga ctctcatttc ttttggtgcc tttgtggcta aacacttgaa gaccataaac
901 caagaaagct gcatcgaacc attagcagaa agtatcacag acgttctcgt aaggacaaaa
961 cgggactggc tagttaaaca aagaggctgg gatgggtttg tggagttctt ccatgtagag
1021 gacctagaag gtggcatcag gaatgtgctg ctggcttttg caggtgttgc tggagtagga
1081 gctggtttgg catatctaat aagatagcct tactgtaagt gcaatagttg acttttaacc
1141 aaccaccacc accaccaaaa ccagtttatg cagttggact ccaagctgta acttcctaga
1201 gttgcaccct agcaacctag ccagaaaagc aagtggcaag aggattatgg ctaacaagaa
1261 taaatacatg ggaagagtgc tccccattga ttgaagagtc actgtctgaa agaagcaaag
1321 ttcagtttca gcaacaaaca aactttgttt gggaagctat ggaggaggac ttttagattt
1381 agtgaagatg gtagggtgga aagacttaat ttccttgttg agaacaggaa agtggccagt
1441 agccaggcaa gtcatagaat tgattacccg ccgaattcat taatttactg tagtgttaag
1501 agaagcacta agaatgccag tgacctgtgt aaaagttaca agtaatagaa ctatgactgt
1561 aagcctcagt actgtacaag ggaagctttt cctctctcta attagctttc ccagtatact
1621 tcttagaaag tccaagtgtt caggactttt atacctgtta tactttggct tggtttccat
1681 gattcttact ttattagcct agtttatcac caataatact tgacggaagg ctcagtaatt
1741 agttatgaat atggatatcc tcaattctta agacagcttg taaatgtatt tgtaaaaatt
1801 gtatatattt ttacagaaag tctatttctt tgaaacgaag gaagtatcga atttacatta
1861 gtttttttca tacccttttg aactttgcaa cttccgtaat taggaacctg tttcttacag
1921 cttttctatg ctaaactttg ttctgttcag ttctagagtg tatacagaac gaattgatgt
1981 gtaactgtat gcagactggt tgtagtggaa caaatctgat aactatgcag gtttaaattt
2041 tcttatctga ttttggtaag tattccttag ataggttttt ctttgaaaac ctgggattga
2101 gaggttgatg aatggaaatt ctttcacttc attatatgca agttttcaat aattaggtct
2161 aagtggagtt ttaaggttac tgatgactta caaataatgg gctctgattg ggcaatactc
2221 atttgagttc cttccatttg acctaattta actggtgaaa tttaaagtga attcatgggc
2281 tcatctttaa agcttttact aaaagatttt cagctgaatg gaactcatta gctgtgtgca
2341 tataaaaaga tcacatcagg tggatggaga gacatttgat cccttgtttg cttaataaat
2401 tataaaatga tggcttggaa aagcaggcta gtctaaccat ggtgctatta ttaggcttgc
2461 ttgttacaca cacaggtcta agcctagtat gtcaataaag caaatactta ctgttttgtt
2521 tctattaatg attcccaaac cttgttgcaa gtttttgcat tggcatcttt ggatttcagt
2581 cttgatgttt gttctatcag acttaacctt ttatttcctg tccttccttg aaattgctga
2641 ttgttctgct ccctctacag atatttatat caattcctac agctttcccc tgccatccct
2701 gaactctttc tagccctttt agattttggc actgtgaaac ccctgctgga aacctgagtg
2761 accctccctc cccaccaaga gtccacagac ctttcatctt tcacgaactt gatcctgtta
2821 gcaggtggta ataccatggg tgctgtgaca ctaacagtca ttgagaggtg ggaggaagtc
2881 ccttttcctt ggactggtat cttttcaact attgttttat cctgtctttg ggggcaatgt
2941 gtcaaaagtc ccctcaggaa ttttcagagg aaagaacatt ttatgaggct ttctctaaag
3001 tttcctttgt ataggagtat gctcacttaa atttacagaa agaggtgagc tgtgttaaac
3061 ctcagagttt aaaagctact gataaactga agaaagtgtc tatattggaa ctagggtcat
3121 ttgaaagctt cagtctcgga acatgacctt tagtctgtgg actccattta aaaataggta
3181 tgaataagat gactaagaat gtaatgggga agaactgccc tgcctgccca tctcagagcc
3241 ataaggtcat ctttgctaga gctattttta cctatgtatt tatcgttctt gatcataagc
3301 cgcttattta tatcatgtat ctctaaggac ctaaaagcac tttatgtagt ttttaattaa
3361 tcttaagatc tggttacggt aactaaaaaa gcctgtctgc caaatccagt ggaaacaagt
3421 gcatagatgt gaattggttt ttaggggccc cacttcccaa ttcattaggt atgactgtgg
3481 aaatacagac aaggatctta gttgatattt tgggcttggg gcagtgaggg cttaggacac
3541 cccaagtggt ttgggaaagg aggaggggag tggtgggttt atagggggag gaggaggcag
3601 gtggtctaag tgctgactgg ctacgtagtt tgggcaaatc ctccaaaagg gaaagggagg
3661 atttgcttag aaggatggcg ctcccagtga ctactttttg acttctgttt gtcttacgct
3721 tctctcaggg aaaaacatgc agtcctctag tgtttcatgt acattctgtg gggggtgaac
3781 accttggttc tggttaaaca gctgtacttt tgatagctgt gccaggaagg gttaggacca
3841 actacaaatt aatgttggtt gtcaaatgta gtgtgtttcc ctaactttct gtttttcctg
3901 agaaaaaaaa ataaatcttt tattcaaaaa aaaaaaaaaa aaaa
//