LOCUS BC016367 1495 bp mRNA linear HUM 02-DEC-2006
DEFINITION Homo sapiens hydroxysteroid (17-beta) dehydrogenase 11, mRNA (cDNA
clone MGC:24582 IMAGE:4133318), complete cds.
ACCESSION BC016367
VERSION BC016367.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1495)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1495)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 32 Row: a Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56786142.
FEATURES Location/Qualifiers
source 1..1495
/db_xref="H-InvDB:HIT000037555"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:24582 IMAGE:4133318"
/tissue_type="Bone marrow, chronic myelogenous leukemia"
/clone_lib="NIH_MGC_54"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1495
/gene="HSD17B11"
/gene_synonym="DHRS8"
/gene_synonym="PAN1B"
/gene_synonym="RETSDR2"
/db_xref="GeneID:51170"
/db_xref="HGNC:HGNC:22960"
CDS 131..1033
/gene="HSD17B11"
/gene_synonym="DHRS8"
/gene_synonym="PAN1B"
/gene_synonym="RETSDR2"
/codon_start=1
/product="hydroxysteroid (17-beta) dehydrogenase 11"
/protein_id="AAH16367.1"
/db_xref="GeneID:51170"
/db_xref="HGNC:HGNC:22960"
/translation="MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGA
GHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYS
SAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT
KNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCP
NFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPER
FLAVLKRKISVKFDAVIGYKMKAQ"
BASE COUNT 473 a 274 c 290 g 458 t
ORIGIN
1 ggggatacgg gagttcctcc ttgctctcgc ccctactctt tctggtgtta gatcgagcta
61 ccctctaaaa gcagtttaga gtggtaaaaa aaaaaaaaaa acacaccaaa cgctcgcagc
121 cacaaaaggg atgaaatttc ttctggacat cctcctgctt ctcccgttac tgatcgtctg
181 ctccctagag tccttcgtga agctttttat tcctaagagg agaaaatcag tcaccggcga
241 aatcgtgctg attacaggag ctgggcatgg aattgggaga ctgactgcct atgaatttgc
301 taaacttaaa agcaagctgg ttctctggga tataaataag catggactgg aggaaacagc
361 tgccaaatgc aagggactgg gtgccaaggt tcataccttt gtggtagact gcagcaaccg
421 agaagatatt tacagctctg caaagaaggt gaaggcagaa attggagatg ttagtatttt
481 agtaaataat gctggtgtag tctatacatc agatttgttt gctacacaag atcctcagat
541 tgaaaagact tttgaagtta atgtacttgc acatttctgg actacaaagg catttcttcc
601 tgcaatgacg aagaataacc atggccatat tgtcactgtg gcttcggcag ctggacatgt
661 ctcggtcccc ttcttactgg cttactgttc aagcaagttt gctgctgttg gatttcataa
721 aactttgaca gatgaactgg ctgccttaca aataactgga gtcaaaacaa catgtctgtg
781 tcctaatttc gtaaacactg gcttcatcaa aaatccaagt acaagtttgg gacccactct
841 ggaacctgag gaagtggtaa acaggctgat gcatgggatt ctgactgagc agaagatgat
901 ttttattcca tcttctatag cttttttaac aacattggaa aggatccttc ctgagcgttt
961 cctggcagtt ttaaaacgaa aaatcagtgt taagtttgat gcagttattg gatataaaat
1021 gaaagcgcaa taagcaccta gttttctgaa aactgattta ccaggtttag gttgatgtca
1081 tctaatagtg ccagaatttt aatgtttgaa cttctgtttt ttctaattat ccccatttct
1141 tcaatatcat ttttgaggct ttggcagtct tcatttacta ccacttgttc tttagccaaa
1201 agctgattac atatgatata aacagagaaa tacctttaga ggtgacttta aggaaaatga
1261 agaaaaagaa ccaaaatgac tttattaaaa taatttccaa gattatttgt ggctcacctg
1321 aaggctttgc aaaatttgta ccataaccgt ttatttaaca tatattttta tttttgattg
1381 cacttaaatt ttgtataatt tgtgtttctt tttctgttct acataaaatc agaaacttca
1441 agctctctaa ataaaatgaa ggactcaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
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