LOCUS BC016140 1930 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens mevalonate kinase, mRNA (cDNA clone MGC:9001
IMAGE:3921543), complete cds.
ACCESSION BC016140
VERSION BC016140.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1930)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1930)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 15 Row: n Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557768.
FEATURES Location/Qualifiers
source 1..1930
/db_xref="H-InvDB:HIT000037477"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9001 IMAGE:3921543"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1930
/gene="MVK"
/gene_synonym="LRBP"
/gene_synonym="MK"
/gene_synonym="MVLK"
/db_xref="GeneID:4598"
/db_xref="HGNC:HGNC:7530"
/db_xref="MIM:251170"
CDS 37..1227
/gene="MVK"
/gene_synonym="LRBP"
/gene_synonym="MK"
/gene_synonym="MVLK"
/codon_start=1
/product="MVK protein"
/protein_id="AAH16140.1"
/db_xref="GeneID:4598"
/db_xref="HGNC:HGNC:7530"
/db_xref="MIM:251170"
/translation="MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPH
SNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCA
VTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTV
CEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQ
GKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECE
RVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGA
GGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQA
LDGL"
BASE COUNT 383 a 589 c 576 g 382 t
ORIGIN
1 gcggcggccg gggaggcggc ggcggcggca ggagccatgt tgtcagaagt cctactggtg
61 tctgctccgg ggaaagtcat ccttcatgga gaacatgccg tggtacatgg caaggtagca
121 ctggctgtat ccttgaactt gagaacattc ctccggcttc aaccccacag caatgggaaa
181 gtggacctca gcttacccaa cattggtatc aagcgggcct gggatgtggc caggcttcag
241 tcactggaca caagctttct ggagcaaggt gatgtcacaa cacccacctc agagcaagtg
301 gagaagctaa aggaggttgc aggcttgcct gacgactgtg ctgtcaccga gcgcctggct
361 gtgctggcct ttctttactt atacctgtcc atctgccgga agcagagggc cctgccgagc
421 ctggatatcg tagtgtggtc ggagctgccc cccggggcgg gcttgggctc cagcgccgcc
481 tactcggtgt gtctggcagc agccctcctg actgtgtgcg aggagatccc aaacccgctg
541 aaggacgggg attgcgtcaa caggtggacc aaggaggatt tggagctaat taacaagtgg
601 gccttccaag gggagagaat gattcacggg aacccctccg gagtggacaa tgctgtcagc
661 acctggggag gagccctccg ataccatcaa gggaagattt catccttaaa gaggtcgcca
721 gctctccaga tcctgctgac caacaccaaa gtccctcgca ataccagggc ccttgtggct
781 ggcgtcagaa acaggctgct caagttccca gagatcgtgg cccccctcct gacctcaata
841 gatgccatct ccctggagtg tgagcgcgtg ctgggagaga tgggggaagc cccagccccg
901 gagcagtacc tcgtgctgga agagctcatt gacatgaacc agcaccatct gaatgccctc
961 ggcgtgggcc acgcctctct ggaccagctc tgccaggtga ccagggcccg cggacttcac
1021 agcaagctga ctggcgcagg cggtggtggc tgtggcatca cactcctcaa gccagggctg
1081 gagcagccag aagtggaggc cacgaagcag gccctgacca gctgtggctt tgactgcttg
1141 gaaaccagca tcggtgcccc cggcgtctcc atccactcag ccacctccct ggacagccga
1201 gtccagcaag ccctggatgg cctctgagag gagcccacga cactgcagcc ccacccagat
1261 gcccctttct ggattattct gggggctgca gttcgactct gtgctggcca gcgagcgccc
1321 agctcctgac actgctggag aggccccagc cgcttggcga tgccagccaa gctctgcagt
1381 cccagcggtg ggacctaggg aggcatggtc tgccctctgc atcctctgga gccagccgag
1441 caggaggcct aggagggtcc tctgagactc cagacctgag gcgagaaggg ctgcttccct
1501 gaagctccca cagtcccatc tgcttcaggc ccccgccttg gcctgtgttc ttcctggccg
1561 cctgggtcca atgctcaggt gctggggcct ggttcccgga gaagtgtgcc ttctctctcc
1621 cttttcaggg accgccccct gtctctcagg gccaggcctc tccctcctcc aggaagcctt
1681 cccctacccc ttgtcgcccc tccctcccag agcacctgct gtctgggtgg ctcactcagc
1741 acttggtgtg gccttccctt ctacctagcg ggatggggct cccccagggg ctgtcccgga
1801 ggcggtgggc ctggttaaat aaggcagggt ttatatgcac tttcttccga tctgtacctg
1861 agaggtttgt ggaaaagatg gcaaatgggg aataaaaaga ttttgtgtca acagtaaaaa
1921 aaaaaaaaaa
//