LOCUS BC016824 1330 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens nucleophosmin (nucleolar phosphoprotein B23,
numatrin), mRNA (cDNA clone MGC:24544 IMAGE:4106286), complete cds.
ACCESSION BC016824
VERSION BC016824.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1330)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1330)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 32 Row: d Column: 5.
FEATURES Location/Qualifiers
source 1..1330
/db_xref="H-InvDB:HIT000037703"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:24544 IMAGE:4106286"
/tissue_type="Bone marrow, acute myelogenous leukemia"
/clone_lib="NIH_MGC_55"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1330
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
CDS 100..984
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/codon_start=1
/product="nucleophosmin (nucleolar phosphoprotein B23,
numatrin)"
/protein_id="AAH16824.1"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
/translation="MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSL
RTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRL
KCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAA
DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSS
TPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCF
RMTDQEAIQDLWQWRKSL"
BASE COUNT 449 a 223 c 318 g 340 t
ORIGIN
1 ggggcctggt gtgattccgt cctgcgcggt tgttctctgg agcagcgttc ttttatctcc
61 gtccgccttc tctcctacct aagtgcgtgc cgccacccga tggaagattc gatggacatg
121 gacatgagcc ccctgaggcc ccagaactat cttttcggtt gtgaactaaa ggccgacaaa
181 gattatcact ttaaggtgga taatgatgaa aatgagcacc agttatcttt aagaacggtc
241 agtttagggg ctggtgcaaa ggatgagttg cacattgttg aagcagaggc aatgaattac
301 gaaggcagtc caattaaagt aacactggca actttgaaaa tgtctgtaca gccaacggtt
361 tcccttgggg gctttgaaat aacaccacca gtggtcttaa ggttgaagtg tggttcaggg
421 ccagtgcata ttagtggaca gcacttagta gctgtggagg aagatgcaga gtcagaagat
481 gaagaggagg aggatgtgaa actcttaagt atatctggaa agcggtctgc ccctggaggt
541 ggtagcaagg ttccacagaa aaaagtaaaa cttgctgctg atgaagatga tgacgatgat
601 gatgaagagg atgatgatga agatgatgat gatgatgatt ttgatgatga ggaagctgaa
661 gaaaaagcgc cagtgaagaa atctatacga gatactccag ccaaaaatgc acaaaagtca
721 aatcagaatg gaaaagactc aaaaccatca tcaacaccaa gatcaaaagg acaagaatcc
781 ttcaagaaac aggaaaaaac tcctaaaaca ccaaaaggac ctagttctgt agaagacatt
841 aaagcaaaaa tgcaagcaag tatagaaaaa ggtggttctc ttcccaaagt ggaagccaaa
901 ttcatcaatt atgtgaagaa ttgcttccgg atgactgacc aagaggctat tcaagatctc
961 tggcagtgga ggaagtctct ttaagaaaat agtttaaaca atttgttaaa aaattttccg
1021 tcttatttca tttctgtaac agttgatatc tggctgtcct ttttataatg cagagtgaga
1081 actttcccta ccgtgtttga taaatgttgt ccaggttgta ttgccaagaa tgtgttgtcc
1141 aaaatgcctg tttagttttt aaagatggaa ctccaccctt tgcttggttt taagtatgta
1201 tggaatgtta tgataggaca tagtagtagc ggtggtcaga catggaaatg gtggggagac
1261 aaaaatatac atgtgaaata aaactcagta ttttaataaa gtgaaaaaaa aaaaaaaaaa
1321 aaaaaaaaaa
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